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Medical image registration is one of the key processing steps for biomedical image analysis such as cancer diagnosis. Recently, deep learning based supervised and unsupervised image registration methods have been extensively studied due to…

Computer Vision and Pattern Recognition · Computer Science 2019-07-03 Boah Kim , Jieun Kim , June-Goo Lee , Dong Hwan Kim , Seong Ho Park , Jong Chul Ye

The performance of a computer-aided automated diagnosis system of lung cancer from Computed Tomography (CT) volumetric images greatly depends on the accurate detection and segmentation of tumor regions. In this paper, we present Recurrent…

Image and Video Processing · Electrical Eng. & Systems 2020-09-09 Uday Kamal , Abdul Muntakim Rafi , Rakibul Hoque , Jonathan Wu , Md. Kamrul Hasan

Purpose: In some proton therapy facilities, patient alignment relies on two 2D orthogonal kV images, taken at fixed, oblique angles, as no 3D on-the-bed imaging is available. The visibility of the tumor in kV images is limited since the…

Computer Vision and Pattern Recognition · Computer Science 2023-10-19 Yuzhen Ding , Hongying Feng , Yunze Yang , Jason Holmes , Zhengliang Liu , David Liu , William W. Wong , Nathan Y. Yu , Terence T. Sio , Steven E. Schild , Baoxin Li , Wei Liu

Registration of pre-operative and post-recurrence brain images is often needed to evaluate the effectiveness of brain gliomas treatment. While recent deep learning-based deformable registration methods have achieved remarkable success with…

Image and Video Processing · Electrical Eng. & Systems 2022-06-09 Tony C. W. Mok , Albert C. S. Chung

Proton therapy offers superior organ-at-risk sparing but is highly sensitive to anatomical changes, making accurate deformable image registration (DIR) across longitudinal CT scans essential. Conventional DIR methods are often too slow for…

This study investigates the use of the unsupervised deep learning framework VoxelMorph for deformable registration of longitudinal abdominopelvic CT images acquired in patients with bone metastases from breast cancer. The CT images were…

Assessing cancer progression in liver CT scans is a clinical challenge, requiring a comparison of scans at different times for the same patient. Practitioners must identify existing tumors, compare them with prior exams, identify new…

Image and Video Processing · Electrical Eng. & Systems 2025-01-27 Walid Yassine , Martin Charachon , Céline Hudelot , Roberto Ardon

In adaptive radiotherapy, deformable image registration is often conducted between the planning CT and treatment CT (or cone beam CT) to generate a deformation vector field (DVF) for dose accumulation and contour propagation. The auto…

Medical Physics · Physics 2015-06-12 Xuejun Gu , Bin Dong , Jing Wang , John Yordy , Loren Mell , Xun Jia , Steve B. Jiang

Deformable medical image registration is an essential task in computer-assisted interventions. This problem is particularly relevant to oncological treatments, where precise image alignment is necessary for tracking tumor growth, assessing…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Stefano Fogarollo , Gregor Laimer , Reto Bale , Matthias Harders

Purpose: Radiotherapy presents unique challenges and clinical requirements for longitudinal tumor and organ-at-risk (OAR) prediction during treatment. The challenges include tumor inflammation/edema and radiation-induced changes in organ…

Computer Vision and Pattern Recognition · Computer Science 2021-09-01 Donghoon Lee , Sadegh R Alam , Jue Jiang , Pengpeng Zhang , Saad Nadeem , Yu-Chi Hu

During the radiotherapy treatment of patients with lung cancer, the radiation delivered to healthy tissue around the tumor needs to be minimized, which is difficult because of respiratory motion and the latency of linear accelerator…

Image and Video Processing · Electrical Eng. & Systems 2022-07-14 Michel Pohl , Mitsuru Uesaka , Kazuyuki Demachi , Ritu Bhusal Chhatkuli

Background and Purpose: Voxel-based analysis (VBA) helps to identify dose-sensitive regions by aligning individual dose distributions within a common coordinate system (CCS). Accurate deformable image registration (DIR) is essential for…

Medical Physics · Physics 2025-09-26 Xingyue Ruan , Xia Li , Muheng Li , Barbara Bachtiary , Antony Lomax , Zhiling Chen , Ye Zhang

Purpose: Deformable Image Registration (DIR) can benefit from additional guidance using corresponding landmarks in the images. However, the benefits thereof are largely understudied, especially due to the lack of automatic landmark…

Computer Vision and Pattern Recognition · Computer Science 2023-02-28 Monika Grewal , Jan Wiersma , Henrike Westerveld , Peter A. N. Bosman , Tanja Alderliesten

This paper aims to create a deep learning framework that can estimate the deformation vector field (DVF) for directly registering abdominal MRI-CT images. The proposed method assumed a diffeomorphic deformation. By using topology-preserved…

Computer Vision and Pattern Recognition · Computer Science 2024-05-07 Yang Lei , Luke A. Matkovic , Justin Roper , Tonghe Wang , Jun Zhou , Beth Ghavidel , Mark McDonald , Pretesh Patel , Xiaofeng Yang

Deep-learning-based registration methods emerged as a fast alternative to conventional registration methods. However, these methods often still cannot achieve the same performance as conventional registration methods because they are either…

Computer Vision and Pattern Recognition · Computer Science 2021-06-15 Alessa Hering , Stephanie Häger , Jan Moltz , Nikolas Lessmann , Stefan Heldmann , Bram van Ginneken

Background: Accurate deformable image registration (DIR) is required for contour propagation and dose accumulation in MR-guided adaptive radiotherapy (MRgART). This study trained and evaluated a deep learning DIR method for domain invariant…

Purpose: To determine whether deep learning models can distinguish between breast cancer molecular subtypes based on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). Materials and methods: In this institutional review…

Computer Vision and Pattern Recognition · Computer Science 2017-12-01 Zhe Zhu , Ehab Albadawy , Ashirbani Saha , Jun Zhang , Michael R. Harowicz , Maciej A. Mazurowski

Radiation therapy presents a need for dynamic tracking of a target tumor volume. Fiducial markers such as implanted gold seeds have been used to gate radiation delivery but the markers are invasive and gating significantly increases…

Computer Vision and Pattern Recognition · Computer Science 2019-09-27 Markus D. Foote , Blake E. Zimmerman , Amit Sawant , Sarang Joshi

Deformable image registration (DIR) is essential for many image-guided therapies. Recently, deep learning approaches have gained substantial popularity and success in DIR. Most deep learning approaches use the so-called mono-stream…

Image and Video Processing · Electrical Eng. & Systems 2020-12-08 Zhe Xu , Jie Luo , Jiangpeng Yan , Xiu Li , Jagadeesan Jayender

Recent studies show that deep learning (DL) based MRI reconstruction outperforms conventional methods, such as parallel imaging and compressed sensing (CS), in multiple applications. Unlike CS that is typically implemented with…

Image and Video Processing · Electrical Eng. & Systems 2022-08-22 Hongyi Gu , Burhaneddin Yaman , Steen Moeller , Il Yong Chun , Mehmet Akçakaya
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