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Protein-ligand scoring is an important step in a structure-based drug design pipeline. Selecting a correct binding pose and predicting the binding affinity of a protein-ligand complex enables effective virtual screening. Machine learning…

Machine Learning · Statistics 2020-10-19 Joshua Hochuli , Alec Helbling , Tamar Skaist , Matthew Ragoza , David Ryan Koes

Convolutional Neural Networks (CNNs) currently achieve state-of-the-art accuracy in image classification. With a growing number of classes, the accuracy usually drops as the possibilities of confusion increase. Interestingly, the class…

Computer Vision and Pattern Recognition · Computer Science 2017-10-25 Bilal Alsallakh , Amin Jourabloo , Mao Ye , Xiaoming Liu , Liu Ren

Understanding the per-layer learning dynamics of deep neural networks is of significant interest as it may provide insights into how neural networks learn and the potential for better training regimens. We investigate learning in Deep…

Machine Learning · Computer Science 2020-12-02 Ayush Manish Agrawal , Atharva Tendle , Harshvardhan Sikka , Sahib Singh , Amr Kayid

Semantic segmentation and instance level segmentation made substantial progress in recent years due to the emergence of deep neural networks (DNNs). A number of deep architectures with Convolution Neural Networks (CNNs) were proposed that…

Computer Vision and Pattern Recognition · Computer Science 2019-09-18 Pulak Purkait , Christopher Zach , Ian Reid

An important goal in visual recognition is to devise image representations that are invariant to particular transformations. In this paper, we address this goal with a new type of convolutional neural network (CNN) whose invariance is…

Computer Vision and Pattern Recognition · Computer Science 2015-01-08 Julien Mairal , Piotr Koniusz , Zaid Harchaoui , Cordelia Schmid

Finding semantic correspondences is a challenging problem. With the breakthrough of CNNs stronger features are available for tasks like classification but not specifically for the requirements of semantic matching. In the following we…

Computer Vision and Pattern Recognition · Computer Science 2019-06-18 Nikolai Ufer , Kam To Lui , Katja Schwarz , Paul Warkentin , Björn Ommer

In recent years, supervised learning with convolutional networks (CNNs) has seen huge adoption in computer vision applications. Comparatively, unsupervised learning with CNNs has received less attention. In this work we hope to help bridge…

Machine Learning · Computer Science 2016-01-11 Alec Radford , Luke Metz , Soumith Chintala

Understanding how deep convolutional neural networks classify data has been subject to extensive research. This paper proposes a technique to visualize and interpret intermediate layers of unsupervised deep convolutional networks by…

Sound · Computer Science 2022-04-29 Gašper Beguš , Alan Zhou

The convolutional neural networks (CNNs) have proven to be a powerful tool for discriminative learning. Recently researchers have also started to show interest in the generative aspects of CNNs in order to gain a deeper understanding of…

Computer Vision and Pattern Recognition · Computer Science 2015-04-10 Jifeng Dai , Yang Lu , Ying-Nian Wu

Deep learning based on deep neural networks has been very successful in many practical applications, but it lacks enough theoretical understanding due to the network architectures and structures. In this paper we establish some analysis for…

Machine Learning · Computer Science 2024-01-03 Jianfei Li , Han Feng , Ding-Xuan Zhou

Convolutional Neural Networks have become state of the art methods for image classification over the last couple of years. By now they perform better than human subjects on many of the image classification datasets. Most of these datasets…

Computer Vision and Pattern Recognition · Computer Science 2017-08-28 Sebastian Stabinger , Antonio Rodriguez-Sanchez

A major prerequisite for the application of machine learning models in clinical decision making is trust and interpretability. Current explainability studies in the neuroimaging community have mostly focused on explaining individual…

Computer Vision and Pattern Recognition · Computer Science 2022-03-25 Fabian Eitel , Anna Melkonyan , Kerstin Ritter

This work introduces the Topological CNN (TCNN), which encompasses several topologically defined convolutional methods. Manifolds with important relationships to the natural image space are used to parameterize image filters which are used…

Machine Learning · Computer Science 2021-03-05 Ephy R. Love , Benjamin Filippenko , Vasileios Maroulas , Gunnar Carlsson

This paper presents a new state-of-the-art for document image classification and retrieval, using features learned by deep convolutional neural networks (CNNs). In object and scene analysis, deep neural nets are capable of learning a…

Computer Vision and Pattern Recognition · Computer Science 2015-02-26 Adam W. Harley , Alex Ufkes , Konstantinos G. Derpanis

Current research in Computer Vision has shown that Convolutional Neural Networks (CNN) give state-of-the-art performance in many classification tasks and Computer Vision problems. The embedding of CNN, which is the internal representation…

Computer Vision and Pattern Recognition · Computer Science 2015-08-04 Axel Angel

Over the past decade, deep learning has proven to be a highly effective tool for learning meaningful features from raw data. However, it remains an open question how deep networks perform hierarchical feature learning across layers. In this…

Machine Learning · Computer Science 2025-11-17 Peng Wang , Xiao Li , Can Yaras , Zhihui Zhu , Laura Balzano , Wei Hu , Qing Qu

Safety-critical applications require transparency in artificial intelligence (AI) components, but widely used convolutional neural networks (CNNs) widely used for perception tasks lack inherent interpretability. Hence, insights into what…

Computer Vision and Pattern Recognition · Computer Science 2023-06-28 Georgii Mikriukov , Gesina Schwalbe , Christian Hellert , Korinna Bade

Convolutional Neural Networks (CNNs) have achieved comparable error rates to well-trained human on ILSVRC2014 image classification task. To achieve better performance, the complexity of CNNs is continually increasing with deeper and bigger…

Computer Vision and Pattern Recognition · Computer Science 2014-12-30 Wei Yu , Kuiyuan Yang , Yalong Bai , Hongxun Yao , Yong Rui

Deep neural networks (DNNs) are increasingly deployed in different applications to achieve state-of-the-art performance. However, they are often applied as a black box with limited understanding of what knowledge the model has learned from…

Computer Vision and Pattern Recognition · Computer Science 2021-02-09 Shihao Zhao , Xingjun Ma , Yisen Wang , James Bailey , Bo Li , Yu-Gang Jiang

Deep learning has gained great success in various classification tasks. Typically, deep learning models learn underlying features directly from data, and no underlying relationship between classes are included. Similarity between classes…

Computer Vision and Pattern Recognition · Computer Science 2020-09-28 Xueli Xiao , Chunyan Ji , Thosini Bamunu Mudiyanselage , Yi Pan