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Biomolecular condensates help organize the cell cytoplasm and nucleoplasm into spatial compartments with different chemical compositions. A key feature of such compositional patterning is the local enrichment of enzymatically active…

Biological Physics · Physics 2024-08-06 Andriy Goychuk , Leonardo Demarchi , Ivan Maryshev , Erwin Frey

Living and engineered systems rely on the stable coexistence of two interspersed liquid phases. Yet surface tension drives their complete separation. Here we show that stable droplets of uniform and tuneable size can be produced through…

Biomolecular condensates formed through the phase separation of proteins and nucleic acids are widely observed, offering a fundamental means of organizing intracellular materials in a membrane-less fashion. Traditionally, these condensates…

Soft Condensed Matter · Physics 2023-10-10 Guang Shi , Kenneth S. Schweizer

The size dependence of the equilibrium droplet contact angle is governed by line tension. In this work, we identify a contribution to line tension arising from gravitational effects and pressure-induced changes in volume-fraction-dependent…

Fluid Dynamics · Physics 2026-02-23 Franziska Aurbach , Fei Wang , Britta Nestler

The formation of (bio)molecular condensates via liquid-liquid phase separation in cells has received increasing attention, as these coacervates play important functional and regulatory roles within biological systems. However, the majority…

Soft Condensed Matter · Physics 2022-11-24 Arash Nikoubashman , Miho Yanagisawa

We present molecular dynamics simulations on the slow dynamics of a mixture of big and small soft-spheres with a large size disparity. Dynamics are investigated in a broad range of temperature and mixture composition. As a consequence of…

Soft Condensed Matter · Physics 2009-11-11 Angel J. Moreno , Juan Colmenero

Demixing of multicomponent biomolecular systems via liquid-liquid phase separation (LLPS) has emerged as a potentially unifying mechanism governing the formation of several membrane-less intracellular organelles ("condensates"), both in the…

Soft Condensed Matter · Physics 2022-10-04 Pierre Ronceray , Sheng Mao , Andrej Košmrlj , Mikko P. Haataja

Collisional growth of tiny particles is a fundamental process governing the growth of cloud droplets and the aggregation of ash particles in volcanic plumes, with direct implications for precipitation formation, cloud lifetime, and ash…

Fluid Dynamics · Physics 2026-01-01 Srikumar Warrier , Anubhab Roy , Pijush Patra

Motivated by the buckling of glassy crusts formed on evaporating droplets of polymer and colloid solutions, we numerically model the deformation and buckling of spherical elastic caps controlled by varying the volume between the shell and…

Materials Science · Physics 2009-11-11 D. A. Head

We investigate the collective dynamics of self-propelled droplets, confined in a one dimensional micro-fluidic channel. On one hand, neighboring droplets align and form large trains of droplets moving in the same direction. On the other…

Soft Condensed Matter · Physics 2020-05-14 Pierre Illien , Charlotte de Blois , Yang Liu , Marjolein N. van der Linden , Olivier Dauchot

The jumping-droplet condensation, namely the out-of-plane jumping of condensed droplets upon coalescence, has been a promising technical innovation in the fields of energy harvesting, droplet manipulation, thermal management, etc., yet is…

Fluid Dynamics · Physics 2024-08-26 Shan Gao , Jian Qu , Zhichun Liu , Weigang Ma

The study of interactions between biomimetic membranes and micron-sized particles is crucial for understanding various biological processes. Here, we control microparticle spontaneous engulfment by giant lipid vesicles by tuning particle…

Soft Condensed Matter · Physics 2025-01-22 Clément Marque , Gaetano D'Avino , Domenico Larobina , Aude Michel , Ali Abou-Hassan , Antonio Stocco

Cells regulate gene expression in part by forming DNA-protein condensates in the nucleus. While existing theories describe the equilibrium size and stability of such condensates, their dynamics remain less understood. Here, we use…

Soft Condensed Matter · Physics 2025-12-22 Adam R. Lamson , Mohammadhossein Firouznia , Michael J. Shelley

As is well known in electrolyte theory, electrostatic fields are attenuated by the presence of mobile charges in the solution. This seems to limit the possibility of an electrostatic repulsion model of biological interactions such as cell…

Biological Physics · Physics 2012-01-04 Eshel Faraggi

Liquid mixtures of many interacting components often exhibit numerous coexisting types of droplets. An exciting example is the cytosol of biological cells, where diverse droplets, called condensates, are essential for cellular function.…

Soft Condensed Matter · Physics 2025-05-28 Yicheng Qiang , Chengjie Luo , David Zwicker

We study the elasto-plastic behavior of dense attractive emulsions under mechanical perturbation. The attraction is introduced through non-specific depletion interactions between the droplets and is controlled by changing the concentration…

The stability of shapes formed by three viscoelastic droplets during their arrested coalescence has been investigated using micromanipulation experiments. Addition of a third droplet to arrested droplet doublets is shown to be controlled by…

The present work investigates the internal flow structure of two condensing droplets of aqueous solution during interaction. The velocity of fluid inside the droplets was investigated by confocal micro-PIV technique. Condensation on the…

Fluid Dynamics · Physics 2020-07-27 Tapan Kumar Pradhan , Pradipta Kumar Panigrahi

We study the effect of inter-condensate dipole-dipole interactions in a setup consisting of physically disconnected, single-species dipolar Bose-Einstein condensates. In particular, making use of the long-range and anisotropic nature of…

Quantum Gases · Physics 2024-11-28 Pranay Nayak , Ratheejit Ghosh , Rejish Nath

Gas hydrates are crystalline compounds formed when water molecules encapsulate guest gas molecules under high pressure and low temperatures. They have gained significant interest due to their potential as alternative energy resources and…

Chemical Physics · Physics 2025-11-14 Ramkhelavan Kanaujiya , Atanu K. Metya , Rajnish Kumar , Tarak K Patra