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Related papers: Functional Factor Modeling of Brain Connectivity

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There has been increasing interests in learning resting-state brain functional connectivity of autism disorders using functional magnetic resonance imaging (fMRI) data. The data in a standard brain template consist of over 200,000 voxel…

Methodology · Statistics 2016-03-22 Jichun Xie , Jian Kang

Knowing brain connectivity is of great importance both in basic research and for clinical applications. We are proposing a method to infer directed connectivity from zero-lag covariances of neuronal activity recorded at multiple sites. This…

Neurons and Cognition · Quantitative Biology 2018-04-10 Jonathan Schiefer , Alexander Niederbühl , Volker Pernice , Carolin Lennartz , Pierre LeVan , Jürgen Henning , Stefan Rotter

A central challenge in analyzing multivariate interactions within complex systems is to decompose how multiple inputs jointly determine an output. Existing approaches generally operate on observed probability distributions and can conflate…

Information Theory · Computer Science 2026-03-19 Clifford Bohm , Vincent R. Ragusa , Arend Hintze , Charles Ofria , Emily Dolson , Christoph Adami

Multi-dimensional functional data arises in numerous modern scientific experimental and observational studies. In this paper we focus on longitudinal functional data, a structured form of multidimensional functional data. Operating within a…

Methodology · Statistics 2019-09-20 John Shamshoian , Damla Senturk , Shafali Jeste , Donatello Telesca

High-dimensional multivariate spatial-temporal data arise frequently in a wide range of applications; however, there are relatively few statistical methods that can simultaneously deal with spatial, temporal and variable-wise dependencies…

Methodology · Statistics 2020-02-05 Elynn Y. Chen , Xin Yun , Rong Chen , Qiwei Yao

Many scientific questions in biomedical, environmental, and psychological research involve understanding the effects of multiple factors on outcomes. While factorial experiments are ideal for this purpose, randomized controlled treatment…

Methodology · Statistics 2025-12-03 Ruoqi Yu , Peng Ding

We propose modeling raw functional data as a mixture of a smooth function and a highdimensional factor component. The conventional approach to retrieving the smooth function from the raw data is through various smoothing techniques.…

Methodology · Statistics 2021-02-05 Yuan Gao , Han Lin Shang , Yanrong Yang

In recent years there has been explosive growth in the number of neuroimaging studies performed using functional Magnetic Resonance Imaging (fMRI). The field that has grown around the acquisition and analysis of fMRI data is intrinsically…

Methodology · Statistics 2009-06-22 Martin A. Lindquist

Factor analysis provides linear factors that describe relationships between individual variables of a data set. We extend this classical formulation into linear factors that describe relationships between groups of variables, where each…

Machine Learning · Statistics 2014-12-03 Arto Klami , Seppo Virtanen , Eemeli Leppäaho , Samuel Kaski

Confirmatory Factor Analysis (CFA) is a particular form of factor analysis, most commonly used in social research. In confirmatory factor analysis, the researcher first develops a hypothesis about what factors they believe are underlying…

Applications · Statistics 2019-05-15 Rui Portocarrero Sarmento , Vera Costa

Functional connectivity (FC) derived from functional magnetic resonance imaging (fMRI) data offers vital insights for understanding brain function and neurological and psychiatric disorders. Unsupervised clustering methods are desired to…

Methodology · Statistics 2025-12-04 Yixi Xu , Yi Zhao

Resting-state functional magnetic resonance imaging (rs-fMRI) is a noninvasive technique pivotal for understanding human neural mechanisms of intricate cognitive processes. Most rs-fMRI studies compute a single static functional…

Neurons and Cognition · Quantitative Biology 2025-02-25 Bishal Thapaliya , Robyn Miller , Jiayu Chen , Yu-Ping Wang , Esra Akbas , Ram Sapkota , Bhaskar Ray , Pranav Suresh , Santosh Ghimire , Vince Calhoun , Jingyu Liu

We present a computational framework for analysis and visualization of non-linear functional connectivity in the human brain from resting state functional MRI (fMRI) data for purposes of recovering the underlying network community structure…

Neural and Evolutionary Computing · Computer Science 2014-07-16 Axel Wismüller , Xixi Wang , Adora M. DSouza , Mahesh B. Nagarajan

Functional magnetic resonance imaging or functional MRI (fMRI) is a non-invasive way to assess brain activity by detecting changes associated with blood flow. In this work, we propose a full Bayesian procedure to analyze fMRI data for…

A large body of literature has shown the substantial inter-regional functional connectivity in the mammal brain. One important property remaining un-studied is the cross-time interareal connection. This paper serves to provide a tool to…

Neurons and Cognition · Quantitative Biology 2021-09-06 Ze Wang

Evaluating the functional relationships between brain regions measured with neuroimaging provides insight into how the brain is sharing information at a macro scale. Many functional connectivity methods have been developed for dynamic…

Applications · Statistics 2015-10-30 David B. Keator , Alexander Ihler

Inferring the functional specificity of brain regions from functional Magnetic Resonance Images (fMRI) data is a challenging statistical problem. While the General Linear Model (GLM) remains the standard approach for brain mapping,…

Machine Learning · Computer Science 2012-07-17 Fabian Pedregosa , Alexandre Gramfort , Gaël Varoquaux , Bertrand Thirion , Christophe Pallier , Elodie Cauvet

Non-invasive measurements of the human brain using magnetic resonance imaging (MRI) have significantly improved our understanding the brain's network organization by enabling measurement of anatomical connections between brain regions…

Applications · Statistics 2025-12-10 Keshav Motwani , Ali Shojaie , Ariel Rokem , Eardi Lila

This paper develops an inferential theory for high-dimensional matrix-variate factor models with missing observations. We propose an easy-to-use all-purpose method that involves two straightforward steps. First, we perform principal…

Methodology · Statistics 2025-03-26 Yongxia Zhang , Jinwen Liang , Liwen Xu , Keming Yu , Maozai Tian

We propose a novel two-phase approach to functional network estimation of multi-subject functional Magnetic Resonance Imaging (fMRI) data, which applies model-based image segmentation to determine a group-representative connectivity map. In…

Computation · Statistics 2018-09-05 Aditi Iyer , Bingjing Tang , Vinayak Rao , Nan Kong