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In photoacoustic tomography (PAT), a hybrid imaging modality that is based on the acoustic detection of optical absorption from biological tissue exposed to a pulsed laser, a short pulse laser generates an initial pressure proportional to…

Numerical Analysis · Mathematics 2026-03-27 Sunghwan Moon , Anwesa Dey , Souvik Roy

Photoacoustic tomography is an emerging medical imaging technology whose primary aim is to map the high-contrast optical properties of biological tissues by leveraging high-resolution ultrasound measurements. Mathematically, this can be…

Analysis of PDEs · Mathematics 2025-02-14 Alessandro Felisi

Photoacoustic tomography (PAT) is a hybrid imaging modality that intends to construct high-resolution images of optical properties of heterogeneous media from measured acoustic data generated by the photoacoustic effect. To date, most of…

Numerical Analysis · Mathematics 2019-08-07 Christina Frederick , Kui Ren , Sarah Vallélian

Compressed sensing (CS) is a promising approach to reduce the number of measurements in photoacoustic tomography (PAT) while preserving high spatial resolution. This allows to increase the measurement speed and to reduce system costs.…

We describe a technique to reveal speed-of-sound (SoS) variations within an echogenic sample. The technique uses the same receive data as standard pulse-echo imaging based on plane-wave compounding, and can be operated in parallel.…

Image and Video Processing · Electrical Eng. & Systems 2020-07-08 Nikunj Khetan , Timothy Weber , Jerome Mertz

The development of fast and accurate image reconstruction algorithms is a central aspect of computed tomography. In this paper, we investigate this issue for the sparse data problem in photoacoustic tomography (PAT). We develop a direct and…

Computer Vision and Pattern Recognition · Computer Science 2018-08-31 Stephan Antholzer , Markus Haltmeier , Johannes Schwab

Recent ultrasound imaging modalities based on ultrasound computed tomography indicate a huge potential to detect pathologies is tissue due to altered biomechanical properties. Especially the imaging of speed-of-sound (SoS) distribution in…

Medical Physics · Physics 2021-07-05 Richard Rau , Dieter Schweizer , Valery Vishnevskiy , Orcun Goksel

This paper presents a numerical study on a fast marching method based back projection reconstruction algorithm for photoacoustic tomography in heterogeneous media. Transcranial imaging is used here as a case study. To correct for the phase…

Medical Physics · Physics 2015-01-21 Tianren Wang , Yun Jing

The framework of ultrasound computed tomography (USCT) has recently re-emerged as a powerful, safe and operator-independent way to image the breast. State of the art image reconstruction methods are performed with iterative techniques based…

Medical Physics · Physics 2025-08-13 Luca A. Forte

Photoacoustic tomography (PAT) is an emerging imaging modality that aims at measuring the high-contrast optical properties of tissues by means of high-resolution ultrasonic measurements. The interaction between these two types of waves is…

Analysis of PDEs · Mathematics 2021-07-27 Giovanni S. Alberti , Paolo Campodonico , Matteo Santacesaria

Photoacoustic tomography (PAT) offers high optical contrast with acoustic imaging depth, making it essential for biomedical applications. While many all-optical systems have been developed to address limitations of ultrasound transducers,…

Optics · Physics 2024-10-11 Taeil Yoon , Hakseok Ko , Jeongmyo Im , Euiheon Chung , Wonshik Choi , Byeong Ha Lee

Noninvasive transcranial photoacoustic computed tomography (PACT) of the human brain, despite its clinical potential as a complementary technology to functional MRI, remains impeded by the acoustic distortion induced by the human skull. The…

Photoacoustic tomography (PAT) is a novel and rapidly promising technique in the field of medical imaging, based on the generation of acoustic waves inside an object of interest by stimulating non-ionizing laser pulses. This acoustic wave…

Analysis of PDEs · Mathematics 2022-02-08 Hyungyeong Jung , Sunghwan Moon

Speed-of-sound is a biomechanical property for quantitative tissue differentiation, with great potential as a new ultrasound-based image modality. A conventional ultrasound array transducer can be used together with an acoustic mirror, or…

Computer Vision and Pattern Recognition · Computer Science 2018-07-20 Valery Vishnevskiy , Sergio J Sanabria , Orcun Goksel

Significance: Dynamic photoacoustic computed tomography (PACT) is a valuable technique for monitoring physiological processes. However, current dynamic PACT techniques are often limited to 2D spatial imaging. While volumetric PACT imagers…

Signal Processing · Electrical Eng. & Systems 2023-10-03 Refik M. Cam , Chao Wang , Weylan Thompson , Sergey A. Ermilov , Mark A. Anastasio , Umberto Villa

Photoacoustic computed tomography (PACT) is a hybrid imaging modality, which combines the high optical contrast of pure optical imaging and the high penetration depth of ultrasound imaging. However, photoacoustic image dataset with good…

Medical Physics · Physics 2022-05-24 Tengbo Lyu , Changchun Yang , Jiadong Zhang , Shanshan Guo , Feng Gao , Fei Gao

Increasing the imaging speed is a central aim in photoacoustic tomography. This issue is especially important in the case of sequential scanning approaches as applied for most existing optical detection schemes. In this work we address this…

Numerical Analysis · Mathematics 2016-11-23 Markus Haltmeier , Thomas Berer , Sunghwan Moon , Peter Burgholzer

Optical coherence tomography (OCT) and photoacoustic tomography (PAT) are emerging non-invasive biological and medical imaging techniques. It is a recent trend in experimental science to design experiments that perform PAT and OCT imaging…

Analysis of PDEs · Mathematics 2016-04-19 Peter Elbau , Leonidas Mindrinos , Otmar Scherzer

Ultrasound computed tomography (USCT) quantifies acoustic tissue properties such as the speed-of-sound (SOS). Although full-waveform inversion (FWI) is an effective method for accurate SOS reconstruction, it can be computationally…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Gangwon Jeong , Fu Li , Trevor M. Mitcham , Umberto Villa , Nebojsa Duric , Mark A. Anastasio

In this paper, we propose a hybrid method to reconstruct the absorption coefficient by fluorescence photoacoustic tomography (FPAT), which combines a squeeze iterative method (SIM) and a nonlinear optimization method. The SIM is to use two…

Numerical Analysis · Mathematics 2019-01-30 Chao Wang , Tie Zhou