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Systems biology and systems neurophysiology in particular have recently emerged as powerful tools for a number of key applications in the biomedical sciences. Nevertheless, such models are often based on complex combinations of multiscale…

Neural and Evolutionary Computing · Computer Science 2022-09-27 Matteo Ferrante , Andera Duggento , Nicola Toschi

Deep learning methods have gained considerable interest in the numerical solution of various partial differential equations (PDEs). One particular focus is physics-informed neural networks (PINN), which integrate physical principles into…

Dynamical Systems · Mathematics 2023-12-19 Xi'an Li , Jiaxin Deng , Jinran Wu , Shaotong Zhang , Weide Li , You-Gan Wang

Although physics-informed neural networks (PINNs) have shown great potential in dealing with nonlinear partial differential equations (PDEs), it is common that PINNs will suffer from the problem of insufficient precision or obtaining…

Machine Learning · Computer Science 2024-10-07 Feilong Jiang , Xiaonan Hou , Min Xia

The accurate solution of nonlinear hyperbolic partial differential equations (PDEs) remains challenging due to steep gradients, discontinuities, and multiscale structures that make conventional solvers computationally demanding.…

Machine Learning · Computer Science 2025-12-02 Saif Ur Rehman , Wajid Yousuf

We present a Physics-Informed Neural Network (PINN) to simulate the thermochemical evolution of a composite material on a tool undergoing cure in an autoclave. In particular, we solve the governing coupled system of differential equations…

Machine Learning · Computer Science 2021-06-16 Sina Amini Niaki , Ehsan Haghighat , Trevor Campbell , Anoush Poursartip , Reza Vaziri

Physics-Informed Neural Network (PINN) is a deep learning framework that integrates the governing equations underlying data into a loss function. In this study, we consider the problem of estimating state variables and parameters in…

Symbolic Computation · Computer Science 2025-08-07 Mizuka Komatsu

Mathematical models in neural networks are powerful tools for solving complex differential equations and optimizing their parameters; that is, solving the forward and inverse problems, respectively. A forward problem predicts the output of…

Machine Learning · Computer Science 2025-07-29 Aarush Gupta , Kendric Hsu , Syna Mathod

This paper explores the difficulties in solving partial differential equations (PDEs) using physics-informed neural networks (PINNs). PINNs use physics as a regularization term in the objective function. However, a drawback of this approach…

Machine Learning · Computer Science 2023-06-21 Shamsulhaq Basir

We provide an approach enabling one to employ physics-informed neural networks (PINNs) for uncertainty quantification. Our approach is applicable to systems where observations are scarce (or even lacking), these being typical situations…

Data Analysis, Statistics and Probability · Physics 2024-08-12 Milad Panahi , Giovanni Michele Porta , Monica Riva , Alberto Guadagnini

Physics-informed neural networks (PINNs) have shown promising potential for solving partial differential equations (PDEs) using deep learning. However, PINNs face training difficulties for evolutionary PDEs, particularly for dynamical…

Neural and Evolutionary Computing · Computer Science 2023-12-25 Siqi Chen , Bin Shan , Ye Li

Recent work in scientific machine learning has developed so-called physics-informed neural network (PINN) models. The typical approach is to incorporate physical domain knowledge as soft constraints on an empirical loss function and use…

Machine Learning · Computer Science 2021-11-12 Aditi S. Krishnapriyan , Amir Gholami , Shandian Zhe , Robert M. Kirby , Michael W. Mahoney

Physics-informed neural networks (PINNs) have demonstrated promise as a framework for solving forward and inverse problems involving partial differential equations. Despite recent progress in the field, it remains challenging to quantify…

Machine Learning · Computer Science 2025-11-14 Bruno Jacob , Ashish S. Nair , Amanda A. Howard , Jan Drgona , Panos Stinis

Partial Differential Equations (PDEs) are integral to modeling many scientific and engineering problems. Physics-informed Neural Networks (PINNs) have emerged as promising tools for solving PDEs by embedding governing equations into the…

Numerical Analysis · Mathematics 2025-01-07 Farinaz Mostajeran , Salah A Faroughi

Achieving clean combustion systems is crucial in terms of solving environmental impacts, decarbonization needs and sustainability matters. Traditional combustion modeling techniques via computational fluid dynamics with accurate chemical…

Fluid Dynamics · Physics 2025-09-11 Mahmood Mousavi , Caleb Caldwell , Jacob Baltes , Muteb Aljasem , Bok Jik Lee

Differential equations are involved in modeling many engineering problems. Many efforts have been devoted to solving differential equations. Due to the flexibility of neural networks, Physics Informed Neural Networks (PINNs) have recently…

Computational Engineering, Finance, and Science · Computer Science 2025-09-22 Siyuan Yang , Cheng Song , Zhilu Lai , Wenjia Wang

Physics-Informed Neural Networks (PINNs) have become a kind of attractive machine learning method for obtaining solutions of partial differential equations (PDEs). Training PINNs can be seen as a semi-supervised learning task, in which only…

Machine Learning · Computer Science 2022-10-25 Jia Guo , Haifeng Wang , Chenping Hou

Physics-Informed Neural Networks (PINNs) are a class of deep learning neural networks that learn the response of a physical system without any simulation data, and only by incorporating the governing partial differential equations (PDEs) in…

Machine Learning · Computer Science 2023-12-19 Rini J. Gladstone , Mohammad A. Nabian , N. Sukumar , Ankit Srivastava , Hadi Meidani

Physics-Informed Neural Networks (PINNs) incorporate physics into neural networks by embedding partial differential equations (PDEs) into their loss function. Despite their success in learning the underlying physics, PINN models remain…

Machine Learning · Computer Science 2026-03-04 Alberto Miño Calero , Luis Salamanca , Konstantinos E. Tatsis

Inverse problems involving differential equations often require identifying unknown parameters or functions from data. Existing approaches, such as Physics-Informed Neural Networks (PINNs), Universal Differential Equations (UDEs) and…

Machine Learning · Computer Science 2025-05-23 Shalev Manor , Mohammad Kohandel

Physics-Informed Neural Networks (PINNs) have emerged as a key tool in Scientific Machine Learning since their introduction in 2017, enabling the efficient solution of ordinary and partial differential equations using sparse measurements.…

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