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To index the increasing volume of data, modern data indexes are typically stored on SSDs and cached in DRAM. However, searching such an index has resulted in significant I/O traffic due to limited access locality and inefficient cache…

Hardware Architecture · Computer Science 2024-08-05 Yun-Chih Chen , Yuan-Hao Chang , Tei-Wei Kuo

Multiplication of a sparse matrix to a dense matrix (SpDM) is widely used in many areas like scientific computing and machine learning. However, existing works under-look the performance optimization of SpDM on modern many-core…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-06-01 Shaohuai Shi , Qiang Wang , Xiaowen Chu

In this paper, we present FLiMS, a highly-efficient and simple parallel algorithm for merging two sorted lists residing in banked and/or wide memory. On FPGAs, its implementation uses fewer hardware resources than the state-of-the-art…

Hardware Architecture · Computer Science 2022-03-08 Philippos Papaphilippou , Wayne Luk , Chris Brooks

As the structural databases continue to expand, efficient methods are required to search similar structures of the query structure from the database. There are many previous works about comparing protein 3D structures and scanning the…

Databases · Computer Science 2011-02-16 Gook-Pil Roh , Seung-won Hwang , Byoung-Kee Yi

Quantitative proteomics plays a central role in uncovering regulatory mechanisms, identifying disease biomarkers, and guiding the development of precision therapies. These insights are often obtained through complex Bayesian models, whose…

Quantitative Methods · Quantitative Biology 2025-09-11 Matthew Carter , Lee Devlin , Alexander Philips , Edward Pyzer-Knapp , Paul Spirakis , Simon Maskell

As the amount of data produced in society continues to grow at an exponential rate, modern applications are incurring significant performance and energy penalties due to high data movement between the CPU and memory/storage. While…

Hardware Architecture · Computer Science 2024-03-12 Ryan Wong , Nikita Kim , Kevin Higgs , Sapan Agarwal , Engin Ipek , Saugata Ghose , Ben Feinberg

Our goal in this dissertation is to provide tools, programming models, and system support for PIM architectures (with a focus on DRAM-based solutions), to ease the adoption of PIM in current and future systems. To this end, we make at least…

Hardware Architecture · Computer Science 2025-08-28 Geraldo F. Oliveira

Efficient Nearest Neighbor (NN) search in high-dimensional spaces is a foundation of many multimedia retrieval systems. A common approach is to rely on Product Quantization, which allows the storage of large vector databases in memory and…

Computer Vision and Pattern Recognition · Computer Science 2019-11-18 Fabien André , Anne-Marie Kermarrec , Nicolas Le Scouarnec

Accurate Speed-of-Sound (SoS) reconstruction from acoustic waveforms is a cornerstone of ultrasound computed tomography (USCT), enabling quantitative velocity mapping that reveals subtle anatomical details and pathological variations often…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Yujia Wu , Shuoqi Chen , Shiru Wang , Yucheng Tang , Petr Bruza , Geoffrey P. Luke

Designing protein sequences that fold into a target 3-D structure, termed as the inverse folding problem, is central to protein engineering. However, it remains challenging due to the vast sequence space and the importance of local…

Quantitative Methods · Quantitative Biology 2026-03-17 Sazan Mahbub , Souvik Kundu , Eric P. Xing

Purpose: Common dense stereo Simultaneous Localization and Mapping (SLAM) approaches in Minimally Invasive Surgery (MIS) require high-end parallel computational resources for real-time implementation. Yet, it is not always feasible since…

Robotics · Computer Science 2023-12-27 Jingwei Song , Ray Zhang , Qiuchen Zhu , Jianyu Lin , Maani Ghaffari

The surging demand for GPUs in datacenters for machine learning (ML) has made efficient GPU utilization crucial. However, meeting the diverse needs of ML models while optimizing resource usage is challenging. To enable transparent,…

Extracting actionable information rapidly from data produced by instruments such as the Linac Coherent Light Source (LCLS-II) and Advanced Photon Source Upgrade (APS-U) is becoming ever more challenging due to high (up to TB/s) data rates.…

Small objects detection is a challenging task in computer vision due to its limited resolution and information. In order to solve this problem, the majority of existing methods sacrifice speed for improvement in accuracy. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2018-11-28 Guimei Cao , Xuemei Xie , Wenzhe Yang , Quan Liao , Guangming Shi , Jinjian Wu

Nearest Neighbor Search (NNS) has recently drawn a rapid increase of interest due to its core role in managing high-dimensional vector data in data science and AI applications. The interest is fueled by the success of neural embedding,…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-02-01 Zhen Peng , Minjia Zhang , Kai Li , Ruoming Jin , Bin Ren

High-level synthesis (HLS) has received significant attention in recent years, improving programmability for FPGAs. PolyMage is a domain-specific language (DSL) for image processing pipelines that also has a HLS backend to translate the…

Hardware Architecture · Computer Science 2018-12-20 Vinamra Benara , Ziaul Choudhury , Suresh Purini , Uday Bondhugula

Machine learning algorithms, such as Support Vector Machine (SVM) and Deep Neural Network (DNN), have gained a lot of interests recently. When training a machine learning algorithm, randomly shuffle all the training data can improve the…

Performance · Computer Science 2018-10-11 Zhi-Lin Ke , Hsiang-Yun Cheng , Chia-Lin Yang

This paper describes the numerical implementation in a high-performance computing environment of an open-source library for model order reduction in fluid dynamics. This library, called pyLOM, contains the algorithms of proper orthogonal…

Hybrid Solid-State Drives (SSDs), which integrate several types of flash cells (e.g., single-level cell (SLC) and multiple-level cell (MLC)) in a single drive and enable them to convert between each other, are designed to deliver both high…

Hardware Architecture · Computer Science 2025-03-18 Qian Wei , Yi Li , Zehao Chen , Zhaoyan Shen , Dongxiao Yu , Bingzhe Li

Neural architecture search (NAS) is a promising technique to design efficient and high-performance deep neural networks (DNNs). As the performance requirements of ML applications grow continuously, the hardware accelerators start playing a…

Computer Vision and Pattern Recognition · Computer Science 2021-08-03 Guihong Li , Sumit K. Mandal , Umit Y. Ogras , Radu Marculescu