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The use of Deep Learning (DL) based methods in medical histopathology images have been one of the most sought after solutions to classify, segment, and detect diseased biopsy samples. However, given the complex nature of medical datasets…

Accurate clinical diagnosis requires extensive domain knowledge and complex clinical reasoning capabilities. Although large language models (LLMs) hold great potential for clinical reasoning, their high computational and memory requirements…

Quality assessment of prenatal ultrasonography is essential for the screening of fetal central nervous system (CNS) anomalies. The interpretation of fetal brain structures is highly subjective, expertise-driven, and requires years of…

AIM To analyse the performance of a deep-learning (DL) algorithm currently deployed as diagnostic decision support software in two NHS Trusts used to identify normal chest x-rays in active clinical pathways. MATERIALS AND METHODS A DL…

While enjoying the great achievements brought by deep learning (DL), people are also worried about the decision made by DL models, since the high degree of non-linearity of DL models makes the decision extremely difficult to understand.…

Vertebral fracture grading classifies the severity of vertebral fractures, which is a challenging task in medical imaging and has recently attracted Deep Learning (DL) models. Only a few works attempted to make such models…

Prenatal ultrasound is the cornerstone for detecting congenital anomalies of the kidneys and urinary tract, but diagnosis is limited by operator dependence and suboptimal imaging conditions. We sought to assess the performance of a…

Privacy-preserving medical decision support for kidney disease requires localized deployment of large language models (LLMs) while maintaining clinical reasoning capabilities. Current solutions face three challenges: 1) Cloud-based LLMs…

Background: MRI is the modality of choice for cartilage imaging; however, its diagnostic performance is variable and significantly lower than the gold standard diagnostic knee arthroscopy. In recent years, deep learning has been used to…

There is an increasing interest in the use of Deep Learning (DL) based methods as a supporting analytical framework in oncology. However, most direct applications of DL will deliver models with limited transparency and explainability, which…

Kidney abnormality detection is required for all preclinical drug development. It involves a time-consuming and costly examination of hundreds to thousands of whole-slide images per drug safety study, most of which are normal, to detect any…

Deep neural network (DNN) models for retinopathy have estimated predictive accuracies in the mid-to-high 90%. However, the following aspects remain unaddressed: State-of-the-art models are complex and require substantial computational…

Offloading footwear helps prevent and treat diabetic foot ulcers (DFUs) by lowering plantar pressure (PP), yet prescription decisions remain fragmented: feature selection varies, personalization is limited, and evaluation practices differ.…

We proposed a deep learning method for interpretable diabetic retinopathy (DR) detection. The visual-interpretable feature of the proposed method is achieved by adding the regression activation map (RAM) after the global averaging pooling…

The robust and automated determination of crystal symmetry is of utmost importance in material characterization and analysis. Recent studies have shown that deep learning (DL) methods can effectively reveal the correlations between X-ray or…

Deep learning (DL) has gained popularity in recent years as an effective tool for classifying the current health and predicting the future of industrial equipment. However, most DL models have black-box components with an underlying…

Prototype-based methods use interpretable representations to address the black-box nature of deep learning models, in contrast to post-hoc explanation methods that only approximate such models. We propose the Neural Prototype Tree…

Purpose: Pelvic bone segmentation in CT has always been an essential step in clinical diagnosis and surgery planning of pelvic bone diseases. Existing methods for pelvic bone segmentation are either hand-crafted or semi-automatic and…

Many renal cancers are incidentally found on non-contrast CT (NCCT) images. On contrast-enhanced CT (CECT) images, most kidney tumors, especially renal cancers, have different intensity values compared to normal tissues. However, on NCCT…

As the global population ages, the incidence of Chronic Kidney Disease (CKD) is rising. CKD often remains asymptomatic until advanced stages, which significantly burdens both the healthcare system and patient quality of life. This research…