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Directed graphs are ubiquitous models for networks, and topological spaces they generate, such as the directed flag complex, have become useful objects in applied topology. The simplices are formed from directed cliques. We extend Atkin's…

Algebraic Topology · Mathematics 2022-02-16 Henri Riihimäki

It is nearly 20 years since the concept of a small-world network was first quantitatively defined, by a combination of high clustering and short path length; and about 10 years since this metric of complex network topology began to be…

Neurons and Cognition · Quantitative Biology 2016-08-22 Danielle S. Bassett , Edward T. Bullmore

-Background. Network neuroscience examines the brain as a complex system represented by a network (or connectome), providing deeper insights into the brain morphology and function, allowing the identification of atypical brain connectivity…

Neurons and Cognition · Quantitative Biology 2020-09-01 Mert Lostar , Islem Rekik

We propose high-order hypergraph walks as a framework to generalize graph-based network science techniques to hypergraphs. Edge incidence in hypergraphs is quantitative, yielding hypergraph walks with both length and width. Graph methods…

Physics and Society · Physics 2020-06-09 Sinan G. Aksoy , Cliff Joslyn , Carlos Ortiz Marrero , Brenda Praggastis , Emilie Purvine

We introduce new algebro-topological invariants of directed networks, based on the topological construction of the directed clique complex. The shape of the underlying directed graph is encoded in a way that can be studied mathematically to…

Neurons and Cognition · Quantitative Biology 2016-04-06 Paolo Masulli , Alessandro E. P. Villa

One important question in neuroscience is how global behavior in a brain network emerges from the interplay between network connectivity and the neural dynamics of individual nodes. To better understand this theoretical relationship, we…

Neurons and Cognition · Quantitative Biology 2022-09-13 Anca Radulescu , Johan Nakuci , Simone Evans , Sarah Muldoon

Network data has become widespread, larger, and more complex over the years. Traditional network data is dyadic, capturing the relations among pairs of entities. With the need to model interactions among more than two entities, significant…

Social and Information Networks · Computer Science 2025-05-30 Hao Tian , Reza Zafarani

Recent works on machine learning for combinatorial optimization have shown that learning based approaches can outperform heuristic methods in terms of speed and performance. In this paper, we consider the problem of finding an optimal…

Traditional functional connectivity based on functional magnetic resonance imaging (fMRI) can only capture pairwise interactions between brain regions. Hypergraphs, which reveal high-order relationships among multiple brain regions, have…

Neurons and Cognition · Quantitative Biology 2025-05-20 Wenqi Hu , Xuerui Su , Guanliang Li , Yidi Pan , Aijing Lin

Traditional Topological Data Analysis (TDA) methods, such as Persistent Homology (PH), rely on distance measures (e.g., cross-correlation, partial correlation, coherence, and partial coherence) that are symmetric by definition. While useful…

Neurons and Cognition · Quantitative Biology 2024-07-19 Anass B. El-Yaagoubi , Moo K. Chung , Hernando Ombao

Higher-order connectivity in complex systems described by simplexes of different orders provides a geometry for simplex-based dynamical variables and interactions. Simplicial complexes that constitute a functional geometry of the human…

Neurons and Cognition · Quantitative Biology 2020-06-19 Miroslav Andjelkovic , Bosiljka Tadic , Roderick Melnik

The Hopfield network model and its generalizations were introduced as a model of associative, or content-addressable, memory. They were widely investigated both as an unsupervised learning method in artificial intelligence and as a model of…

Neurons and Cognition · Quantitative Biology 2024-12-10 Marco Cafiso , Paolo Paradisi

The network representation is becoming increasingly popular for the description of cardiovascular interactions based on the analysis of multiple simultaneously collected variables. However, the traditional methods to assess network links…

We advance our approach of analyzing the dynamics of interacting complex systems with the nonlinear dynamics of interacting nonlinear elements. We replace the widely used lattice-like connection topology of cellular neural networks (CNN) by…

Neurons and Cognition · Quantitative Biology 2016-10-10 Henning Dickten , Christian E. Elger , Klaus Lehnertz

Resting-state functional MRI (rs-fMRI) in functional neuroimaging techniques have improved in brain disorders, dysfunction studies via mapping the topology of the brain connections, i.e. connectopic mapping. Since, there are the slight…

Image and Video Processing · Electrical Eng. & Systems 2019-07-18 Jalal Mirakhorli , Hamidreza Amindavar , Mojgan Mirakhorli

Hypergraphs and simplical complexes both capture the higher-order interactions of complex systems, ranging from higher-order collaboration networks to brain networks. One open problem in the field is what should drive the choice of the…

Physics and Society · Physics 2022-09-28 Federica Baccini , Filippo Geraci , Ginestra Bianconi

Graph Transformer shows remarkable potential in brain network analysis due to its ability to model graph structures and complex node relationships. Most existing methods typically model the brain as a flat network, ignoring its modular…

Machine Learning · Computer Science 2025-11-25 Jiajun Ma , Yongchao Zhang , Chao Zhang , Zhao Lv , Shengbing Pei

Brain network analysis plays an increasingly important role in studying brain function and the exploring of disease mechanisms. However, existing brain network construction tools have some limitations, including dependency on empirical…

Neurons and Cognition · Quantitative Biology 2024-07-29 Yongcheng Zong , Shuqiang Wang

Recently, graph theory has become a popular method for characterizing brain functional organization. One important goal in graph theoretical analysis of brain networks is to identify network differences across disease types or conditions.…

Applications · Statistics 2018-10-01 Ixavier A Higgins , Ying Guo , Suprateek Kundu , Ki Sueng Choi , Helen Mayberg

Higher-order networks encode the many-body interactions existing in complex systems, such as the brain, protein complexes, and social interactions. Simplicial complexes are higher-order networks that allow a comprehensive investigation of…

Social and Information Networks · Computer Science 2024-10-08 Xue Gong , Desmond J. Higham , Konstantinos Zygalakis , Ginestra Bianconi