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Osteoarthritis (OA) is the most common musculoskeletal disease, with knee OA (KOA) being one of the leading causes of disability and a significant economic burden. Predicting KOA progression is crucial for improving patient outcomes,…

Machine Learning · Computer Science 2025-04-09 Khanh Nguyen , Huy Hoang Nguyen , Egor Panfilov , Aleksei Tiulpin

Knee osteoarthritis (OA) is the most common musculoskeletal disease without a cure, and current treatment options are limited to symptomatic relief. Prediction of OA progression is a very challenging and timely issue, and it could, if…

Computer Vision and Pattern Recognition · Computer Science 2019-05-07 Aleksei Tiulpin , Stefan Klein , Sita M. A. Bierma-Zeinstra , Jérôme Thevenot , Esa Rahtu , Joyce van Meurs , Edwin H. G. Oei , Simo Saarakkala

Osteoarthritis (OA) is the most prevalent chronic joint disease worldwide, where knee OA takes more than 80% of commonly affected joints. Knee OA is not a curable disease yet, and it affects large columns of patients, making it costly to…

Artificial Intelligence · Computer Science 2022-12-23 Soheyla Amirian , Husam Ghazaleh , Mehdi Assefi , Hilal Maradit Kremers , Hamid R. Arabnia , Johannes F. Plate , Ahmad P. Tafti

Knee osteoarthritis (OA) is very common progressive and degenerative musculoskeletal disease worldwide creates a heavy burden on patients with reduced quality of life and also on society due to financial impact. Therefore, any attempt to…

Image and Video Processing · Electrical Eng. & Systems 2020-05-26 Neslihan Bayramoglu , Miika T. Nieminen , Simo Saarakkala

Knee Osteoarthritis (OA) is a destructive joint disease identified by joint stiffness, pain, and functional disability concerning millions of lives across the globe. It is generally assessed by evaluating physical symptoms, medical history,…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Rohit Kumar Jain , Prasen Kumar Sharma , Sibaji Gaj , Arijit Sur , Palash Ghosh

Knee osteoarthritis (OA) is the most common musculoskeletal disorder. OA diagnosis is currently conducted by assessing symptoms and evaluating plain radiographs, but this process suffers from subjectivity. In this study, we present a new…

Computer Vision and Pattern Recognition · Computer Science 2017-10-31 Aleksei Tiulpin , Jérôme Thevenot , Esa Rahtu , Petri Lehenkari , Simo Saarakkala

Knee Osteoarthritis (KOA) is a highly prevalent chronic musculoskeletal condition with no currently available treatment. The manifestation of KOA is heterogeneous and prediction of its progression is challenging. Current literature suggests…

Image and Video Processing · Electrical Eng. & Systems 2023-07-04 Egor Panfilov , Simo Saarakkala , Miika T. Nieminen , Aleksei Tiulpin

Diagnosing knee osteoarthritis (OA) early is crucial for managing symptoms and preventing further joint damage, ultimately improving patient outcomes and quality of life. In this paper, a bioimpedance-based diagnostic tool that combines…

Signal Processing · Electrical Eng. & Systems 2025-05-06 Jamal Al-Nabulsi , Mohammad Al-Sayed Ahmad , Baraa Hasaneiah , Fayhaa AlZoubi

Knee osteoarthritis (OA) is a widespread chronic condition that impairs mobility and diminishes quality of life. Despite the proven benefits of exercise therapy and patient education in managing the OA symptoms pain and functional…

Machine Learning · Computer Science 2024-10-17 M. Rafiei , S. Das , M. Bakhtiari , E. M. Roos , S. T. Skou , D. T. Grønne , J. Baumbach , L. Baumbach

Knee osteoarthritis (OA) is the most common musculoskeletal disease in the world. In primary healthcare, knee OA is diagnosed using clinical examination and radiographic assessment. Osteoarthritis Research Society International (OARSI)…

Image and Video Processing · Electrical Eng. & Systems 2019-07-19 Aleksei Tiulpin , Simo Saarakkala

Osteoarthritis (OA) is a common musculoskeletal condition typically diagnosed from radiographic assessment after clinical examination. However, a visual evaluation made by a practitioner suffers from subjectivity and is highly dependent on…

Computer Vision and Pattern Recognition · Computer Science 2017-04-07 Aleksei Tiulpin , Jérôme Thevenot , Esa Rahtu , Simo Saarakkala

Knee osteoarthritis (OA) is the most common osteoarthritis and a leading cause of disability. Cartilage defects are regarded as major manifestations of knee OA, which are visible by magnetic resonance imaging (MRI). Thus early detection and…

Image and Video Processing · Electrical Eng. & Systems 2022-01-13 Zixu Zhuang , Liping Si , Sheng Wang , Kai Xuan , Xi Ouyang , Yiqiang Zhan , Zhong Xue , Lichi Zhang , Dinggang Shen , Weiwu Yao , Qian Wang

Medical imaging plays a crucial role in assessing knee osteoarthritis (OA) risk by enabling early detection and disease monitoring. Recent machine learning methods have improved risk estimation (i.e., predicting the likelihood of disease…

Computer Vision and Pattern Recognition · Computer Science 2025-06-18 David Butler , Adrian Hilton , Gustavo Carneiro

Osteoarthritis (OA) is a multifaceted joint disease which poses significant socioeconomic burdens and remains a significant clinical challenge. Evidence suggests that structural and mechanical changes in subchondral bone influence the…

Knee Osteoarthritis (OA) is a common musculoskeletal disorder in the United States. When diagnosed at early stages, lifestyle interventions such as exercise and weight loss can slow OA progression, but at later stages, only an invasive…

Image and Video Processing · Electrical Eng. & Systems 2020-02-26 Aniket A. Tolpadi , Jinhee J. Lee , Valentina Pedoia , Sharmila Majumdar

Knee osteoarthritis (OA) is one of the most widespread and burdensome health problems [1-4]. Total knee replacement (TKR) may be offered as treatment for end-stage knee OA. Nevertheless, TKR is an invasive procedure involving prosthesis…

Image and Video Processing · Electrical Eng. & Systems 2025-11-20 Zhisen Hu , Dominic Cullen , David S. Johnson , Aleksei Tiulpin , Timothy F. Cootes , Claudia Lindner

Osteoarthritis (OA) is one of the major health issues among the elderly population. MRI is the most popular technology to observe and evaluate the progress of OA course. However, the extreme labor cost of MRI analysis makes the process…

Computer Vision and Pattern Recognition · Computer Science 2021-02-17 Boyu Zhang , Yingtao Zhang , H. D. Cheng , Min Xian , Shan Gai , Olivia Cheng , Kuan Huang

Accurate prediction of knee osteoarthritis (KOA) progression from structural MRI has a potential to enhance disease understanding and support clinical trials. Prior art focused on manually designed imaging biomarkers, which may not fully…

Image and Video Processing · Electrical Eng. & Systems 2024-08-07 Egor Panfilov , Simo Saarakkala , Miika T. Nieminen , Aleksei Tiulpin

The aim of this study was to investigate the influence of MRI and patient data on the prediction of knee osteoarthritis (OA) incidence using different deep learning architectures. Knee OA incidence within 24 months was predicted using the…

Medical Physics · Physics 2022-09-05 Anastasis Alexopoulos , Jukka Hirvasniemi , Nazli Tümer

Knee osteoarthritis (KOA) is a disease that impairs knee function and causes pain. A radiologist reviews knee X-ray images and grades the severity level of the impairments according to the Kellgren and Lawrence grading scheme; a five-point…

Image and Video Processing · Electrical Eng. & Systems 2019-08-26 Jaynal Abedin , Joseph Antony , Kevin McGuinness , Kieran Moran , Noel E O'Connor , Dietrich Rebholz-Schuhmann , John Newell
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