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Large Language models (LLMs) have achieved encouraging results in tabular data generation. However, existing approaches require fine-tuning, which is computationally expensive. This paper explores an alternative: prompting a fixed LLM with…

Objective. Clinical AI documentation systems require evaluation methodologies that are clinically valid, economically viable, and sensitive to iterative changes. Methods requiring expert review per scoring instance are too slow and…

Long text classification is challenging for Large Language Models (LLMs) due to token limits and high computational costs. This study explores whether a Retrieval Augmented Generation (RAG) approach using only the most relevant text…

Large language models (LLMs), including zero-shot and few-shot paradigms, have shown promising capabilities in clinical text generation. However, real-world applications face two key challenges: (1) patient data is highly unstructured,…

Thematic analysis provides valuable insights into participants' experiences through coding and theme development, but its resource-intensive nature limits its use in large healthcare studies. Large language models (LLMs) can analyze text at…

Despite numerous applications for fine-grained corpus analysis, researchers continue to rely on manual labeling, which does not scale, or statistical tools like topic modeling, which are difficult to control. We propose that LLMs have the…

Prompt engineering, as an efficient and effective way to leverage Large Language Models (LLM), has drawn a lot of attention from the research community. The existing research primarily emphasizes the importance of adapting prompts to…

Developing artificial intelligence (AI) for clinical research requires a comprehensive data foundation that supports model training and rigorous evaluation. Here, we introduce TrialPanorama, a large-scale structured resource that aggregates…

Large Language Models (LLMs) have shown strong performance on NLP classification tasks. However, they typically rely on aggregated labels-often via majority voting-which can obscure the human disagreement inherent in subjective annotations.…

The training data of large language models (LLMs) comprises a wide range of biomedical literature, reflecting data from many different patient populations. We investigate how it might be possible to recover information on correlation and…

Removing Personally Identifiable Information (PII) from clinical notes in Electronic Health Records (EHRs) is essential for research and AI development. While Large Language Models (LLMs) are powerful, their high computational costs and the…

While there are high-quality software frameworks for information retrieval experimentation, they do not explicitly support cross-language information retrieval (CLIR). To fill this gap, we have created Patapsco, a Python CLIR framework.…

In-context learning (ICL) enables Large Vision-Language Models (LVLMs) to adapt to new tasks without parameter updates, using a few demonstrations from a large support set. However, selecting informative demonstrations leads to high…

In-context learning (ICL) allows a language model to improve its problem-solving capability when provided with suitable information in context. Since the choice of in-context information can be determined based on the problem itself,…

Background Concept extraction, a subdomain of natural language processing (NLP) with a focus on extracting concepts of interest, has been adopted to computationally extract clinical information from text for a wide range of applications…

The emergence of in-context learning (ICL) enables large pre-trained language models (PLMs) to make predictions for unseen inputs without updating parameters. Despite its potential, ICL's effectiveness heavily relies on the quality,…

Backgrounds: Information extraction (IE) is critical in clinical natural language processing (NLP). While large language models (LLMs) excel on generative tasks, their performance on extractive tasks remains debated. Methods: We…

Understanding and extracting structured insights from unstructured documents remains a foundational challenge in industrial NLP. While Large Language Models (LLMs) enable zero-shot extraction, traditional pipelines often fail to handle…

In-context learning (ICL) has transformed the use of large language models (LLMs) for NLP tasks, enabling few-shot learning by conditioning on labeled examples without finetuning. Despite its effectiveness, ICL is prone to errors,…

Large Language Models (LLM) hold immense promise for real-world applications, but their generic knowledge often falls short of domain-specific needs. Fine-tuning, a common approach, can suffer from catastrophic forgetting and hinder…