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Accurate medical image segmentation is essential for effective diagnosis and treatment planning but is often challenged by domain shifts caused by variations in imaging devices, acquisition conditions, and patient-specific attributes.…

Image and Video Processing · Electrical Eng. & Systems 2024-12-06 Jie Bao , Zhixin Zhou , Wen Jung Li , Rui Luo

Current methods for developing foundation models in medical image segmentation rely on two primary assumptions: a fixed set of classes and the immediate availability of a substantial and diverse training dataset. However, this can be…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Xiaoyang Chen , Hao Zheng , Yifang Xie , Yuncong Ma , Tengfei Li

Deep convolutional neural networks have been proven to be very effective in image related analysis and tasks, such as image segmentation, image classification, image generation, etc. Recently many sophisticated CNN based architectures have…

Image and Video Processing · Electrical Eng. & Systems 2020-05-12 Eshal Zahra , Bostan Ali , Wajahat Siddique

Topological correctness plays a critical role in many image segmentation tasks, yet most networks are trained using pixel-wise loss functions, such as Dice, neglecting topological accuracy. Existing topology-aware methods often lack robust…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Laurin Lux , Alexander H. Berger , Alexander Weers , Nico Stucki , Daniel Rueckert , Ulrich Bauer , Johannes C. Paetzold

The combination of the U-Net based deep learning models and Transformer is a new trend for medical image segmentation. U-Net can extract the detailed local semantic and texture information and Transformer can learn the long-rang…

Image and Video Processing · Electrical Eng. & Systems 2023-04-05 Sheng He , Rina Bao , P. Ellen Grant , Yangming Ou

Since medical image data sets contain few samples and singular features, lesions are viewed as highly similar to other tissues. The traditional neural network has a limited ability to learn features. Even if a host of feature maps is…

Computer Vision and Pattern Recognition · Computer Science 2020-09-29 Hongfeng You , Long Yu , Shengwei Tian , Xiang Ma , Yan Xing , Xiaojie Ma

Image segmentation is to extract meaningful objects from a given image. For degraded images due to occlusions, obscurities or noises, the accuracy of the segmentation result can be severely affected. To alleviate this problem, prior…

Computer Vision and Pattern Recognition · Computer Science 2021-04-01 Daoping Zhang , Lok Ming Lui

The medical imaging literature has witnessed remarkable progress in high-performing segmentation models based on convolutional neural networks. Despite the new performance highs, the recent advanced segmentation models still require large,…

Image and Video Processing · Electrical Eng. & Systems 2020-02-13 Nima Tajbakhsh , Laura Jeyaseelan , Qian Li , Jeffrey Chiang , Zhihao Wu , Xiaowei Ding

Deep networks are now ubiquitous in large-scale multi-center imaging studies. However, the direct aggregation of images across sites is contraindicated for downstream statistical and deep learning-based image analysis due to inconsistent…

Image and Video Processing · Electrical Eng. & Systems 2021-04-16 Mengwei Ren , Neel Dey , James Fishbaugh , Guido Gerig

Accurate vessel segmentation is crucial to assist in clinical diagnosis by medical experts. However, the intricate tree-like tubular structure of blood vessels poses significant challenges for existing segmentation algorithms. Small…

Image and Video Processing · Electrical Eng. & Systems 2025-07-08 Xiao Zhang , Zhuo Jin , Shaoxuan Wu , Fengyu Wang , Guansheng Peng , Xiang Zhang , Ying Huang , JingKun Chen , Jun Feng

Semantic segmentation of medical images is pivotal in applications like disease diagnosis and treatment planning. While deep learning has excelled in automating this task, a major hurdle is the need for numerous annotated segmentation…

Image and Video Processing · Electrical Eng. & Systems 2024-09-02 Li Zhang , Basu Jindal , Ahmed Alaa , Robert Weinreb , David Wilson , Eran Segal , James Zou , Pengtao Xie

Models based on U-like structures have improved the performance of medical image segmentation. However, the single-layer decoder structure of U-Net is too "thin" to exploit enough information, resulting in large semantic differences between…

Image and Video Processing · Electrical Eng. & Systems 2023-09-08 Haoyuan Chen , Yufei Han , Pin Xu , Yanyi Li , Kuan Li , Jianping Yin

The advent of advanced crystallographic techniques has shifted structural biology from static, single-conformer models toward probing protein dynamics. Extracting cooperative motions from temporally and spatially averaged electron density…

Quantitative Methods · Quantitative Biology 2025-09-08 Avinash Mandaiya , Veit Elser

Using neural networks to solve variational problems, and other scientific machine learning tasks, has been limited by a lack of consistency and an inability to exactly integrate expressions involving neural network architectures. We address…

Machine Learning · Computer Science 2021-10-28 Jonas A. Actor , Andy Huang , Nathaniel Trask

Deep learning based models, generally, require a large number of samples for appropriate training, a requirement that is difficult to satisfy in the medical field. This issue can usually be avoided with a proper initialization of the…

Computer Vision and Pattern Recognition · Computer Science 2019-06-19 Taibou Birgui Sekou , Moncef Hidane , Julien Olivier , Hubert Cardot

For the task of medical image segmentation, fully convolutional network (FCN) based architectures have been extensively used with various modifications. A rising trend in these architectures is to employ joint-learning of the target region…

Computer Vision and Pattern Recognition · Computer Science 2019-08-16 Balamurali Murugesan , Kaushik Sarveswaran , Sharath M Shankaranarayana , Keerthi Ram , Jayaraj Joseph , Mohanasankar Sivaprakasam

Precise boundary segmentation of volumetric images is a critical task for image-guided diagnosis and computer-assisted intervention, especially for boundary confusion in clinical practice. However, U-shape networks cannot effectively…

Computer Vision and Pattern Recognition · Computer Science 2023-12-14 Xin You , Ming Ding , Minghui Zhang , Hanxiao Zhang , Yi Yu , Jie Yang , Yun Gu

Whole-body PET/CT scan is an important tool for diagnosing various malignancies (e.g., malignant melanoma, lymphoma, or lung cancer), and accurate segmentation of tumors is a key part for subsequent treatment. In recent years, CNN-based…

Image and Video Processing · Electrical Eng. & Systems 2023-02-27 Hengzhi Xue , Qingqing Fang , Yudong Yao , Yueyang Teng

We propose a segmentation framework that uses deep neural networks and introduce two innovations. First, we describe a biophysics-based domain adaptation method. Second, we propose an automatic method to segment white and gray matter, and…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Amir Gholami , Shashank Subramanian , Varun Shenoy , Naveen Himthani , Xiangyu Yue , Sicheng Zhao , Peter Jin , George Biros , Kurt Keutzer

Point-based interactive image segmentation can ease the burden of mask annotation in applications such as semantic segmentation and image editing. However, fully extracting the target mask with limited user inputs remains challenging. We…

Computer Vision and Pattern Recognition · Computer Science 2023-12-25 Chaowei Fang , Ziyin Zhou , Junye Chen , Hanjing Su , Qingyao Wu , Guanbin Li
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