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Related papers: Quantum-inspired Reinforcement Learning for Synthe…

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Reinforcement learning competitions have formed the basis for standard research benchmarks, galvanized advances in the state-of-the-art, and shaped the direction of the field. Despite this, a majority of challenges suffer from the same…

Combining learned policies in a prioritized, ordered manner is desirable because it allows for modular design and facilitates data reuse through knowledge transfer. In control theory, prioritized composition is realized by null-space…

Machine Learning · Computer Science 2022-09-21 Finn Rietz , Erik Schaffernicht , Todor Stoyanov , Johannes A. Stork

Predicting and enhancing inherent properties based on molecular structures is paramount to design tasks in medicine, materials science, and environmental management. Most of the current machine learning and deep learning approaches have…

Machine Learning · Computer Science 2024-04-08 Zachary R. Fox , Ayana Ghosh

Lane change is a crucial vehicle maneuver which needs coordination with surrounding vehicles. Automated lane changing functions built on rule-based models may perform well under pre-defined operating conditions, but they may be prone to…

Robotics · Computer Science 2018-04-24 Pin Wang , Ching-Yao Chan , Arnaud de La Fortelle

Manipulate and control of the complex quantum system with high precision are essential for achieving universal fault tolerant quantum computing. For a physical system with restricted control resources, it is a challenge to control the…

Quantum Physics · Physics 2021-01-20 Zheng An , Qi-Kai He , Hai-Jing Song , D. L. Zhou

Reinforcement learning has been widely used in many problems, including quantum control of qubits. However, such problems can, at the same time, be solved by traditional, non-machine-learning methods, such as stochastic gradient descent and…

Quantum Physics · Physics 2021-05-06 Xiao-Ming Zhang , Zezhu Wei , Raza Asad , Xu-Chen Yang , Xin Wang

In neural combinatorial optimization (CO), reinforcement learning (RL) can turn a deep neural net into a fast, powerful heuristic solver of NP-hard problems. This approach has a great potential in practical applications because it allows…

Machine Learning · Computer Science 2021-07-14 Yeong-Dae Kwon , Jinho Choo , Byoungjip Kim , Iljoo Yoon , Youngjune Gwon , Seungjai Min

The integration of artificial intelligence (AI) in early-stage drug discovery offers unprecedented opportunities for exploring chemical space and accelerating hit-to-lead optimization. However, docking optimization in generative approaches…

Quantitative Methods · Quantitative Biology 2025-10-03 Ekaterina Podplutova , Anastasia Vepreva , Olga A. Konovalova , Vladimir Vinogradov , Dmitrii O. Shkil , Andrei Dmitrenko

Ensuring reliability in modern software systems requires rigorous pre-production testing across highly heterogeneous and evolving environments. Because exhaustive evaluation is infeasible, practitioners must decide how to allocate limited…

Software Engineering · Computer Science 2025-10-08 Yu Zhu

With recent advancements in quantum computing technology, optimizing quantum circuits and ensuring reliable quantum state preparation have become increasingly vital. Traditional methods often demand extensive expertise and manual…

The present work provides a new approach to evolve ligand structures which represent possible drug to be docked to the active site of the target protein. The structure is represented as a tree where each non-empty node represents a…

Neural and Evolutionary Computing · Computer Science 2016-11-15 Avishek Ghosh , Arnab Ghosh , Arkabandhu Chowdhury , Jubin Hazra

Synthesizability in generative molecular design remains a pressing challenge. Existing methods to assess synthesizability span heuristics-based methods, retrosynthesis models, and synthesizability-constrained molecular generation. The…

Biomolecules · Quantitative Biology 2024-07-18 Jeff Guo , Philippe Schwaller

In some applications of reinforcement learning, a dataset of pre-collected experience is already available but it is also possible to acquire some additional online data to help improve the quality of the policy. However, it may be…

Machine Learning · Computer Science 2023-07-11 Ruiqi Zhang , Andrea Zanette

Cut order planning (COP) is a critical challenge in the textile industry, directly impacting fabric utilization and production costs. Conventional methods based on static heuristics and catalog-based estimations often struggle to adapt to…

Machine Learning · Computer Science 2025-08-26 Yulison Herry Chrisnanto , Julian Evan Chrisnanto

Quantum machine learning is among the most exciting potential applications of quantum computing. However, the vulnerability of quantum information to environmental noises and the consequent high cost for realizing fault tolerance has…

Alpha factor mining aims to discover investment signals from the historical financial market data, which can be used to predict asset returns and gain excess profits. Powerful deep learning methods for alpha factor mining lack…

Computational Finance · Quantitative Finance 2025-06-18 Junjie Zhao , Chengxi Zhang , Min Qin , Peng Yang

Mixed discrete-continuous optimization is central to engineering design, where discrete choices interact with continuous fields. These problems are difficult due to high-dimensional, complex search spaces. To tackle them, Quantum Annealing…

Computational Engineering, Finance, and Science · Computer Science 2026-03-19 Fabian Key , Lukas Freinberger , Mayu Muramatsu , Norbert Hosters

Quantum Computing aims to streamline machine learning, making it more effective with fewer trainable parameters. This reduction of parameters can speed up the learning process and reduce the use of computational resources. However, in the…

Quantum Physics · Physics 2024-05-22 Michael Kölle , Timo Witter , Tobias Rohe , Gerhard Stenzel , Philipp Altmann , Thomas Gabor

We propose a novel reinforcement learning-based approach for adaptive and iterative feature selection. Given a masked vector of input features, a reinforcement learning agent iteratively selects certain features to be unmasked, and uses…

Machine Learning · Computer Science 2020-05-26 Uri Shaham , Tom Zahavy , Cesar Caraballo , Shiwani Mahajan , Daisy Massey , Harlan Krumholz

In recent years, control methods based on different optimization techniques have shed light on the possibilities of processing information in many quantum systems. When exploring the transmission of quantum states, faster transmission times…

Quantum Physics · Physics 2026-01-13 Sofía Perón Santana , Ariel Fiuri , Martín Domínguez , Omar Osenda
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