English
Related papers

Related papers: Active learning for energy-based antibody optimiza…

200 papers

Deep learning has achieved widespread success in medical image analysis, leading to an increasing demand for large-scale expert-annotated medical image datasets. Yet, the high cost of annotating medical images severely hampers the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-14 Haoran Wang , Qiuye Jin , Shiman Li , Siyu Liu , Manning Wang , Zhijian Song

Foundational vision transformer models have shown impressive few shot performance on many vision tasks. This research presents a novel investigation into the application of parameter efficient fine-tuning methods within an active learning…

Computer Vision and Pattern Recognition · Computer Science 2024-06-17 Athmanarayanan Lakshmi Narayanan , Ranganath Krishnan , Amrutha Machireddy , Mahesh Subedar

Deep active inference has been proposed as a scalable approach to perception and action that deals with large policy and state spaces. However, current models are limited to fully observable domains. In this paper, we describe a deep active…

Machine Learning · Computer Science 2021-02-08 Otto van der Himst , Pablo Lanillos

Recent advances in image data processing through machine learning and especially deep neural networks (DNNs) allow for new optimization and performance-enhancement schemes for radiation detectors and imaging hardware through data-endowed…

Instrumentation and Detectors · Physics 2024-02-23 S. Lin , S. Ning , H. Zhu , T. Zhou , C. L. Morris , S. Clayton , M. Cherukara , R. T. Chen , Z. Wang

The design of molecules and materials with tailored properties is challenging, as candidate molecules must satisfy multiple competing requirements that are often difficult to measure or compute. While molecular structures, produced through…

Chemical Physics · Physics 2023-02-07 Julia Westermayr , Joe Gilkes , Rhyan Barrett , Reinhard J. Maurer

Pretraining with expert demonstrations have been found useful in speeding up the training process of deep reinforcement learning algorithms since less online simulation data is required. Some people use supervised learning to speed up the…

Artificial Intelligence · Computer Science 2018-02-12 Xiaoqin Zhang , Huimin Ma

Deep reinforcement learning has successfully been applied for molecular discovery as shown by the Molecule Deep Q-network (MolDQN) algorithm. This algorithm has challenges when applied to optimizing new molecules: training such a model is…

Machine Learning · Computer Science 2023-12-05 Huanyi Qin , Denis Akhiyarov , Sophie Loehle , Kenneth Chiu , Mauricio Araya-Polo

We present an algorithm for accelerating the search of molecule's adsorption site based on global optimization of surface adsorbate geometries. Our approach uses a machine-learning interatomic potential (moment tensor potential) to…

Materials Science · Physics 2024-12-30 Olga Klimanova , Nikita Rybin , Alexander Shapeev

Multimodal protein features play a crucial role in protein function prediction. However, these features encompass a wide range of information, ranging from structural data and sequence features to protein attributes and interaction…

Machine Learning · Computer Science 2025-11-07 Xiaoling Luo , Peng Chen , Chengliang Liu , Xiaopeng Jin , Jie Wen , Yumeng Liu , Junsong Wang

Machine Learning (ML)-based force fields are attracting ever-increasing interest due to their capacity to span spatiotemporal scales of classical interatomic potentials at quantum-level accuracy. They can be trained based on high-fidelity…

Chemical Physics · Physics 2024-06-03 Sebastien Röcken , Julija Zavadlav

Active learning seeks to reduce the amount of data required to fit the parameters of a model, thus forming an important class of techniques in modern machine learning. However, past work on active learning has largely overlooked latent…

Machine Learning · Computer Science 2024-02-20 Aditi Jha , Zoe C. Ashwood , Jonathan W. Pillow

We explore how Deep Learning (DL) can be utilized to predict prognosis of acute myeloid leukemia (AML). Out of TCGA (The Cancer Genome Atlas) database, 94 AML cases are used in this study. Input data include age, 10 common cytogenetic and…

Machine Learning · Computer Science 2018-11-01 Mei Lin , Vanya Jaitly , Iris Wang , Zhihong Hu , Lei Chen , Md. Amer Wahed , Zeyad Kanaan , Adan Rios , Andy N. D. Nguyen

Obtaining the exciton dynamics of large photosynthetic complexes by using mixed quantum mechanics/molecular mechanics (QM/MM) is computationally demanding. We propose a machine learning technique, multi-layer perceptrons, as a tool to…

Chemical Physics · Physics 2016-06-01 Florian Häse , Stéphanie Valleau , Edward Pyzer-Knapp , Alán Aspuru-Guzik

Enzyme mining is rapidly evolving as a data-driven strategy to identify biocatalysts with tailored functions from the vast landscape of uncharacterized proteins. The integration of machine learning into these workflows enables…

Biomolecules · Quantitative Biology 2025-07-11 Yanzi Zhang , Felix Moorhoff , Sizhe Qiu , Wenjuan Dong , David Medina-Ortiz , Jing Zhao , Mehdi D. Davari

The study of electromagnetic detection satellite scheduling problem (EDSSP) has attracted attention due to the detection requirements for a large number of targets. This paper proposes a mixed-integer programming model for the EDSSP problem…

Neural and Evolutionary Computing · Computer Science 2023-01-06 Yanjie Song , Luona Wei , Qing Yang , Jian Wu , Lining Xing , Yingwu Chen

For software that relies on machine-learned functionality, model selection is key to finding the right model for the task with desired performance characteristics. Evaluating a model requires developers to i) select from many models (e.g.…

Software Engineering · Computer Science 2024-01-30 Jai Kannan

Solar sensor-based monitoring systems have become a crucial agricultural innovation, advancing farm management and animal welfare through integrating sensor technology, Internet-of-Things, and edge and cloud computing. However, the…

Machine Learning · Computer Science 2025-05-07 Dian Chen , Zelin Wan , Dong Sam Ha , Jin-Hee Cho

Antibody-drug conjugate (ADC) has revolutionized the field of cancer treatment in the era of precision medicine due to their ability to precisely target cancer cells and release highly effective drug. Nevertheless, the realization of…

Machine Learning · Computer Science 2024-01-18 Liye Chen , Biaoshun Li , Yihao Chen , Mujie Lin , Shipeng Zhang , Chenxin Li , Yu Pang , Ling Wang

Morphological attributes from histopathological images and molecular profiles from genomic data are important information to drive diagnosis, prognosis, and therapy of cancers. By integrating these heterogeneous but complementary data, many…

Machine Learning · Computer Science 2022-02-28 Kaiwen Tan , Weixian Huang , Xiaofeng Liu , Jinlong Hu , Shoubin Dong

Recent advances in deep learning have resulted in great successes in various applications. Although semi-supervised or unsupervised learning methods have been widely investigated, the performance of deep neural networks highly depends on…

Computer Vision and Pattern Recognition · Computer Science 2020-04-07 Seong Tae Kim , Farrukh Mushtaq , Nassir Navab