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Related papers: Extrapolative ML Models for Copolymers

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Ecologists have long suspected that species are more likely to interact if their traits match in a particular way. For example, a pollination interaction may be more likely if the proportions of a bee's tongue fit a plant's flower shape.…

Populations and Evolution · Quantitative Biology 2019-11-05 Maximilian Pichler , Virginie Boreux , Alexandra-Maria Klein , Matthias Schleuning , Florian Hartig

Definitive evidence that globular clusters (GCs) host intermediate-mass black holes (IMBHs) is elusive. Machine learning (ML) models trained on GC simulations can in principle predict IMBH host candidates based on observable features. This…

Astrophysics of Galaxies · Physics 2023-10-31 Mario Pasquato , Piero Trevisan , Abbas Askar , Pablo Lemos , Gaia Carenini , Michela Mapelli , Yashar Hezaveh

Linear interpolation between initial neural network parameters and converged parameters after training with stochastic gradient descent (SGD) typically leads to a monotonic decrease in the training objective. This Monotonic Linear…

Machine Learning · Computer Science 2021-04-26 James Lucas , Juhan Bae , Michael R. Zhang , Stanislav Fort , Richard Zemel , Roger Grosse

Machine learning (ML) methods have become powerful tools for predicting material properties with near first-principles accuracy and vastly reduced computational cost. However, the performance of ML models critically depends on the quality,…

Materials Science · Physics 2025-11-20 Pol Benítez , Cibrán López , Edgardo Saucedo , Teruyasu Mizoguchi , Claudio Cazorla

Retrieval-enhanced language models (LMs), which condition their predictions on text retrieved from large external datastores, have recently shown significant perplexity improvements compared to standard LMs. One such approach, the $k$NN-LM,…

Computation and Language · Computer Science 2022-10-31 Andrew Drozdov , Shufan Wang , Razieh Rahimi , Andrew McCallum , Hamed Zamani , Mohit Iyyer

Meta-learning models, or models that learn to learn, have been a long-desired target for their ability to quickly solve new tasks. Traditional meta-learning methods can require expensive inner and outer loops, thus there is demand for…

Neural and Evolutionary Computing · Computer Science 2021-03-12 Kevin Frans , Olaf Witkowski

Data-driven techniques are increasingly used to replace electronic-structure calculations of matter. In this context, a relevant question is whether machine learning (ML) should be applied directly to predict the desired properties or be…

Embedding molecular symmetries into machine-learning models is key for efficient learning of chemico-physical scalar properties, but little evidence on how to extend the same strategy to tensorial quantities exists. Here we formulate a…

Materials Science · Physics 2022-04-27 Vu Ha Anh Nguyen , Alessandro Lunghi

Chemical language models (CLMs) have emerged as promising competitors to popular classical machine learning models for molecular property prediction (MPP) tasks. However, an increasing number of studies have reported inconsistent and…

Machine Learning · Computer Science 2026-03-17 Mohammad Mostafanejad , Paul Saxe , T. Daniel Crawford

The rise of Big Data has led to new demands for Machine Learning (ML) systems to learn complex models with millions to billions of parameters, that promise adequate capacity to digest massive datasets and offer powerful predictive analytics…

Machine Learning · Statistics 2016-01-01 Eric P. Xing , Qirong Ho , Pengtao Xie , Wei Dai

We investigate the predictability of large language model (LLM) capabilities: given records of past experiments using different model families, numbers of parameters, tasks, and numbers of in-context examples, can we accurately predict LLM…

Computation and Language · Computer Science 2023-11-01 Qinyuan Ye , Harvey Yiyun Fu , Xiang Ren , Robin Jia

When using recurrent neural networks (RNNs) it is common practice to apply trained models to sequences longer than those seen in training. This "extrapolating" usage deviates from the traditional statistical learning setup where guarantees…

Machine Learning · Computer Science 2022-03-25 Edo Cohen-Karlik , Avichai Ben David , Nadav Cohen , Amir Globerson

Machine learning (ML)-based solutions are rapidly changing the landscape of many fields, including structural engineering. Despite their promising performance, these approaches are usually only demonstrated as proof-of-concept in structural…

Machine Learning · Computer Science 2025-08-20 Mohsen Zaker Esteghamati , Brennan Bean , Henry V. Burton , M. Z. Naser

Understanding the relationship between antibody sequence, structure and function is essential for the design of antibody-based therapeutics and research tools. Recently, machine learning (ML) models mostly based on the application of large…

Quantitative Methods · Quantitative Biology 2025-10-29 Kevin Michalewicz , Mauricio Barahona , Barbara Bravi

Discovering materials with desirable properties in an efficient way remains a significant problem in materials science. Many studies have tackled this problem by using different sets of information available about the materials. Among them,…

Materials Science · Physics 2025-03-04 Onur Boyar , Indra Priyadarsini , Seiji Takeda , Lisa Hamada

Molecules have a number of distinct properties whose importance and application vary. Often, in reality, labels for some properties are hard to achieve despite their practical importance. A common solution to such data scarcity is to use…

Machine Learning · Computer Science 2024-10-02 Chanhui Lee , Dae-Woong Jeong , Sung Moon Ko , Sumin Lee , Hyunseung Kim , Soorin Yim , Sehui Han , Sungwoong Kim , Sungbin Lim

The calculation of reactive properties is a challenging task in chemical reaction discovery. Machine learning (ML) methods play an important role in accelerating electronic structure predictions of activation energies and reaction…

Chemical Physics · Physics 2025-05-02 Joe Gilkes , Mark Storr , Reinhard J. Maurer , Scott Habershon

Internet service providers (ISPs) need to connect with other ISPs to provide global connectivity services to their users. To ensure global connectivity, ISPs can either use transit service(s) or establish direct peering relationships…

Machine Learning · Computer Science 2025-09-12 Md Ibrahim Ibne Alam , Ankur Senapati , Anindo Mahmood , Murat Yuksel , Koushik Kar

Polymers, composed of repeating structural units called monomers, are fundamental materials in daily life and industry. Accurate property prediction for polymers is essential for their design, development, and application. However, existing…

Machine Learning · Computer Science 2025-07-29 Jiaxi Wang , Yaosen Min , Xun Zhu , Miao Li , Ji Wu

The capabilities of large language models (LLMs) have expanded beyond natural language processing to scientific prediction tasks, including molecular property prediction. However, their effectiveness in in-context learning remains…