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The clinical adoption of artificial intelligence (AI) in medical diagnostics is critically hampered by its black-box nature, which prevents clinicians from verifying the rationale behind automated decisions. To overcome this fundamental…

Reliable clinical decision support requires medical AI agents capable of safe, multi-step reasoning over structured electronic health records (EHRs). While large language models (LLMs) show promise in healthcare, existing benchmarks…

Artificial Intelligence · Computer Science 2026-01-15 Ananya Mantravadi , Shivali Dalmia , Abhishek Mukherji

Alzheimers disease (AD) is a severe neurological brain disorder. It is not curable, but earlier detection can help improve symptoms in a great deal. The machine learning based approaches are popular and well motivated models for medical…

Image and Video Processing · Electrical Eng. & Systems 2024-05-17 Lilia Lazli

The brightfield microscope is instrumental in the visual examination of both biological and physical samples at sub-millimeter scales. One key clinical application has been in cancer histopathology, where the microscopic assessment of the…

Computer Vision and Pattern Recognition · Computer Science 2020-06-03 Po-Hsuan Cameron Chen , Krishna Gadepalli , Robert MacDonald , Yun Liu , Kunal Nagpal , Timo Kohlberger , Jeffrey Dean , Greg S. Corrado , Jason D. Hipp , Martin C. Stumpe

Trauma is a significant cause of mortality and disability, particularly among individuals under forty. Traditional diagnostic methods for traumatic injuries, such as X-rays, CT scans, and MRI, are often time-consuming and dependent on…

Image and Video Processing · Electrical Eng. & Systems 2024-07-24 Liheng Jiang , Xuechun yang , Chang Yu , Zhizhong Wu , Yuting Wang

Objectives: The integration of Artificial Intelligence (AI) in healthcare promises to revolutionize patient care, diagnostics, and treatment protocols. Collaborative efforts among healthcare systems, research institutions, and industry are…

Computers and Society · Computer Science 2025-09-03 Jiancheng Ye , Michelle Ma , Malak Abuhashish

This study presents DiagCoT, a multi-stage framework that applies supervised fine-tuning to general-purpose vision-language models (VLMs) to emulate radiologists' stepwise diagnostic reasoning using only free-text reports. DiagCoT combines…

Artificial Intelligence · Computer Science 2025-09-09 Yihong Luo , Wenwu He , Zhuo-Xu Cui , Dong Liang

Medical vision-language models (Med-VLMs) have shown impressive results in tasks such as report generation and visual question answering, but they still face several limitations. Most notably, they underutilize patient metadata and lack…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Fangqi Cheng , Surajit Ray , Xiaochen Yang

Diabetic Retinopathy (DR), a leading cause of vision impairment in individuals with diabetes, affects approximately 34.6% of diabetes patients globally, with the number of cases projected to reach 242 million by 2045. Traditional DR…

Image and Video Processing · Electrical Eng. & Systems 2025-06-19 Akwasi Asare , Dennis Agyemanh Nana Gookyi , Derrick Boateng , Fortunatus Aabangbio Wulnye

Primary care providers are vital for initial triage and referrals to specialty care. In glaucoma, asymptomatic and fast progression can lead to vision loss, necessitating timely referrals to specialists. However, primary eye care providers…

Human-Computer Interaction · Computer Science 2024-07-18 Catalina Gomez , Ruolin Wang , Katharina Breininger , Corinne Casey , Chris Bradley , Mitchell Pavlak , Alex Pham , Jithin Yohannan , Mathias Unberath

Major Depressive Disorder is one of the leading causes of disability worldwide, yet its diagnosis still depends largely on subjective clinical assessments. Integrating Artificial Intelligence (AI) holds promise for developing objective,…

Artificial Intelligence · Computer Science 2026-05-01 Dorsa Macky Aleagha , Payam Zohari , Mostafa Haghir Chehreghani

Despite the success of Convolutional Neural Network-based Computer-Aided Diagnosis research, its clinical applications remain challenging. Accordingly, developing medical Artificial Intelligence (AI) fitting into a clinical environment…

Computer Vision and Pattern Recognition · Computer Science 2020-04-07 Changhee Han , Leonardo Rundo , Kohei Murao , Takafumi Nemoto , Hideki Nakayama

Each year, over 2.5 million people, most of them in developed countries, die from pneumonia [1]. Since many studies have proved pneumonia is successfully treatable when timely and correctly diagnosed, many of diagnosis aids have been…

Artificial Intelligence · Computer Science 2020-12-08 Bonaventure F. P. Dossou , Alena Iureva , Sayali R. Rajhans , Vamsi S. Pidikiti

Objectives-Geriatric clinical care is a multidisciplinary assessment designed to evaluate older patients (age 65 years and above) functional ability, physical health, and cognitive wellbeing. The majority of these patients suffer from…

Signal Processing · Electrical Eng. & Systems 2021-11-17 Avishek Choudhury , Emily Renjilian , Onur Asan

Recent Artificial Intelligence (AI) models have matched or exceeded human experts in several benchmarks of biomedical task performance, but surgical benchmarks in particular are often missing from prominent medical benchmark suites. Since…

Screening patients for clinical trial eligibility remains a manual, time-consuming, and resource-intensive process. We present a secure, scalable proof-of-concept system for Artificial Intelligence (AI)-augmented patient-trial matching that…

The rising prevalence of type 2 diabetes mellitus (T2DM) necessitates the development of predictive models for T2DM risk assessment. Artificial intelligence (AI) models are being extensively used for this purpose, but a comprehensive review…

Machine Learning · Computer Science 2023-05-29 Farida Mohsen , Hamada R. H. Al-Absi , Noha A. Yousri , Nady El Hajj , Zubair Shah

Globally, there is a substantial unmet need to diagnose various diseases effectively. The complexity of the different disease mechanisms and underlying symptoms of the patient population presents massive challenges to developing the early…

Machine Learning · Computer Science 2022-01-03 Md Manjurul Ahsan , Zahed Siddique

Diabetic Retinopathy is a critical health problem influences 100 million individuals worldwide, and these figures are expected to rise, particularly in Asia. Diabetic Retinopathy is a chronic eye disease which can lead to irreversible…

Computer Vision and Pattern Recognition · Computer Science 2019-09-27 Saket S. Chaturvedi , Kajol Gupta , Vaishali Ninawe , Prakash S. Prasad

Early diagnosis and intervention for Autism Spectrum Disorder (ASD) has been shown to significantly improve the quality of life of autistic individuals. However, diagnostics methods for ASD rely on assessments based on clinical presentation…

Image and Video Processing · Electrical Eng. & Systems 2025-03-05 Suryansh Vidya , Kush Gupta , Amir Aly , Andy Wills , Emmanuel Ifeachor , Rohit Shankar