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Based on the Denoising Diffusion Probabilistic Model (DDPM), medical image segmentation can be described as a conditional image generation task, which allows to compute pixel-wise uncertainty maps of the segmentation and allows an implicit…

Image and Video Processing · Electrical Eng. & Systems 2022-11-01 Xutao Guo , Yanwu Yang , Chenfei Ye , Shang Lu , Yang Xiang , Ting Ma

Domain generalization (DG) is a difficult transfer learning problem aiming to learn a generalizable model for unseen domains. Recent foundation models (FMs) are robust to many distribution shifts and, therefore, should substantially improve…

Computer Vision and Pattern Recognition · Computer Science 2022-08-18 Xin Zhang , Shixiang Shane Gu , Yutaka Matsuo , Yusuke Iwasawa

Widely adopted medical image segmentation methods, although efficient, are primarily deterministic and remain poorly amenable to natural language prompts. Thus, they lack the capability to estimate multiple proposals, human interaction, and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Yuan Lin , Murong Xu , Marc Hölle , Chinmay Prabhakar , Andreas Maier , Vasileios Belagiannis , Bjoern Menze , Suprosanna Shit

The Segment Anything Model (SAM) is a recently proposed prompt-based segmentation model in a generic zero-shot segmentation approach. With the zero-shot segmentation capacity, SAM achieved impressive flexibility and precision on various…

Computer Vision and Pattern Recognition · Computer Science 2023-08-30 Can Cui , Ruining Deng , Quan Liu , Tianyuan Yao , Shunxing Bao , Lucas W. Remedios , Yucheng Tang , Yuankai Huo

Deep learning has shown remarkable progress in medical image semantic segmentation, yet its success heavily depends on large-scale expert annotations and consistent data distributions. In practice, annotations are scarce, and images are…

Computer Vision and Pattern Recognition · Computer Science 2026-01-26 Ba-Thinh Lam , Thanh-Huy Nguyen , Hoang-Thien Nguyen , Quang-Khai Bui-Tran , Nguyen Lan Vi Vu , Phat K. Huynh , Ulas Bagci , Min Xu

The annotation scarcity of medical image segmentation poses challenges in collecting sufficient training data for deep learning models. Specifically, models trained on limited data may not generalize well to other unseen data domains,…

Image and Video Processing · Electrical Eng. & Systems 2023-07-19 Heng Li , Haojin Li , Wei Zhao , Huazhu Fu , Xiuyun Su , Yan Hu , Jiang Liu

Segment Anything Model (SAM) has emerged as a transformative approach in image segmentation, acclaimed for its robust zero-shot segmentation capabilities and flexible prompting system. Nonetheless, its performance is challenged by images…

Computer Vision and Pattern Recognition · Computer Science 2024-06-17 Wei-Ting Chen , Yu-Jiet Vong , Sy-Yen Kuo , Sizhuo Ma , Jian Wang

Segmentation is a crucial analysis task in biomedical imaging. Given the diverse experimental settings in this field, the lack of generalization limits the use of deep learning in practice. Domain adaptation is a promising remedy: it…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Anwai Archit , Constantin Pape

The Segment Anything Model (SAM) has revolutionized interactive segmentation through spatial prompting. While existing work primarily focuses on automating prompts in various settings, real-world annotation workflows involve iterative…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Prithwijit Chowdhury , Mohit Prabhushankar , Ghassan AlRegib

Leveraging the extensive training data from SA-1B, the Segment Anything Model (SAM) demonstrates remarkable generalization and zero-shot capabilities. However, as a category-agnostic instance segmentation method, SAM heavily relies on prior…

Computer Vision and Pattern Recognition · Computer Science 2023-11-30 Keyan Chen , Chenyang Liu , Hao Chen , Haotian Zhang , Wenyuan Li , Zhengxia Zou , Zhenwei Shi

Curating annotations for medical image segmentation is a labor-intensive and time-consuming task that requires domain expertise, resulting in "narrowly" focused deep learning (DL) models with limited translational utility. Recently,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-25 Pranav Kulkarni , Adway Kanhere , Dharmam Savani , Andrew Chan , Devina Chatterjee , Paul H. Yi , Vishwa S. Parekh

The Segment Anything Model (SAM), a foundational model designed for promptable segmentation tasks, demonstrates exceptional generalization capabilities, making it highly promising for natural scene image segmentation. However, SAM's lack of…

Computer Vision and Pattern Recognition · Computer Science 2024-08-19 Linghao Zheng , Xinyang Pu , Feng Xu

This work introduces a new framework, ProtoSAM, for one-shot medical image segmentation. It combines the use of prototypical networks, known for few-shot segmentation, with SAM - a natural image foundation model. The method proposed creates…

Computer Vision and Pattern Recognition · Computer Science 2024-07-19 Lev Ayzenberg , Raja Giryes , Hayit Greenspan

Open-vocabulary semantic segmentation aims to segment images into distinct semantic regions for both seen and unseen categories at the pixel level. Current methods utilize text embeddings from pre-trained vision-language models like CLIP…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Ziyu Zhao , Xiaoguang Li , Linjia Shi , Nasrin Imanpour , Song Wang

The Segment Anything Model (SAM) exhibits remarkable versatility and zero-shot learning abilities, owing largely to its extensive training data (SA-1B). Recognizing SAM's dependency on manual guidance given its category-agnostic nature, we…

Computer Vision and Pattern Recognition · Computer Science 2023-11-23 Xiyu Qi , Yifan Wu , Yongqiang Mao , Wenhui Zhang , Yidan Zhang

Medical image segmentation plays a pivotal role in clinical diagnostics and treatment planning, yet existing models often face challenges in generalization and in handling both 2D and 3D data uniformly. In this paper, we introduce Medical…

Computer Vision and Pattern Recognition · Computer Science 2024-12-06 Jiayuan Zhu , Abdullah Hamdi , Yunli Qi , Yueming Jin , Junde Wu

Segment Anything Model (SAM) has recently gained much attention for its outstanding generalization to unseen data and tasks. Despite its promising prospect, the vulnerabilities of SAM, especially to universal adversarial perturbation (UAP)…

Artificial Intelligence · Computer Science 2024-09-27 Ziqi Zhou , Yufei Song , Minghui Li , Shengshan Hu , Xianlong Wang , Leo Yu Zhang , Dezhong Yao , Hai Jin

Given a single labeled example, in-context segmentation aims to segment corresponding objects. This setting, known as one-shot segmentation in few-shot learning, explores the segmentation model's generalization ability and has been applied…

Computer Vision and Pattern Recognition · Computer Science 2025-04-18 Mengshi Qi , Pengfei Zhu , Xiangtai Li , Xiaoyang Bi , Lu Qi , Huadong Ma , Ming-Hsuan Yang

Despite their success, Segment Anything Models (SAMs) experience significant performance drops on severely degraded, low-quality images, limiting their effectiveness in real-world scenarios. To address this, we propose GleSAM, which…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Guangqian Guo , Yong Guo , Xuehui Yu , Wenbo Li , Yaoxing Wang , Shan Gao

Accurate vessel segmentation is critical for clinical applications such as disease diagnosis and surgical planning, yet remains challenging due to thin, branching structures and low texture contrast. While foundation models like the Segment…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Suzhong Fu , Rui Sun , Xuan Ding , Jingqi Dong , Yiming Yang , Yao Zhu , Min Chang Jordan Ren , Delin Deng , Angelica Aviles-Rivero , Shuguang Cui , Zhen Li