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Time series analysis is widely used in extensive areas. Recently, to reduce labeling expenses and benefit various tasks, self-supervised pre-training has attracted immense interest. One mainstream paradigm is masked modeling, which…

Machine Learning · Computer Science 2023-10-24 Jiaxiang Dong , Haixu Wu , Haoran Zhang , Li Zhang , Jianmin Wang , Mingsheng Long

Irregular Multivariate Time Series (IMTS) are characterized by uneven intervals between consecutive timestamps, which carry sampling pattern information valuable and informative for learning temporal and variable dependencies. In addition,…

Machine Learning · Computer Science 2026-02-26 Boyuan Li , Zhen Liu , Yicheng Luo , Qianli Ma

Reconstructing precise clinical timelines is essential for modeling patient trajectories and forecasting risk in complex, heterogeneous conditions like sepsis. While unstructured clinical narratives offer semantically rich and contextually…

Computation and Language · Computer Science 2026-05-15 Sayantan Kumar , Shahriar Noroozizadeh , Juyong Kim , Jeremy C. Weiss

Timeseries regression models often struggle to leverage large volumes of labeled multimodal data, particularly when the data are irregularly sampled or contain missing values. This is common in domains like healthcare and predictive…

Machine Learning · Computer Science 2026-05-18 Antoine Honoré , Ming Xiao

Electronic health records (EHRs) recorded in hospital settings typically contain a wide range of numeric time series data that is characterized by high sparsity and irregular observations. Effective modelling for such data must exploit its…

Irregularly sampled time series are increasingly prevalent, particularly in medical domains. While various specialized methods have been developed to handle these irregularities, effectively modeling their complex dynamics and pronounced…

Machine Learning · Computer Science 2023-11-01 Zekun Li , Shiyang Li , Xifeng Yan

Accurate imputation of missing laboratory values in electronic health records (EHRs) is critical to enable robust clinical predictions and reduce biases in AI systems in healthcare. Existing methods, such as XGBoost, softimpute, GAIN,…

Machine Learning · Computer Science 2025-06-27 David Restrepo , Chenwei Wu , Yueran Jia , Jaden K. Sun , Jack Gallifant , Catherine G. Bielick , Yugang Jia , Leo A. Celi

Heterogeneity and irregularity of multi-source data sets present a significant challenge to time-series analysis. In the literature, the fusion of multi-source time-series has been achieved either by using ensemble learning models which…

Machine Learning · Computer Science 2021-10-07 Futoon M. Abushaqra , Hao Xue , Yongli Ren , Flora D. Salim

Deep learning models have proven to be effective on medical datasets for accurate diagnostic predictions from images. However, medical datasets often contain noisy, mislabeled, or poorly generalizable images, particularly for edge cases and…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Ruhaan Singh , Sreelekha Guggilam

This paper studies causal discovery in irregularly sampled time series-a key challenge in risk-sensitive domains like finance, healthcare, and climate science, where missing data and inconsistent sampling frequencies distort causal…

Machine Learning · Computer Science 2026-05-12 Weihong Li , Baohong Li , Anpeng Wu , Zhihan Li , Ming Ma , Keting Yin , Kun Kuang

Irregularly-sampled time series occur in many domains including healthcare. They can be challenging to model because they do not naturally yield a fixed-dimensional representation as required by many standard machine learning models. In…

Machine Learning · Computer Science 2020-08-19 Steven Cheng-Xian Li , Benjamin M. Marlin

Irregularly sampled time series data arise naturally in many application domains including biology, ecology, climate science, astronomy, and health. Such data represent fundamental challenges to many classical models from machine learning…

Machine Learning · Computer Science 2021-01-07 Satya Narayan Shukla , Benjamin M. Marlin

Learning from electronic health records (EHRs) time series is challenging due to irregular sam- pling, heterogeneous missingness, and the resulting sparsity of observations. Prior self-supervised meth- ods either impute before learning,…

Machine Learning · Computer Science 2026-02-18 Xiao Xiang , David Restrepo , Hyewon Jeong , Yugang Jia , Leo Anthony Celi

In several practical applications, particularly healthcare, clinical data of each patient is individually recorded in a database at irregular intervals as required. This causes a sparse and irregularly sampled time series, which makes it…

Machine Learning · Computer Science 2025-04-09 Mincheol Kim , Soo-Yong Shin

Handling anomalies is a critical preprocessing step in multivariate time series prediction. However, existing approaches that separate anomaly preprocessing from model training for multivariate time series prediction encounter significant…

Machine Learning · Computer Science 2025-01-15 Yuanyuan Liang , Tianhao Zhang , Tingyu Xie

Generating realistic time series data is critical for applications in healthcare, finance, and science. However, irregular sampling and missing values present significant challenges. While prior methods address these irregularities, they…

Machine Learning · Computer Science 2025-10-09 Gal Fadlon , Idan Arbiv , Nimrod Berman , Omri Azencot

Inspired by the masked language modeling (MLM) in natural language processing tasks, the masked image modeling (MIM) has been recognized as a strong self-supervised pre-training method in computer vision. However, the high random mask ratio…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Zhaowen Li , Yousong Zhu , Zhiyang Chen , Wei Li , Chaoyang Zhao , Rui Zhao , Ming Tang , Jinqiao Wang

Time series anomaly detection is a critical task across various industrial domains. However, capturing temporal dependencies and multivariate correlations within patch-level representation learning remains underexplored, and reliance on…

Machine Learning · Computer Science 2026-02-04 Jinwoo Park , Hyeongwon Kang , Seung Hun Han , Pilsung Kang

Irregular multivariate time series (IMTS) are prevalent in critical domains like healthcare and finance, where accurate forecasting is vital for proactive decision-making. However, the asynchronous sampling and irregular intervals inherent…

Machine Learning · Computer Science 2026-03-16 Xvyuan Liu , Xiangfei Qiu , Hanyin Cheng , Xingjian Wu , Chenjuan Guo , Bin Yang , Jilin Hu

Irregular sampling and high missingness are intrinsic challenges in modeling time series derived from electronic health records (EHRs),where clinical variables are measured at uneven intervals depending on workflow and intervention timing.…

Machine Learning · Computer Science 2025-09-29 Jeong Eul Kwon , Joo Heung Yoon , Hyo Kyung Lee