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Early multiple sclerosis (MS) disability progression prediction is challenging due to disease heterogeneity. This work predicts 48- and 72-week disability using sparse baseline clinical data and 12 weeks of daily digital Floodlight data…

Machine Learning · Computer Science 2025-06-19 Maxime Usdin , Lito Kriara , Licinio Craveiro

Unique identification of multiple sclerosis (MS) white matter lesions (WMLs) is important to help characterize MS progression. WMLs are routinely identified from magnetic resonance images (MRIs) but the resultant total lesion load does not…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Carlos A. Rivas , Jinwei Zhang , Shuwen Wei , Samuel W. Remedios , Aaron Carass , Jerry L. Prince

Suppression of disability progression is an important goal in the treatment of multiple sclerosis (MS). Randomized clinical trials in MS frequently use the time to the first confirmed disability progression (CDP) on the ordinal Expanded…

Applications · Statistics 2021-11-04 Alexandra Būhler

Trustworthy artificial intelligence (AI) is essential in healthcare, particularly for high-stakes tasks like medical image segmentation. Explainable AI and uncertainty quantification significantly enhance AI reliability by addressing key…

Skin lesion identification is a key step toward dermatological diagnosis. When describing a skin lesion, it is very important to note its body site distribution as many skin diseases commonly affect particular parts of the body. To exploit…

Computer Vision and Pattern Recognition · Computer Science 2022-03-24 Haofu Liao , Jiebo Luo

Segmentation of both large and small white matter hyperintensities/lesions in brain MR images is a challenging task which has drawn much attention in recent years. We propose a multi-scale aggregation model framework to deal with…

Computer Vision and Pattern Recognition · Computer Science 2019-02-28 Hongwei Li , Jianguo Zhang , Mark Muehlau , Jan Kirschke , Bjoern Menze

Multiple Sclerosis (MS) is a chronic neurological condition characterized by the development of lesions in the white matter of the brain. T2-fluid attenuated inversion recovery (FLAIR) brain magnetic resonance imaging (MRI) provides…

Image and Video Processing · Electrical Eng. & Systems 2022-09-01 Jueqi Wang , Derek Berger , Erin Mazerolle , Jean-Alexis Delamer , Jacob Levman

Functional magnetic resonance imaging (fMRI) data contain complex spatiotemporal dynamics, thus researchers have developed approaches that reduce the dimensionality of the signal while extracting relevant and interpretable dynamics. Models…

Computer Vision and Pattern Recognition · Computer Science 2022-05-30 Eloy Geenjaar , Amrit Kashyap , Noah Lewis , Robyn Miller , Vince Calhoun

Purpose: Repeated brain MRI scans are performed in many clinical scenarios, such as follow up of patients with tumors and therapy response assessment. In this paper, the authors show an approach to utilize former scans of the patient for…

Medical Physics · Physics 2017-08-28 Lior Weizman , Yonina C. Eldar , Dafna Ben Bashat

Accurate segmentation of skin lesion from dermoscopic images is a crucial part of computer-aided diagnosis of melanoma. It is challenging due to the fact that dermoscopic images from different patients have non-negligible lesion variation,…

Computer Vision and Pattern Recognition · Computer Science 2020-02-21 Xiaohong Wang , Xudong Jiang , Henghui Ding , Jun Liu

Despite recent improvements in medical image segmentation, the ability to generalize across imaging contrasts remains an open issue. To tackle this challenge, we implement Feature-wise Linear Modulation (FiLM) to leverage physics knowledge…

Image and Video Processing · Electrical Eng. & Systems 2020-06-05 Olivier Vincent , Charley Gros , Joseph Paul Cohen , Julien Cohen-Adad

Medical image segmentation is vital to the area of medical imaging because it enables professionals to more accurately examine and understand the information offered by different imaging modalities. The technique of splitting a medical…

Image and Video Processing · Electrical Eng. & Systems 2024-09-01 Aitik Gupta , Joydip Dhar

High-dimensional linear classifiers, such as the support vector machine (SVM) and distance weighted discrimination (DWD), are commonly used in biomedical research to distinguish groups of subjects based on a large number of features.…

Methodology · Statistics 2017-10-20 Tianmeng Lyu , Eric F. Lock , Lynn E. Eberly

Multiple sclerosis (MS) is an inflammatory and neurodegenerative disease characterized by diffuse and focal areas of tissue loss. Conventional MRI techniques such as T1-weighted and T2-weighted scans are generally used in the diagnosis and…

Skin cancer is one of the deadliest diseases and has a high mortality rate if left untreated. The diagnosis generally starts with visual screening and is followed by a biopsy or histopathological examination. Early detection can aid in…

Computer Vision and Pattern Recognition · Computer Science 2023-10-12 Mahapara Khurshid , Mayank Vatsa , Richa Singh

Even though convolutional neural networks (CNNs) are driving progress in medical image segmentation, standard models still have some drawbacks. First, the use of multi-scale approaches, i.e., encoder-decoder architectures, leads to a…

Computer Vision and Pattern Recognition · Computer Science 2020-02-18 Ashish Sinha , Jose Dolz

The automated detection of cortical lesions (CLs) in patients with multiple sclerosis (MS) is a challenging task that, despite its clinical relevance, has received very little attention. Accurate detection of the small and scarce lesions…

Image and Video Processing · Electrical Eng. & Systems 2020-08-18 Francesco La Rosa , Erin S Beck , Ahmed Abdulkadir , Jean-Philippe Thiran , Daniel S Reich , Pascal Sati , Meritxell Bach Cuadra

Machine learning analysis of longitudinal neuroimaging data is typically based on supervised learning, which requires a large number of ground-truth labels to be informative. As ground-truth labels are often missing or expensive to obtain…

Machine Learning · Computer Science 2021-06-29 Qingyu Zhao , Zixuan Liu , Ehsan Adeli , Kilian M. Pohl

Chronic wounds such as diabetic foot ulcers and pressure injuries require accurate tissue-level assessment to guide treatment planning and monitor healing progression. While deep learning methods have advanced automated wound analysis, most…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Muhammad Ashad Kabir , Rabin Dulal

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS) that results in focal injury to the grey and white matter. The presence of white matter lesions biases morphometric analyses such as…

Computer Vision and Pattern Recognition · Computer Science 2019-09-09 Hao Xiong , Chaoyue Wang , Dacheng Tao , Michael Barnett , Chenyu Wang
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