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This study performs parameter inference in a partial differential equations system of pulmonary circulation. We use a fluid dynamics network model that takes selected parameter values and mimics the behaviour of the pulmonary haemodynamics…

This brief article accompanies a fluid dynamics video presenting the results of a large-eddy simulation of the flow in a realistic left heart. The left heart geometry, from the pulmonary veins to the aortic root, is extracted from medical…

Fluid Dynamics · Physics 2013-10-14 Christophe Chnafa , Simon Mendez , Franck Nicoud

Accurate simulations of the flow in the human airway are essential for advancing diagnostic methods. Many existing computational studies rely on simplified geometries or turbulence models, limiting their simulation's ability to resolve flow…

Numerical simulations to evaluate thoracic aortic hemodynamics include a computational fluid dynamic (CFD) approach or fluid-structure interaction (FSI) approach. While CFD neglects the arterial deformation along the cardiac cycle by…

Turbulent concentric coaxial (annular) pipe flow is numerically investigated using a stochastic one-dimensional turbulence (ODT) model as a stand-alone tool. The dimensionally reduced ODT domain enables fully resolved numerical simulations…

Fluid Dynamics · Physics 2026-02-04 Pei-Yun Tsai , Marten Klein , Heiko Schmidt

Several cardiovascular diseases are caused from localised abnormal blood flow such as in the case of stenosis or aneurysms. Prevailing theories propose that the development is caused by abnormal wall-shear stress in focused areas.…

Optimization and Control · Mathematics 2016-07-12 S. W. Funke , M. Nordaas , Øyvind Evju , M. S. Alnæs , K. -A. Mardal

In this work, we present a coupled 3D-1D model of solid tumor growth within a dynamically changing vascular network to facilitate realistic simulations of angiogenesis. Additionally, the model includes erosion of the extracellular matrix,…

Tissues and Organs · Quantitative Biology 2021-06-23 Marvin Fritz , Prashant K. Jha , Tobias Köppl , J. Tinsley Oden , Andreas Wagner , Barbara Wohlmuth

We experimentally and numerically investigate the flow of a Newtonian fluid through a constricted geometry for Reynolds numbers in the range $0.1 - 100$. The major aim is to study non-linear inertia effects at larger Reynolds numbers (>10)…

- Modeling Human cardiovascular system is always an important issue. One of the most effective methods is using lumped model to reach to a complete model of human cardiovascular system. Such modeling with advanced considerations is used in…

Blood vessel constriction is simulated with particle-based method using a molecular dynamics authoring software known as Molecular Workbench (WM). Blood flow and vessel wall, the only components considered in constructing a blood vessel,…

Biological Physics · Physics 2014-04-01 Mohamad Rendi , Suprijadi , Sparisoma Viridi

We present a model appropriate to the initial motion (2-3 chords of travel) of a flat-plate airfoil accelerating in an inviscid fluid. The separated flow structures are represented as vortex sheets in the conventional manner and similarity…

Fluid Dynamics · Physics 2021-05-19 A. C. DeVoria , K. Mohseni

The present focus of heart flow studies is largely based on flow within the left ventricle and how this flow changes when subject to disease. However, despite recent advancements, a simple tractable model of even healthy left ventricular…

Fluid Dynamics · Physics 2019-03-18 Giuseppe Di Labbio , Lyes Kadem

We investigate flow pattern formation and viscosity reduction mechanisms in active fluids by studying a generalized Navier-Stokes model that captures the experimentally observed bulk vortex dynamics in microbial suspensions. We present…

Fluid Dynamics · Physics 2017-05-03 Jonasz Słomka , Jörn Dunkel

We present a novel mathematical model that simulates myocardial blood perfusion by embedding multiscale and multiphysics features. Our model incorporates cardiac electrophysiology, active and passive mechanics, hemodynamics, reduced valve…

Computational Engineering, Finance, and Science · Computer Science 2023-03-27 Alberto Zingaro , Christian Vergara , Luca Dede' , Francesco Regazzoni , Alfio Quarteroni

The simulation of blood flow and pressure in arteries requires outflow boundary conditions that incorporate models of downstream domains. We previously described a coupled multidomain method to couple analytical models of the downstream…

Medical Physics · Physics 2020-07-17 Irene Vignon-Clementel , C. A. Figueroa , K. E. Jansen , C. A. Taylor

Hemodynamic parameters such as pressure and wall shear stress play an important role in diagnosis, prognosis, and treatment planning in cardiovascular diseases. These parameters can be accurately computed using computational fluid dynamics…

Computer Vision and Pattern Recognition · Computer Science 2025-08-28 Patryk Rygiel , Julian Suk , Kak Khee Yeung , Christoph Brune , Jelmer M. Wolterink

In our recent work, we introduced the reduced unified continuum formulation for vascular fluid-structure interaction (FSI) and demonstrated enhanced solver accuracy, scalability, and performance compared to conventional approaches. We…

Computational Physics · Physics 2022-03-03 Ingrid S. Lan , Ju Liu , Weiguang Yang , Judith Zimmermann , Daniel B. Ennis , Alison L. Marsden

Hemodynamics in the aorta from computational fluid dynamics (CFD) simulations can provide a comprehensive analysis of relevant cardiovascular diseases. Coupling the three-element Windkessel model with the patient-specific CFD simulation to…

Fluid Dynamics · Physics 2022-07-14 Zongze Li , Wenbin Mao

In this paper, a lower bound estimate on the uniform radius of spatial analyticity is established for solutions to the incompressible, forced Navier-Stokes system on an n-torus. This estimate improves or matches previously known estimates…

Analysis of PDEs · Mathematics 2015-06-17 Animikh Biswas , Michael S. Jolly , Vincent R. Martinez , Edriss S. Titi

Arterial deformations arise in blood flow when surrounding tissue invades the space available for a blood vessel to maintain its circular cross section, the most immediate effects being a reduction in blood flow and redistribution of shear…

Tissues and Organs · Quantitative Biology 2023-04-05 Chris Brimacombe , Robert M. Corless , Mair Zamir