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Related papers: Dual-Comb Photothermal Microscopy

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Owing to its capacity for unique (bio)-chemical specificity, microscopy withmid-IR illumination holds tremendous promise for a wide range of biomedical and industrial applications. The primary limitation, however, remains detection; with…

Mid-infrared semiconductor lasers in photonic integrated circuits are of considerable interest for a variety of industrial, environmental, and medical applications. However, photonic integration technologies in the mid-infrared lag far…

Light detection and ranging (LIDAR) is critical to many fields in science and industry. Over the last decade, optical frequency combs were shown to offer unique advantages in optical ranging, in particular when it comes to fast distance…

Broadband and high-resolution spectroscopy in the visible and ultraviolet is central to advances in multiple fields, including fundamental quantum physics, biology, atmospheric science and astronomy. Traditionally, these measurements are…

The detection of light of thermal origin is the principal means by which humanity has learned about our world and the cosmos. In optical astronomy, in particular, direct detection of thermal photons and the resolution of their spectra have…

Laser dynamics underpin a broad range of modern photonic technologies and continue to reveal rich nonlinear behaviors. However, existing spectroscopic tools, most notably time-stretched dispersive Fourier transform spectroscopy (TS-DFT),…

Mid-wave infrared (MWIR) frequency comb is expected to dramatically improve the precision and sensitivity of molecular spectroscopy. For high resolution application, high speed MWIR photodetector is one of the key components, however, the…

Applied Physics · Physics 2023-07-19 Jian Huang , Zhiyang Xie , Yaojiang Chen , John Bowers , Baile Chen

Mid-infrared photothermal (MIP) microscopy has been a promising label-free chemical imaging technique for functional characterization of specimens owing to its enhanced spatial resolution and high specificity. Recently developed wide-field…

Optical spectroscopy and imaging of microscopic samples have opened up a wide range of applications throughout the physical, chemical, and biological sciences. High chemical specificity may be achieved by directly interrogating the…

Coherent anti-Stokes Raman scattering (CARS) spectroscopy with time-delayed ultrashort pulses and a single-pixel photodetector has shown great potential for spectroscopic imaging and transient studies in chemistry and biological research.…

Optics · Physics 2023-12-05 Tianjian Lv , Bing Han , Ming Yan , Zhaoyang Wen , Kun Huang , Kangwen Yang , Heping Zeng

Fourier-transform spectroscopy is an indispensable tool for analyzing chemical samples in scientific research as well as chemical and pharmaceutical industries. Recently, its measurement speed, sensitivity, and precision have been shown to…

Optics · Physics 2025-05-06 Takuro Ideguchi , Tasuku Nakamura , Yohei Kobayashi , Keisuke Goda

Molecular diagnostics are a primary tool of modern chemistry, enabling researchers to map chemical reaction pathways and rates to better design and control chemical systems. Many chemical reactions are complex and fast, and existing…

Dual-comb ranging has emerged as an effective technology for long-distance metrology, providing absolute distance measurements with high speed, precision, and accuracy. Here, we demonstrate a dual-comb ranging method that utilizes a…

We demonstrate 1D simultaneous laser cooling of $^{87}$Rb and $^{85}$Rb atoms using an optical frequency comb. By adjusting the pulse repetition frequency and the offset frequency, the frequency comb spectrum is tuned to ensure that two…

Atomic Physics · Physics 2020-09-02 D. Buhin , D. Kovacic , F. Schmid , M. Kruljac , V. Vulic , T. Ban , D. Aumiler

We report a high-energy, bidirectional, dissipative soliton mode-locked fiber laser operating in the 1550 nm normal-dispersion regime. By leveraging intracavity dispersion management and a Lyot filtering mechanism, the laser achieves…

Optics · Physics 2026-02-17 Mingjun Wang , Zhangru Shi , Anshuang Wang , Bowen Li

Photothermal microscopy is an emerging tool for measuring light-matter interactions with single-molecule sensitivity. It is generally believed that the spectral acquisition speed in photothermal microscopy is limited by the slow thermal…

The mid-infrared spectral range (2 to 20 \mu m) is of particular importance for chemistry, biology and physics as many molecules exhibit strong ro-vibrational fingerprints. Frequency combs - broad spectral bandwidth coherent light sources…

Molecular spectroscopy in the mid-infrared portion of the electromagnetic spectrum (3--25 um) has been a cornerstone interdisciplinary analytical technique widely adapted across the biological, chemical, and physical sciences. Applications…

Instrumentation and Detectors · Physics 2018-09-18 Abijith S. Kowligy , Henry Timmers , Alex Lind , Ugaitz Elu , Flavio C. Cruz , Peter G. Schunemann , Jens Biegert , Scott A. Diddams

Mid-infrared hyperspectral imaging has become an indispensable tool to spatially resolve chemical information in a wide variety of samples. However, acquiring three-dimensional data cubes is typically time-consuming due to the limited speed…

Optics · Physics 2026-05-29 Jianan Fang , Kun Huang , Ruiyang Qin , Yan Liang , E Wu , Ming Yan , Heping Zeng

Advancement in mid-infrared (MIR) technology has led to promising biomedical applications of MIR spectroscopy, such as liquid biopsy or breath diagnosis. On the contrary, MIR microscopy has been rarely used for live biological samples in an…