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While variational quantum algorithms (VQAs) have demonstrated considerable success in unconstrained optimization, their application to constrained combinatorial problems face a trade-off. Penalty-based methods, despite their circuit…

Quantum Physics · Physics 2026-03-09 Hui-Min Li , Yuan-Liang Han , Zhi-Xi Wang , Shao-Ming Fei

Translating a general quantum circuit on a specific hardware topology with a reduced set of available gates, also known as transpilation, comes with a substantial increase in the length of the equivalent circuit. Due to decoherence, the…

Quantum Physics · Physics 2025-10-15 Bodo Rosenhahn , Tobias J. Osborne , Christoph Hirche

The variational quantum eigensolver (VQE) is currently the flagship algorithm for solving electronic structure problems on near-term quantum computers. This hybrid quantum/classical algorithm involves implementing a sequence of…

Gate-model quantum computers provide an experimentally implementable architecture for near term quantum computations. To design a reduced quantum circuit that can simulate a high complexity reference quantum circuit, an optimization should…

Quantum Physics · Physics 2019-09-04 Laszlo Gyongyosi , Sandor Imre

This work presents an optimization method for the synthesis of finite state machines. The focus is on the reduction in the on-chip area and the cost of the circuit. A list of finite state machines from MCNC91 benchmark circuits have been…

Neural and Evolutionary Computing · Computer Science 2024-01-03 Noor Ullah , Khawaja M. Yahya , Irfan Ahmed

Developing optimal strategies to calibrate quantum processors for high-fidelity operation is one of the outstanding challenges in quantum computing today. Here, we demonstrate multiple examples of high-fidelity operations achieved using a…

Portfolio optimization is a cornerstone of financial decision-making, traditionally relying on classical algorithms to balance risk and return. Recent advances in quantum computing offer a promising alternative, leveraging quantum…

Quantum Physics · Physics 2025-11-27 Vicente P. Soloviev , Michal Krompiec

Near-term quantum computers will be limited in the number of qubits on which they can process information as well as the depth of the circuits that they can coherently carry out. To-date, experimental demonstrations of algorithms such as…

Chemical Physics · Physics 2023-10-18 Joel Bierman , Yingzhou Li , Jianfeng Lu

Digital quantum simulation is a promising application for quantum computers. Their free programmability provides the potential to simulate the unitary evolution of any many-body Hamiltonian with bounded spectrum by discretizing the time…

Quantum Physics · Physics 2021-09-15 Adrien Bolens , Markus Heyl

Combinatorial optimization on near-term quantum devices is a promising path to demonstrating quantum advantage. However, the capabilities of these devices are constrained by high noise or error rates. In this paper, we propose an iterative…

Quantum Physics · Physics 2022-05-12 Xiaoyuan Liu , Anthony Angone , Ruslan Shaydulin , Ilya Safro , Yuri Alexeev , Lukasz Cincio

Quantum control plays an irreplaceable role in practical use of quantum computers. However, some challenges have to be overcome to find more suitable and diverse control parameters. We propose a promising and generalizable…

Quantum Physics · Physics 2023-09-29 Meng-Yun Mao , Zheng Cheng , Yan Xia , Andrzej M. Oleś , Wen-Long You

The quantum approximate optimization algorithm (QAOA) is a quantum heuristic for combinatorial optimization that has been demonstrated to scale better than state-of-the-art classical solvers for some problems. For a given problem instance,…

Quantum Physics · Physics 2026-02-23 Tianyi Hao , Zichang He , Ruslan Shaydulin , Jeffrey Larson , Marco Pistoia

Error mitigation is essential for near-term quantum devices, and two promising techniques are universal frame randomization and Randomized Compilation. These methods insert random twirling gates into a circuit to reduce errors while…

Quantum Physics · Physics 2025-11-04 Rachel E. Johnson , Joshua A. Job , Steve Adachi

Combinatorial optimization is a promising application for near-term quantum computers, however, identifying performant algorithms suited to noisy quantum hardware remains as an important goal to potentially realizing quantum computational…

Quantum Physics · Physics 2025-04-01 Titus D. Morris , Ananth Kaushik , Martin Roetteler , Phillip C. Lotshaw

We introduce a novel quantum optimization paradigm: the Fixed-Parameter-Count Quantum Approximate Optimization Algorithm (FPC-QAOA). It is a scalable variational framework that maintains a constant number of trainable parameters regardless…

We present a method to split quantum circuits of variational quantum algorithms (VQAs) to allow for parallel training and execution, that maximally exploits the limited number of qubits in hardware to solve large problem instances. We apply…

Quantum Physics · Physics 2023-04-07 Michele Cattelan , Sheir Yarkoni

We introduce a variational quantum algorithm to solve unconstrained black box binary optimization problems, i.e., problems in which the objective function is given as black box. This is in contrast to the typical setting of quantum…

We propose a method for finding approximate compilations of quantum unitary transformations, based on techniques from policy gradient reinforcement learning. The choice of a stochastic policy allows us to rephrase the optimization problem…

Quantum Physics · Physics 2022-09-14 David A. Herrera-Martí

Optimizing the mRNA codon has an essential impact on gene expression for a specific target protein. It is an NP-hard problem; thus, exact solutions to such optimization problems become computationally intractable for realistic problem sizes…

Quantum Physics · Physics 2024-05-13 Hongfeng Zhang , Aritra Sarkar , Koen Bertels

We investigate automated in situ optimization of the potential landscape in a quantum point contact device, using a $3 \times 3$ gate array patterned atop the constriction. Optimization is performed using the covariance matrix adaptation…