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Medical imaging provides essential visual insights for diagnosis, and multimodal large language models (MLLMs) are increasingly utilized for its analysis due to their strong generalization capabilities; however, the underlying factors…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Zhenyang Cai , Junying Chen , Rongsheng Wang , Weihong Wang , Yonglin Deng , Dingjie Song , Yize Chen , Zixu Zhang , Benyou Wang

In the field of document understanding, significant advances have been made in the fine-tuning of Multimodal Large Language Models (MLLMs) with instruction-following data. Nevertheless, the potential of text-grounding capability within…

Computer Vision and Pattern Recognition · Computer Science 2023-12-18 Yonghui Wang , Wengang Zhou , Hao Feng , Keyi Zhou , Houqiang Li

Out-of-context (OOC) detection is a challenging task involving identifying images and texts that are irrelevant to the context in which they are presented. Large vision-language models (LVLMs) are effective at various tasks, including image…

Computer Vision and Pattern Recognition · Computer Science 2024-03-15 Fatma Shalabi , Hichem Felouat , Huy H. Nguyen , Isao Echizen

Deep learning methods face dual challenges of limited clinical samples and low inter-class differentiation among Diffuse Cystic Lung Diseases (DCLDs) in advancing Birt-Hogg-Dube syndrome (BHD) diagnosis via Computed Tomography (CT) imaging.…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Haoqing Li , Jun Shi , Xianmeng Chen , Qiwei Jia , Rui Wang , Wei Wei , Hong An , Xiaowen Hu

In the era of Large Language Models (LLMs), tremendous strides have been made in the field of multimodal understanding. However, existing advanced algorithms are limited to effectively utilizing the immense representation capabilities and…

Artificial Intelligence · Computer Science 2023-09-06 Hao Feng , Zijian Wang , Jingqun Tang , Jinghui Lu , Wengang Zhou , Houqiang Li , Can Huang

Accurate and interpretable multi-disease diagnosis remains a critical challenge in medical research, particularly when leveraging heterogeneous multimodal medical data. Current approaches often rely on single-modal data, limiting their…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Yuting Zhang , Kaishen Yuan , Hao Lu , Yutao Yue , Jintai Chen , Kaishun Wu

Recent advancements in Large Multimodal Models (LMMs) have attracted interest in their generalization capability with only a few samples in the prompt. This progress is particularly relevant to the medical domain, where the quality and…

Computation and Language · Computer Science 2024-05-06 Seonhee Cho , Choonghan Kim , Jiho Lee , Chetan Chilkunda , Sujin Choi , Joo Heung Yoon

Multimodal Large Language Models (MLLMs) have exhibited immense potential across numerous medical specialties; yet, dentistry remains underexplored, in part due to limited domain-specific data, scarce dental expert annotations, insufficient…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Jing Hao , Yuci Liang , Lizhuo Lin , Yuxuan Fan , Wenkai Zhou , Kaixin Guo , Zanting Ye , Yanpeng Sun , Xinyu Zhang , Yanqi Yang , Qiankun Li , Hao Tang , James Kit-Hon Tsoi , Linlin Shen , Kuo Feng Hung

Multimodal language models (MLMs) show promise for clinical decision support and diagnostic reasoning, raising the prospect of end-to-end automated medical image interpretation. However, clinicians are highly selective in adopting AI tools;…

Artificial Intelligence · Computer Science 2025-08-06 Mahtab Bigverdi , Wisdom Ikezogwo , Kevin Zhang , Hyewon Jeong , Mingyu Lu , Sungjae Cho , Linda Shapiro , Ranjay Krishna

Multimodal large language models (MLLMs) have recently achieved remarkable progress in radiology by integrating visual perception with natural language understanding. However, they often generate clinically unsupported descriptions, known…

Computation and Language · Computer Science 2025-10-20 Xi Zhang , Zaiqiao Meng , Jake Lever , Edmond S. L. Ho

Large Language Models (LLMs) demonstrate strong generalization and reasoning abilities, making them well-suited for complex decision-making tasks such as medical consultation (MC). However, existing LLM-based methods often fail to capture…

Computation and Language · Computer Science 2025-10-13 Zhihao Jia , Mingyi Jia , Junwen Duan , Jianxin Wang

Microwell microfluidics has been utilized for single-cell analysis to reveal heterogeneity in gene expression, signaling pathways, and phenotypic responses for identifying rare cell types, understanding disease progression, and developing…

Neurons and Cognition · Quantitative Biology 2025-10-17 Dinh-Nguyen Nguyen , Sadia Shakil , Raymond Kai-Yu Tong , Ngoc-Duy Dinh

Artificial Intelligence models have demonstrated significant success in diagnosing skin diseases, including cancer, showing the potential to assist clinicians in their analysis. However, the interpretability of model predictions must be…

Computer Vision and Pattern Recognition · Computer Science 2025-08-29 Max Torop , Masih Eskandar , Nicholas Kurtansky , Jinyang Liu , Jochen Weber , Octavia Camps , Veronica Rotemberg , Jennifer Dy , Kivanc Kose

The integration of Computer-Aided Diagnosis (CAD) with Large Language Models (LLMs) presents a promising frontier in clinical applications, notably in automating diagnostic processes akin to those performed by radiologists and providing…

Computer Vision and Pattern Recognition · Computer Science 2024-05-22 Zihao Zhao , Sheng Wang , Jinchen Gu , Yitao Zhu , Lanzhuju Mei , Zixu Zhuang , Zhiming Cui , Qian Wang , Dinggang Shen

Multimodal Large Language Models (MLLMs) have shown success in various general image processing tasks, yet their application in medical imaging is nascent, lacking tailored models. This study investigates the potential of MLLMs in improving…

Computer Vision and Pattern Recognition · Computer Science 2024-05-13 Ling Yang , Zhanyu Wang , Zhenghao Chen , Xinyu Liang , Luping Zhou

The conventional pretraining-and-finetuning paradigm, while effective for common diseases with ample data, faces challenges in diagnosing data-scarce occupational diseases like pneumoconiosis. Recently, large language models (LLMs) have…

Image and Video Processing · Electrical Eng. & Systems 2024-07-02 Meiyue Song , Zhihua Yu , Jiaxin Wang , Jiarui Wang , Yuting Lu , Baicun Li , Xiaoxu Wang , Qinghua Huang , Zhijun Li , Nikolaos I. Kanellakis , Jiangfeng Liu , Jing Wang , Binglu Wang , Juntao Yang

Target volume contouring for radiation therapy is considered significantly more challenging than the normal organ segmentation tasks as it necessitates the utilization of both image and text-based clinical information. Inspired by the…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Yujin Oh , Sangjoon Park , Hwa Kyung Byun , Yeona Cho , Ik Jae Lee , Jin Sung Kim , Jong Chul Ye

Large Language Models (LLMs) are increasingly applied to medical imaging tasks, including image interpretation and synthetic image generation. However, these models often produce hallucinations, which are confident but incorrect outputs…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Anindya Bijoy Das , Shahnewaz Karim Sakib , Shibbir Ahmed

Precise spatial modeling in the operating room (OR) is foundational to many clinical tasks, supporting intraoperative awareness, hazard avoidance, and surgical decision-making. While existing approaches leverage large-scale multimodal…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Peiqi He , Zhenhao Zhang , Yixiang Zhang , Xiongjun Zhao , Shaoliang Peng

Multimodal artificial intelligence (AI) systems have the potential to enhance clinical decision-making by interpreting various types of medical data. However, the effectiveness of these models across all medical fields is uncertain. Each…