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In this paper we present a generalized Deep Learning-based approach for solving ill-posed large-scale inverse problems occuring in medical image reconstruction. Recently, Deep Learning methods using iterative neural networks and cascaded…

Image and Video Processing · Electrical Eng. & Systems 2020-08-26 Andreas Kofler , Markus Haltmeier , Tobias Schaeffter , Marc Kachelrieß , Marc Dewey , Christian Wald , Christoph Kolbitsch

Inverse problems are fundamental in fields like medical imaging, geophysics, and computerized tomography, aiming to recover unknown quantities from observed data. However, these problems often lack stability due to noise and…

Numerical Analysis · Mathematics 2024-06-26 Andrea Ebner , Matthias Schwab , Markus Haltmeier

Bayesian inference with computationally expensive likelihood evaluations remains a significant challenge in many scientific domains. We propose normalizing flow regression (NFR), a novel offline inference method for approximating posterior…

Machine Learning · Statistics 2025-04-17 Chengkun Li , Bobby Huggins , Petrus Mikkola , Luigi Acerbi

Ptychography, as an essential tool for high-resolution and nondestructive material characterization, presents a challenging large-scale nonlinear and non-convex inverse problem; however, its intrinsic photon statistics create clear…

Machine Learning · Statistics 2021-11-02 Agnimitra Dasgupta , Zichao Wendy Di

Lack of standardization and various intrinsic parameters for magnetic resonance (MR) image acquisition results in heterogeneous images across different sites and devices, which adversely affects the generalization of deep neural networks.…

Pruning is a model compression method that removes redundant parameters in deep neural networks (DNNs) while maintaining accuracy. Most available filter pruning methods require complex treatments such as iterative pruning, features…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Yue Wu , Yuan Lan , Luchan Zhang , Yang Xiang

The Normalizing Flow (NF) models a general probability density by estimating an invertible transformation applied on samples drawn from a known distribution. We introduce a new type of NF, called Deep Diffeomorphic Normalizing Flow (DDNF).…

Machine Learning · Statistics 2018-11-26 Hadi Salman , Payman Yadollahpour , Tom Fletcher , Kayhan Batmanghelich

The importance of regularization has been well established in image reconstruction -- which is the computational inversion of imaging forward model -- with applications including deconvolution for microscopy, tomographic reconstruction,…

Image and Video Processing · Electrical Eng. & Systems 2021-06-29 Sanjay Viswanath , Manu Ghulyani , Muthuvel Arigovindan

Photoacoustic tomography is a hybrid imaging technique that combines high optical tissue contrast with high ultrasound resolution. Direct reconstruction methods such as filtered backprojection, time reversal and least squares suffer from…

Learning neural networks using only few available information is an important ongoing research topic with tremendous potential for applications. In this paper, we introduce a powerful regularizer for the variational modeling of inverse…

Machine Learning · Computer Science 2023-05-17 Fabian Altekrüger , Alexander Denker , Paul Hagemann , Johannes Hertrich , Peter Maass , Gabriele Steidl

Real-world data with underlying structure, such as pictures of faces, are hypothesized to lie on a low-dimensional manifold. This manifold hypothesis has motivated state-of-the-art generative algorithms that learn low-dimensional data…

Machine Learning · Statistics 2022-04-28 Edmond Cunningham , Renos Zabounidis , Abhinav Agrawal , Madalina Fiterau , Daniel Sheldon

We report a new approach to flow field tomography that uses the Navier-Stokes and advection-diffusion equations to regularize reconstructions. Tomography is increasingly employed to infer 2D or 3D fluid flow and combustion structures from a…

Fluid Dynamics · Physics 2026-03-31 Joseph P. Molnar , Samuel J. Grauer

Many application domains, spanning from computational photography to medical imaging, require recovery of high-fidelity images from noisy, incomplete or partial/compressed measurements. State of the art methods for solving these inverse…

Image and Video Processing · Electrical Eng. & Systems 2022-07-13 Xinyi Wei , Hans van Gorp , Lizeth Gonzalez Carabarin , Daniel Freedman , Yonina C. Eldar , Ruud J. G. van Sloun

Normalizing Flows (NFs) are a classical family of likelihood-based methods that have received revived attention. Recent efforts such as TARFlow have shown that NFs are capable of achieving promising performance on image modeling tasks,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-23 Tianrong Chen , Jiatao Gu , David Berthelot , Joshua Susskind , Shuangfei Zhai

In this work, we describe a new approach that uses deep neural networks (DNN) to obtain regularization parameters for solving inverse problems. We consider a supervised learning approach, where a network is trained to approximate the…

Numerical Analysis · Mathematics 2021-04-15 Babak Maboudi Afkham , Julianne Chung , Matthias Chung

We present a novel approach to transcranial ultrasound computed tomography that utilizes normalizing flows to improve the speed of imaging and provide Bayesian uncertainty quantification. Our method combines physics-informed methods and…

Image and Video Processing · Electrical Eng. & Systems 2023-03-08 Rafael Orozco , Mathias Louboutin , Ali Siahkoohi , Gabrio Rizzuti , Tristan van Leeuwen , Felix Herrmann

In this paper, we investigate image reconstruction for dynamic Computed Tomography. The motion of the target with respect to the measurement acquisition rate leads to highly resolved in time but highly undersampled in space measurements.…

Image and Video Processing · Electrical Eng. & Systems 2025-06-27 Pablo Arratia , Matthias Ehrhardt , Lisa Kreusser

Neural Radiance Fields (NeRF) has emerged as a compelling framework for scene representation and 3D recovery. To improve its performance on real-world data, depth regularizations have proven to be the most effective ones. However, depth…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Aoxiang Fan , Corentin Dumery , Nicolas Talabot , Pascal Fua

Solving inverse problems involving measurement noise and modeling errors requires regularization in order to avoid data overfit. Geophysical inverse problems, in which the Earth's highly heterogeneous structure is unknown, present a…

Geophysics · Physics 2022-03-31 Ali Siahkoohi , Rafael Orozco , Gabrio Rizzuti , Felix J. Herrmann

Diffusion and flow-based generative models have shown strong potential for image restoration. However, image denoising under unknown and varying noise conditions remains challenging, because the learned vector fields may become inconsistent…

Computer Vision and Pattern Recognition · Computer Science 2026-04-06 Jigang Duan , Genwei Ma , Xu Jiang , Wenfeng Xu , Ping Yang , Xing Zhao
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