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In this paper, we present a mathematical and numerical model for blood solidification and its rupture in stenosed arteries. The interaction between the blood flow and an existing stenosis in the arterial wall is modeled as a three…

Numerical Analysis · Mathematics 2020-05-15 Fatima Abbas , Ayman Mourad

One-dimensional (1D) blood flow simulations are extensively used in cardiovascular research due to their computational efficiency and effectiveness in analyzing pulse wave dynamics. Despite their versatility and simplicity, there is a lack…

Quantitative Methods · Quantitative Biology 2025-08-27 Daehyun Kim , Jeffrey Tithof

In the last years, medical computer simulation has seen a great growth in several scientific branches, from modelling to numerical methods, going through computer science. The main goals of this incipient discipline are testing hypotheses…

Fluid Dynamics · Physics 2017-10-20 Cristóbal Rodero Gómez

Using analytical expressions for the pressure and velocity waveforms in tapered vessels, we construct a linear 1D model for wave propagation in stenotic vessels in the frequency domain. We demonstrate that using only two parameters to…

Fluid Dynamics · Physics 2019-07-24 George Papadakis , Jean Raspaud

Numerical predictions of blood flow and hemodynamic properties through a stenotic and aneurysmal rigid artery are studied in the presence of blood clot at constricted area. Finite element method has been used to solve the steady partial…

Fluid Dynamics · Physics 2020-05-20 Mohammed Nasir Uddin , M. Monir Uddin , Md. Monjarul Alam

In this work, we present mixed dimensional models for simulating blood flow and transport processes in breast tissue and the vascular tree supplying it. These processes are considered, to start from the aortic inlet to the capillaries and…

Tissues and Organs · Quantitative Biology 2022-10-10 Marvin Fritz , Tobias Köppl , J. Tinsley Oden , Andreas Wagner , Barbara Wohlmuth , Chengyue Wu

Reduced-order models based on physics are a popular choice in cardiovascular modeling due to their efficiency, but they may experience reduced accuracy when working with anatomies that contain numerous junctions or pathological conditions.…

In this work, we consider two kinds of model reduction techniques to simulate blood flow through the largest systemic arteries, where a stenosis is located in a peripheral artery i.e. in an artery that is located far away from the heart.…

Numerical Analysis · Mathematics 2018-10-09 Tobias Köppl , Gabriele Santin , Bernard Haasdonk , Rainer Helmig

In this paper, a multiscale constitutive framework for one-dimensional blood flow modeling is presented and discussed. By analyzing the asymptotic limits of the proposed model, it is shown that different types of blood propagation phenomena…

Numerical Analysis · Mathematics 2023-12-13 Giulia Bertaglia , Lorenzo Pareschi

Establishing patient-specific finite element analysis (FEA) models for computational fluid dynamics (CFD) of double stenosed artery models involves time and effort, restricting physicians' ability to respond quickly in time-critical medical…

Medical Physics · Physics 2022-02-18 Ishat Raihan Jamil , Mayeesha Humaira

We are interested in a reduced order method for the efficient simulation of blood flow in arteries. The blood dynamics is modeled by means of the incompressible Navier-Stokes equations. Our algorithm is based on an approximated…

Numerical Analysis · Mathematics 2021-04-07 Luca Pegolotti , Martin Pfaller , Alison Marsden , Simone Deparis

Blood flow in arterial systems can be described by the three-dimensional Navier-Stokes equations within a time-dependent spatial domain that accounts for the elasticity of the arterial walls. In this article blood is treated as an…

Numerical Analysis · Mathematics 2018-08-14 Francesco Fambri , Michael Dumbser , Vincenzo Casulli

We propose and analyze a hierarchy of three models of blood perfusion through a tissue surrounding a thin arteriole or venule. Our goal is to rigorously link 3D-3D Darcy--Stokes, 3D-1D Darcy--Poiseuille, and 1D Green's function methods…

Analysis of PDEs · Mathematics 2025-07-18 Laurel Ohm , Sarah Strikwerda

To address the issue of computational efficiency related to the modelling of blood flow in complex networks, we derive a family of nonlinear lumped-parameter models for blood flow in compliant vessels departing from a well-established…

Numerical Analysis · Mathematics 2022-01-06 Beatrice Ghitti , Eleuterio F. Toro , Lucas O. Müller

We derive a unidirectional asymptotic model for one-dimensional blood flow in viscoelastic arteries. We prove local well-posedness of strong solutions in Sobolev spaces for general parameters and mean-zero periodic data. In the purely…

Analysis of PDEs · Mathematics 2026-04-08 Diego Alonso-Orán , Rafael Granero-Belinchón , Carlos Yanes Pérez

Coronary heart disease (CHD) remains a leading cause of mortality worldwide. This study introduces a novel approach that integrates patient-specific Multi-slice CT scans into CAD models, using a one-dimensional numerical framework to assess…

Medical Physics · Physics 2025-05-21 Priyanshu Ghosh , Sayan Karmakar , Disha Mondal , Oeshee Roy , Supratim Saha

We introduce an innovative lumped-parameter model of the aortic valve, designed to efficiently simulate the impact of valve dynamics on blood flow. Our reduced model includes the elastic effects associated with the leaflets' curvature and…

Numerical Analysis · Mathematics 2025-04-15 Ivan Fumagalli , Luca Dede' , Alfio Quarteroni

We illustrate the potential of PDE-based traffic flow control in cardiovascular flow analysis, monitoring, and control, presenting a PDE-based control-oriented formulation, for 1-D blood flow dynamics in the presence of stenosis. This is…

Optimization and Control · Mathematics 2021-12-23 Nikolaos Bekiaris-Liberis

This paper presents a theoretical study of blood flow through a tapered and overlapping stenosed artery under the action of an externally applied magnetic field. The fluid (blood) medium is assumed to be porous in nature. The variable…

Numerical Analysis · Mathematics 2012-09-25 G. C. Shit , M. Roy , A. Sinha

A new two-dimensional model for blood flows in arteries with arbitrary cross sections is derived. The model consists of a system of balance laws for conservation of mass and balance of momentum in the axial and angular directions. The…

Numerical Analysis · Mathematics 2021-08-23 Cesar Alberto Rosales-Alcantar , Gerardo Hernandez-Duenas
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