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We introduce a novel data-driven framework for the design of targeted gene panels for estimating exome-wide biomarkers in cancer immunotherapy. Our first goal is to develop a generative model for the profile of mutation across the exome,…

Genomics · Quantitative Biology 2022-02-04 Jacob R. Bradley , Timothy I. Cannings

Medical image analysis using deep neural networks has been actively studied. Deep neural networks are trained by learning data. For accurate training of deep neural networks, the learning data should be sufficient, of good quality, and…

Image and Video Processing · Electrical Eng. & Systems 2021-01-05 Sunho Kim , Byungjai Kim , HyunWook Park

The development of medical science greatly depends on the increased utilization of machine learning algorithms. By incorporating machine learning, the medical imaging field can significantly improve in terms of the speed and accuracy of the…

Image and Video Processing · Electrical Eng. & Systems 2024-09-01 Angona Biswas , MD Abdullah Al Nasim , Md Shahin Ali , Ismail Hossain , Md Azim Ullah , Sajedul Talukder

For most if not all cancers, prognosis is of significant importance, and extensive modeling research has been conducted. With the genetic nature of cancer, in the past two decades, multiple types of molecular data (such as gene expressions…

Applications · Statistics 2020-06-09 Sanguo Zhang , Yu Fan , Tingyan Zhong , Shuangge Ma

Recent developments in spatial omics technologies have enabled the generation of high dimensional molecular data, such as transcriptomes, proteomes, and epigenomes, within their spatial tissue context, either through coprofiling on the same…

Quantitative Methods · Quantitative Biology 2026-01-21 Esra Busra Isik , Yusuf Hakan Usta , Haozhe Liu , Maryam Riazi , William Roach , Hongpeng Zhou , Magnus Rattray , Sokratia Georgaka

Computational imaging has been playing a vital role in the development of natural sciences. Advances in sensory, information, and computer technologies have further extended the scope of influence of imaging, making digital images an…

Image and Video Processing · Electrical Eng. & Systems 2022-02-25 Bin Dong

Histopathological images contain rich phenotypic information that can be used to monitor underlying mechanisms contributing to diseases progression and patient survival outcomes. Recently, deep learning has become the mainstream…

Image and Video Processing · Electrical Eng. & Systems 2020-10-28 Chetan L. Srinidhi , Ozan Ciga , Anne L. Martel

Modern bio-technologies have produced a vast amount of high-throughput data with the number of predictors far greater than the sample size. In order to identify more novel biomarkers and understand biological mechanisms, it is vital to…

Machine Learning · Statistics 2018-05-18 Kevin He , Jian Kang , Hyokyoung Grace Hong , Ji Zhu , Yanming Li , Huazhen Lin , Han Xu , Yi Li

Medical image segmentation is a critical component in clinical practice, facilitating accurate diagnosis, treatment planning, and disease monitoring. However, existing methods, often tailored to specific modalities or disease types, lack…

Image and Video Processing · Electrical Eng. & Systems 2024-04-02 Jun Ma , Yuting He , Feifei Li , Lin Han , Chenyu You , Bo Wang

Epidemiology characterizes the influence of causes to disease and health conditions of defined populations. Cohort studies are population-based studies involving usually large numbers of randomly selected individuals and comprising numerous…

Computer Vision and Pattern Recognition · Computer Science 2015-01-19 Bernhard Preim , Paul Klemm , Helwig Hauser , Katrin Hegenscheid , Steffen Oeltze , Klaus Toennies , Henry Völzke

Breast cancer is one of the factors that cause the increase of mortality of women. The most widely used method for diagnosing this geological disease i.e. breast cancer is the ultrasound scan. Several key features such as the smoothness and…

Artificial Intelligence · Computer Science 2021-08-10 Mohamed Mejri , Aymen Mejri , Oumayma Mejri , Chiraz Fekih

Quantum Computing and especially Quantum Machine Learning, in a short period of time, has gained a lot of interest through research groups around the world. This can be seen in the increasing number of proposed models for pattern…

Quantum Physics · Physics 2020-12-23 Héctor Iván García Hernández , Raymundo Torres Ruiz , Guo-Hua Sun

Medical imaging is a form of technology that has revolutionized the medical field in the past century. In addition to radiology imaging of tumor tissues, digital pathology imaging, which captures histological details in high spatial…

Applications · Statistics 2020-12-03 Cong Zhang , Guanghua Xiao , Chul Moon , Min Chen , Qiwei Li

Cancer research is increasingly driven by the integration of diverse data modalities, spanning from genomics and proteomics to imaging and clinical factors. However, extracting actionable insights from these vast and heterogeneous datasets…

Cancer is a complex disease driven by dynamic regulatory shifts that cannot be fully captured by individual molecular profiling. We employ a data-driven approach to construct a coarse-grained dynamic network model based on hallmark…

Quantitative Methods · Quantitative Biology 2025-02-28 Jiahe Wang , Yan Wu , Yuke Hou , Yang Li , Dachuan Xu , Changjing Zhuge , Yue Han

Real-time computer-aided diagnosis using artificial intelligence (AI), with images, can help oncologists diagnose cancer with high accuracy and in an early phase. We reviewed real-time AI-based analyzed images for decision-making in…

Image and Video Processing · Electrical Eng. & Systems 2025-03-17 Leila Bagheriye , Johan Kwisthout

Non-invasive brain imaging techniques allow understanding the behavior and macro changes in the brain to determine the progress of a disease. However, computational pathology provides a deeper understanding of brain disorders at cellular…

Image and Video Processing · Electrical Eng. & Systems 2023-01-18 Gabriel Jimenez , Daniel Racoceanu

Cancer prognosis is a critical task that involves predicting patient outcomes and survival rates. To enhance prediction accuracy, previous studies have integrated diverse data modalities, such as clinical notes, medical images, and genomic…

Machine Learning · Computer Science 2025-02-04 Jie Peng , Shuang Zhou , Longwei Yang , Yiran Song , Mohan Zhang , Kaixiong Zhou , Feng Xie , Mingquan Lin , Rui Zhang , Tianlong Chen

The field of medical imaging is an essential aspect of the medical sciences, involving various forms of radiation to capture images of the internal tissues and organs of the body. These images provide vital information for clinical…

Artificial Intelligence · Computer Science 2023-06-21 Shuvra Sarker , Angona Biswas , MD Abdullah Al Nasim , Md Shahin Ali , Sai Puppala , Sajedul Talukder

Recent advancements in model checking have demonstrated significant potential across diverse applications, particularly in signal and image analysis. Medical imaging stands out as a critical domain where model checking can be effectively…

Computer Vision and Pattern Recognition · Computer Science 2025-01-08 Elhoucine Elfatimi , Lahcen El fatimi