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The ability of detecting and separating CTCs can play a key role in early cancer detection and treatment. In recent years, there has been growing interest in using deformability-based CTC separation microfilters due to their simplicity and…

Cell Behavior · Quantitative Biology 2016-01-11 Mohammad Aghaamoo , Zhifeng Zhang , Xiaolin Chen , Jie Xu

The combination of microwave and microfluidic technologies has the potential to enable wireless monitoring and interaction with bioparticles, facilitating in this way the exploration of a still largely uncharted territory at the…

Systems and Control · Electrical Eng. & Systems 2022-09-21 Cesar Palacios , Marc Jofre , Lluis Jofre , Jordi Romeu , Luis Jofre-Roca

We describe the fabrication and characterization of solid 3-dimensional electrodes in direct contact with microfluidic channels, implemented using a single photolithography step, allowing operation in high-dielectric constant media.…

Soft Condensed Matter · Physics 2013-05-16 T. W. Herling , T. Müller , L. Rajah , J. N. Skepper , M. Vendruscolo , T. P. J. Knowles

Ferrohydrodynamic microfluidics relies on magnetic field gradients to manipulate diamagnetic particles in ferrofluid-filled microenvironments. It has emerged as a promising tool for label-free manipulation of bioparticles, including their…

Systems and Control · Electrical Eng. & Systems 2025-11-03 Yuhao Zhang , Yong Teng , Kenan Song , Xianqiao Wang , Xianyan Chen , Yuhua Liu , Yiping Zhao , He Li , Leidong Mao , Yang Liu

Micromanipulations, perfusions and measurements performed using glass microelectrodes filled with an electrolyte is a conventional technique for experimental morphological and membrane electrophysiological studies at a single cell and…

Subcellular Processes · Quantitative Biology 2018-07-27 O. V. Gradov , P. A. Nasirov , A. A. Scrynnic , A. G. Jablokov

Microwave sensors integrated with microfluidic platforms can provide the size and permittivity of single cells and microparticles. Amongst the microwave sensor topologies, the planar arrangement of electrodes is a popular choice owing to…

Microcapsules are a key class of microscale materials with applications in areas ranging from personal care to biomedicine, and with increasing potential to act as extracellular matrix (ECM) models of hollow organs or tissues. Such capsules…

Spatially varying electric fields are prevalent throughout nature, such as in nanoporous materials and biological membranes, and technology, e.g, patterned electrodes and van der Waals heterostructures. While uniform fields cause free ions…

Soft Condensed Matter · Physics 2026-03-25 Anna T. Bui , Stephen J. Cox

This paper is devoted to the micro-mechanical origins of the high compressibility of brittle tubular particle assemblies. The material is extremely porous due to the presence of a large hole within the tube-shaped particle. The release of…

Materials Science · Physics 2021-10-26 M. Stasiak , G. Combe , V. Richefeu , G. Armand , J. Zghondi

Inspired by numerous lab on a chip, biomedical and bioengineering applications such as cell sorting, focusing, trapping, and filtering of particles, manipulation of micron sized particle trajectories has been of significant interest in the…

Fluid Dynamics · Physics 2026-03-18 Partha Kumar Das

We present a theoretical model and experimental demonstration of thin liquid film deformations due to a dielectric force distribution established by surface electrodes. We model the spatial electric field produced by a pair of parallel…

Soft Condensed Matter · Physics 2023-06-22 Israel Gabay , Federico Paratore , Evgeniy Boyko , Antonio Ramos , Amir D. Gat , Moran Bercovici

Cell spheroids are in vitro multicellular model systems that mimic the crowded micro-environment of biological tissues. Their mechanical characterization can provide valuable insights in how single-cell mechanics and cell-cell interactions…

Quantitative Methods · Quantitative Biology 2022-11-21 R. C. Boot , A. Roscani , L. van Buren , S. Maity , G. H. Koenderink , P. E. Boukany

In this paper, we study the stability and convergence of a decoupled and linearized mixed finite element method (FEM) for incompressible miscible displacement in a porous media whose permeability and porosity are discontinuous across some…

Numerical Analysis · Mathematics 2014-06-18 Buyang Li , Hongxing Rui , Chaoxia Yang

A microfluidic device is constructed from PDMS with a single channel having a short section that is a thin flexible membrane, in order to investigate the complex fluid-structure interaction that arises between a flowing fluid and a…

Soft Condensed Matter · Physics 2020-07-03 Debadi Chakraborty , J. Ravi Prakash , Leslie Yeo , James Friend

Within microcentrifuge devices, a microfluidic vortex separates larger particles from a heterogeneous suspension using inertial migration, a phenomenon that causes particles to migrate across streamlines. The ability to selectively capture…

Fluid Dynamics · Physics 2023-03-14 Samuel Christensen , Marcus Roper

Microfluidic channels with embedded ion permselective medium under the application of electric current are commonly used for electrokinetic processes as on-chip ion concentration polarization (ICP) and bioparticle preconcentration to…

Fluid Dynamics · Physics 2022-11-22 Barak Sabbagh , Sinwook Park , Gilad Yossifon

Capture, selective collection and flight manipulation of airborne particulate are three important functional requirements in various actively growing aerosol technology applications. Aerodynamic drag, particle inertia and dielectrophoretic…

Soft Condensed Matter · Physics 2022-03-16 Pramodt Srinivasula , Rochish M Thaokar

Microphase separation of membrane components is thought to play an important role in many physiological processes, from cell signaling to endocytosis and cellular trafficking. Here, we study how variations in the membrane composition can be…

Subcellular Processes · Quantitative Biology 2015-05-20 Pierre Sens , Matthew S. Turner

Membrane ultrafiltration (UF) is a pressure driven process allowing for the separation and enrichment of protein solutions and dispersions of nanosized microgel particles. The permeate flux and the near-membrane concentration-polarization…

Soft Condensed Matter · Physics 2015-05-19 Rafael Roa , Emiliy K. Zholkovskiy , Gerhard Nägele

The manipulation and control of microparticles through non-intrusive methods is pivotal in biomedical applications such as cell sorting and cell focusing. Although several experimental and numerical studies have been dedicated to single…

Fluid Dynamics · Physics 2023-12-20 Giancarlo Esposito , Gaetano D'Avino , Massimiliano Maria Villone