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We present a Fisher-information (FI) framework for photon-efficient fluorescence lifetime imaging microscopy (FLIM) that treats temporal sampling as a controllable design variable under a fixed photon (dose) budget. Starting from a Poisson…

Instrumentation and Detectors · Physics 2026-01-05 J. Sumaya-Martinez , E. Torres-Garcia

The problem of recovering signals of high complexity from low quality sensing devices is analyzed via a combination of tools from signal processing and harmonic analysis. By using the rich structure offered by the recent development in…

Information Theory · Computer Science 2020-03-16 Roza Aceska , Jean-Luc Bouchot , Shidong Li

We present a novel and simple method to numerically calculate Fisher Information Matrices for stochastic chemical kinetics models. The linear noise approximation is used to derive model equations and a likelihood function which leads to an…

Applications · Statistics 2015-05-27 Michal Komorowski , Maria J. Costa , David A. Rand , Michael Stumpf

Due to the tremendous cost of seismic data acquisition, methods have been developed to reduce the amount of data acquired by designing optimal missing trace reconstruction algorithms. These technologies are designed to record as little data…

Spectral Theory · Mathematics 2024-01-01 Yijun Zhang , Mathias Louboutin , Ali Siahkoohi , Ziyi Yin , Rajiv Kumar , Felix J. Herrmann

Compressed sensing is triggering a major evolution in signal acquisition. It consists in sampling a sparse signal at low rate and later using computational power for its exact reconstruction, so that only the necessary information is…

Statistical Mechanics · Physics 2012-06-07 Florent Krzakala , Marc Mézard , François Sausset , Yifan Sun , Lenka Zdeborová

The efficacy of mathematical models heavily depends on the quality of the training data, yet collecting sufficient data is often expensive and challenging. Many modeling applications require inferring parameters only as a means to predict…

In ultrasound nondestructive testing, a widespread approach is to take synthetic aperture measurements from the surface of a specimen to detect and locate defects within it. Based on these measurements, imaging is usually performed using…

Signal Processing · Electrical Eng. & Systems 2020-12-09 Jan Kirchhof , Sebastian Semper , Christoph W. Wagner , Eduardo Pérez , Florian Römer , Giovanni Del Galdo

A spatially distributed system contains a large amount of agents with limited sensing, data processing, and communication capabilities. Recent technological advances have opened up possibilities to deploy spatially distributed systems for…

Information Theory · Computer Science 2015-11-30 Cheng Cheng , Yingchun Jiang , Qiyu Sun

Even though image signals are typically defined on a regular two-dimensional grid, there also exist many scenarios where this is not the case and the amplitude of the image signal only is available for a non-regular subset of pixel…

Image and Video Processing · Electrical Eng. & Systems 2022-04-28 Jürgen Seiler , Markus Jonscher , Michael Schöberl , André Kaup

Optimal sensor placement is a central challenge in the design, prediction, estimation, and control of high-dimensional systems. High-dimensional states can often leverage a latent low-dimensional representation, and this inherent…

Optimization and Control · Mathematics 2020-05-18 Krithika Manohar , Bingni W. Brunton , J. Nathan Kutz , Steven L. Brunton

Computational capability often falls short when confronted with massive data, posing a common challenge in establishing a statistical model or statistical inference method dealing with big data. While subsampling techniques have been…

Methodology · Statistics 2024-10-31 Yixiao Ruan , Zan Li , Zhaohui Li , Dennis K. J. Lin , Qingpei Hu , Dan Yu

We study the compressed sensing reconstruction problem for a broad class of random, band-diagonal sensing matrices. This construction is inspired by the idea of spatial coupling in coding theory. As demonstrated heuristically and…

Information Theory · Computer Science 2015-03-19 David L. Donoho , Adel Javanmard , Andrea Montanari

Reconstruction of structure and parameters of an Ising model from binary samples is a problem of practical importance in a variety of disciplines, ranging from statistical physics and computational biology to image processing and machine…

Statistical Mechanics · Physics 2017-12-27 Andrey Y. Lokhov , Marc Vuffray , Sidhant Misra , Michael Chertkov

Networked sensing, where the goal is to perform complex inference using a large number of inexpensive and decentralized sensors, has become an increasingly attractive research topic due to its applications in wireless sensor networks and…

Machine Learning · Statistics 2017-01-04 Yuejie Chi , Haoyu Fu

Matrix recovery from sparse observations is an extensively studied topic emerging in various applications, such as recommendation system and signal processing, which includes the matrix completion and compressed sensing models as special…

Methodology · Statistics 2026-04-13 Ziyuan Chen , Ying Yang , Fang Yao

We present a statistical framework to benchmark the performance of reconstruction algorithms for linear inverse problems, in particular, neural-network-based methods that require large quantities of training data. We generate synthetic…

Signal Processing · Electrical Eng. & Systems 2023-07-05 Pakshal Bohra , Pol del Aguila Pla , Jean-François Giovannelli , Michael Unser

Fine-tuning all the layers of a pre-trained neural language encoder (either using all the parameters or using parameter-efficient methods) is often the de-facto way of adapting it to a new task. We show evidence that for different…

Compressive sensing is a technique to sample signals well below the Nyquist rate using linear measurement operators. In this paper we present an algorithm for signal reconstruction given such a set of measurements. This algorithm…

Information Theory · Computer Science 2009-06-08 Graeme Pope

Graphical models are useful tools for describing structured high-dimensional probability distributions. Development of efficient algorithms for learning graphical models with least amount of data remains an active research topic.…

Machine Learning · Computer Science 2021-11-18 Marc Vuffray , Sidhant Misra , Andrey Y. Lokhov

In this paper we study the performance of image reconstruction methods from incomplete samples of the 2D discrete Fourier transform. Inspired by requirements in parallel MRI, we focus on a special sampling pattern with a small number of…

Numerical Analysis · Mathematics 2025-10-22 Gerlind Plonka , Anahita Riahi