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Automated medical coding is a process of codifying clinical notes to appropriate diagnosis and procedure codes automatically from the standard taxonomies such as ICD (International Classification of Diseases) and CPT (Current Procedure…

Machine Learning · Computer Science 2022-07-15 Jeshuren Chelladurai , Sudarsun Santhiappan , Balaraman Ravindran

The advancement of natural language processing (NLP) has been significantly boosted by the development of transformer-based large language models (LLMs). These models have revolutionized NLP tasks, particularly in code generation, aiding…

Computation and Language · Computer Science 2024-05-27 Dong Huang , Jie M. Zhang , Michael Luck , Qingwen Bu , Yuhao Qing , Heming Cui

International Classification of Disease (ICD) coding procedure which refers to tagging medical notes with diagnosis codes has been shown to be effective and crucial to the billing system in medical sector. Currently, ICD codes are assigned…

Computation and Language · Computer Science 2021-04-22 Biplob Biswas , Thai-Hoang Pham , Ping Zhang

ICD Coding aims to assign a wide range of medical codes to a medical text document, which is a popular and challenging task in the healthcare domain. To alleviate the problems of long-tail distribution and the lack of annotations of…

Computation and Language · Computer Science 2025-05-27 Xu Zhang , Kun Zhang , Wenxin Ma , Rongsheng Wang , Chenxu Wu , Yingtai Li , S. Kevin Zhou

As software security threats continue to evolve, the demand for innovative ways of securing coding has tremendously grown. The integration of Generative AI (GenAI) into software development holds significant potential for improving secure…

Software Engineering · Computer Science 2025-04-29 Hathal S. Alwageed , Rafiq Ahmad Khan

In medical coding, experts map unstructured clinical notes to alphanumeric codes for diagnoses and procedures. We introduce Code Like Humans: a new agentic framework for medical coding with large language models. It implements official…

Artificial Intelligence · Computer Science 2025-10-09 Andreas Motzfeldt , Joakim Edin , Casper L. Christensen , Christian Hardmeier , Lars Maaløe , Anna Rogers

Medical coding, the translation of unstructured clinical text into standardized medical codes, is a crucial but time-consuming healthcare practice. Though large language models (LLM) could automate the coding process and improve the…

Computation and Language · Computer Science 2025-03-25 John Wu , David Wu , Jimeng Sun

Embedding models have become essential for retrieval-augmented generation (RAG) tasks, semantic clustering, and text re-ranking. But despite their growing use, many of these come with notable limitations. For example, Jina fails to capture…

Information Retrieval · Computer Science 2025-05-21 Anand Selvadurai , Jasheen Shaik , Girish Chandrasekar , ShriRadhaKrishnan Balamurugan , Eswara Reddy

AI is transforming pharmaceutical search, where traditional systems struggle with multimodal content and manual curation. Finder is a scalable AI-powered framework that unifies retrieval across text, images, audio, and video using hybrid…

Information Retrieval · Computer Science 2026-03-18 Suyash Mishra , Srikanth Patil , Satyanarayan Pati , Sagar Sahu , Baddu Narendra

Medical code assignment from clinical text is a fundamental task in clinical information system management. As medical notes are typically lengthy and the medical coding system's code space is large, this task is a long-standing challenge.…

Computation and Language · Computer Science 2022-03-16 Shaoxiong Ji , Shirui Pan , Pekka Marttinen

Generative AI has the potential to transform knowledge work, but further research is needed to understand how knowledge workers envision using and interacting with generative AI. We investigate the development of generative AI tools to…

Background: As of 2026, Large Language Models (LLMs) demonstrate expert-level medical knowledge. However, deploying them as autonomous "Clinical Agents" remains limited. Current Electronic Medical Records (EMRs) and standards like FHIR are…

Artificial Intelligence · Computer Science 2026-05-26 Takahito Nakajima

Artificial intelligence (AI)-driven methods can vastly improve the historically costly drug design process, with various generative models already in widespread use. Generative models for de novo drug design, in particular, focus on the…

Biomolecules · Quantitative Biology 2024-06-27 Xiangru Tang , Howard Dai , Elizabeth Knight , Fang Wu , Yunyang Li , Tianxiao Li , Mark Gerstein

This paper presents a comprehensive systematic review of generative models (GANs, VAEs, DMs, and LLMs) used to synthesize various medical data types, including imaging (dermoscopic, mammographic, ultrasound, CT, MRI, and X-ray), text,…

Although the International Classification of Diseases (ICD) has been adopted worldwide, manually assigning ICD codes to clinical text is time-consuming, error-prone, and expensive, motivating the development of automated approaches. This…

Computation and Language · Computer Science 2024-02-06 Gonçalo Gomes , Isabel Coutinho , Bruno Martins

Recent advancements in natural language processing (NLP) have led to automation in various domains. However, clinical NLP often relies on benchmark datasets that may not reflect real-world scenarios accurately. Automatic ICD coding, a vital…

Computation and Language · Computer Science 2024-07-25 Abhijith R. Beeravolu , Mirjam Jonkman , Sami Azam , Friso De Boer

The task of assigning diagnostic ICD codes to patient hospital admissions is typically performed by expert human coders. Efforts towards automated ICD coding are dominated by supervised deep learning models. However, difficulties in…

Artificial Intelligence · Computer Science 2023-11-14 Joseph S. Boyle , Antanas Kascenas , Pat Lok , Maria Liakata , Alison Q. O'Neil

Automatically generating source code from natural language descriptions has been a growing field of research in recent years. However, current large-scale code generation models often encounter difficulties when selecting appropriate APIs…

Software Engineering · Computer Science 2023-09-12 Kechi Zhang , Huangzhao Zhang , Ge Li , Jia Li , Zhuo Li , Zhi Jin

Automatic medical coding has the potential to ease documentation and billing processes. For this task, transparency plays an important role for medical coders and regulatory bodies, which can be achieved using explainability methods.…

Computation and Language · Computer Science 2025-07-03 Katharina Beckh , Elisa Studeny , Sujan Sai Gannamaneni , Dario Antweiler , Stefan Rüping

The rapid development of generative AI has transformed content creation, communication, and human development. However, this technology raises profound concerns in high-stakes domains, demanding rigorous methods to analyze and evaluate…

Computer Vision and Pattern Recognition · Computer Science 2026-04-23 Yiming Tang , Arash Lagzian , Srinivas Anumasa , Qiran Zou , Yingtao Zhu , Ye Zhang , Trang Nguyen , Yih-Chung Tham , Ehsan Adeli , Ching-Yu Cheng , Yilun Du , Dianbo Liu
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