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Related papers: Advancing Multiscale Structural Mapping for Alzhei…

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Due to the rapid innovation of technology and the desire to find and employ biomarkers for neurodegenerative disease, high-dimensional data classification problems are routinely encountered in neuroimaging studies. To avoid over-fitting and…

Machine Learning · Statistics 2018-06-19 Shan Shi , Farouk Nathoo

Despite progress in deep learning for Alzheimer's disease (AD) diagnostics, models trained on structural magnetic resonance imaging (sMRI) often do not perform well when applied to new cohorts due to domain shifts from varying scanners,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-12 Zobia Batool , Diala Lteif , Vijaya B. Kolachalama , Huseyin Ozkan , Erchan Aptoula

We present a quantitative label-free imaging of mouse whole brain tissue slices with sub-micrometre resolution, employing holographic microscopy and an automated scanning platform. From the measured light field images, scattering…

Early diagnosis of Alzheimer's disease (AD) is essential in preventing the disease's progression. Therefore, detecting AD from neuroimaging data such as structural magnetic resonance imaging (sMRI) has been a topic of intense investigation…

Computer Vision and Pattern Recognition · Computer Science 2023-02-01 Maha M. Alwuthaynani , Zahraa S. Abdallah , Raul Santos-Rodriguez

Alzheimer's disease is a neurogenerative disease that alters memories, cognitive functions leading to death. Early diagnosis of the disease, by detection of the preliminary stage, called Mild Cognitive Impairment (MCI), remains a…

Image and Video Processing · Electrical Eng. & Systems 2020-12-03 Achraf Ben Miled , Taoufik Yeferny , Amira ben Rabeh

Stacking excessive layers in DNN results in highly underdetermined system when training samples are limited, which is very common in medical applications. In this regard, we present a framework capable of deriving an efficient…

Machine Learning · Computer Science 2025-03-04 Seunghun Baek , Injun Choi , Mustafa Dere , Minjeong Kim , Guorong Wu , Won Hwa Kim

The diagnosis of early stages of Alzheimer's disease (AD) is essential for timely treatment to slow further deterioration. Visualizing the morphological features for the early stages of AD is of great clinical value. In this work, a novel…

Image and Video Processing · Electrical Eng. & Systems 2021-11-29 Wen Yu , Baiying Lei , Yanyan Shen , Shuqiang Wang , Yong Liu , Zhiguang Feng , Yong Hu , Michael K. Ng

This paper explores deterioration in Alzheimers Disease using Machine Learning. Subjects were split into two datasets based on baseline diagnosis (Cognitively Normal, Mild Cognitive Impairment), with outcome of deterioration at final visit…

Machine Learning · Computer Science 2023-06-21 Henry Musto , Daniel Stamate , Ida Pu , Daniel Stahl

Computer-aided early diagnosis of Alzheimers Disease (AD) and its prodromal form, Mild Cognitive Impairment (MCI), has been the subject of extensive research in recent years. Some recent studies have shown promising results in the AD and…

Computer Vision and Pattern Recognition · Computer Science 2018-01-19 Alexander Khvostikov , Karim Aderghal , Jenny Benois-Pineau , Andrey Krylov , Gwenaelle Catheline

Alzheimer's Disease is a neurodegenerative condition characterized by dementia and impairment in neurological function. The study primarily focuses on the individuals above age 40, affecting their memory, behavior, and cognitive processes…

Computer Vision and Pattern Recognition · Computer Science 2025-01-20 Mohammad Rafsan , Tamer Oraby , Upal Roy , Sanjeev Kumar , Hansapani Rodrigo

Detection of Alzheimer's Disease (AD) from neuroimaging data such as MRI through machine learning have been a subject of intense research in recent years. Recent success of deep learning in computer vision have progressed such research…

Computer Vision and Pattern Recognition · Computer Science 2017-12-01 Marcia Hon , Naimul Khan

Background: Alzheimers disease is a progressive neurodegenerative disorder and the main cause of dementia in aging. Hippocampus is prone to changes in the early stages of Alzheimers disease. Detection and observation of the hippocampus…

Image and Video Processing · Electrical Eng. & Systems 2021-06-17 Hossein Yousefi-Banaem , Saber Malekzadeh

Understanding alterations in structural disorders in tissue or cells or building blocks, such as DNA or chromatin in the human brain, at the nano to submicron level provides us with efficient biomarkers for Alzheimers detection. Here, we…

Early clinical assessment of Alzheimer's disease relies on behavior scores that measure a subject's language, memory, and cognitive skills. On the medical imaging side, functional magnetic resonance imaging has provided invaluable insights…

Signal Processing · Electrical Eng. & Systems 2026-04-14 Javier Salazar Cavazos , Maximillian Egan , Krisanne Litinas , Benjamin Hampstead , Scott Peltier

Analysis and quantification of brain structural changes, using Magnetic resonance imaging (MRI), are increasingly used to define novel biomarkers of brain pathologies, such as Alzheimer's disease (AD). Network-based models of the brain have…

INTRODUCTION: Advanced machine learning methods might help to identify dementia risk from neuroimaging, but their accuracy to date is unclear. METHODS: We systematically reviewed the literature, 2006 to late 2016, for machine learning…

Alzheimer's disease (AD) is an irreversible neurode generative disease of the brain.The disease may causes memory loss, difficulty communicating and disorientation. For the diagnosis of Alzheimer's disease, a series of scales are often…

Image and Video Processing · Electrical Eng. & Systems 2022-01-13 Yelu Gao , Huang Huang , Lian Zhang

Alzheimer's is a brain disease that gets worse over time and affects memory, thinking, and behavior. Alzheimer's disease (AD) can be treated and managed if it is diagnosed early, which can slow the progression of symptoms and improve…

Image and Video Processing · Electrical Eng. & Systems 2024-01-09 Taymaz Akan , Sait Alp , Mohammad A. N Bhuiyanb

Alzheimer's disease is one of the most incisive illnesses among the neurodegenerative ones, and it causes a progressive decline in cognitive abilities that, in the worst cases, becomes severe enough to interfere with daily life. Currently,…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Tiziana D'Alessandro , Cristina Carmona-Duarte , Claudio De Stefano , Moises Diaz , Miguel A. Ferrer , Francesco Fontanella

Deep learning (DL) for predicting Alzheimer's disease (AD) has provided timely intervention in disease progression yet still demands attentive interpretability to explain how their DL models make definitive decisions. Recently,…

Artificial Intelligence · Computer Science 2023-10-06 Kwanseok Oh , Da-Woon Heo , Ahmad Wisnu Mulyadi , Wonsik Jung , Eunsong Kang , Kun Ho Lee , Heung-Il Suk