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Automated interpretation of electrocardiograms (ECG) has garnered significant attention with the advancements in machine learning methodologies. Despite the growing interest, most current studies focus solely on classification or regression…

Signal Processing · Electrical Eng. & Systems 2023-11-07 Jielin Qiu , Jiacheng Zhu , Shiqi Liu , William Han , Jingqi Zhang , Chaojing Duan , Michael Rosenberg , Emerson Liu , Douglas Weber , Ding Zhao

Electrocardiogram (ECG) interpretation requires specialized expertise, often involving synthesizing insights from ECG signals with complex clinical queries posed in natural language. The scarcity of labeled ECG data coupled with the diverse…

Machine Learning · Computer Science 2025-05-09 Jialu Tang , Tong Xia , Yuan Lu , Cecilia Mascolo , Aaqib Saeed

Electrocardiogram (ECG) synthesis is the area of research focused on generating realistic synthetic ECG signals for medical use without concerns over annotation costs or clinical data privacy restrictions. Traditional ECG generation models…

Computation and Language · Computer Science 2023-03-17 Hyunseung Chung , Jiho Kim , Joon-myoung Kwon , Ki-Hyun Jeon , Min Sung Lee , Edward Choi

The success of Multimodal Large Language Models (MLLMs) in the medical auxiliary field shows great potential, allowing patients to engage in conversations using physiological signal data. However, general MLLMs perform poorly in cardiac…

Signal Processing · Electrical Eng. & Systems 2025-04-17 Yubao Zhao , Jiaju Kang , Tian Zhang , Puyu Han , Tong Chen

Leveraging Large Language Models (LLMs) with Retrieval-Augmented Generation (RAG) for analyzing medical data, particularly Electrocardiogram (ECG), offers high accuracy and convenience. However, generating reliable, evidence-based results…

Machine Learning · Computer Science 2025-05-08 Jin Yu , JaeHo Park , TaeJun Park , Gyurin Kim , JiHyun Lee , Min Sung Lee , Joon-myoung Kwon , Jeong Min Son , Yong-Yeon Jo

Interest in generative Electrocardiogram-Language Models (ELMs) is growing, as they can produce textual responses conditioned on ECG signals and textual queries. Unlike traditional classifiers that output label probabilities, ELMs are more…

Computation and Language · Computer Science 2025-10-02 Xiaoyu Song , William Han , Tony Chen , Chaojing Duan , Michael A. Rosenberg , Emerson Liu , Ding Zhao

Electrocardiography (ECG) offers critical cardiovascular insights, such as identifying arrhythmias and myocardial ischemia, but enabling automated systems to answer complex clinical questions directly from ECG signals (ECG-QA) remains a…

Signal Processing · Electrical Eng. & Systems 2025-05-13 Hung Manh Pham , Jialu Tang , Aaqib Saeed , Dong Ma

Electrocardiogram (ECG) monitoring is one of the most powerful technique of cardiovascular disease (CVD) early identification, and the introduction of intelligent wearable ECG devices has enabled daily monitoring. However, due to the need…

Signal Processing · Electrical Eng. & Systems 2024-03-08 Hongxiang Gao , Xingyao Wang , Zhenghua Chen , Min Wu , Jianqing Li , Chengyu Liu

Electrocardiogram (ECG) is the primary non-invasive diagnostic tool for monitoring cardiac conditions and is crucial in assisting clinicians. Recent studies have concentrated on classifying cardiac conditions using ECG data but have…

Computation and Language · Computer Science 2025-07-09 Zhongwei Wan , Che Liu , Xin Wang , Chaofan Tao , Hui Shen , Jing Xiong , Rossella Arcucci , Huaxiu Yao , Mi Zhang

Electrocardiography (ECG) plays a central role in cardiovascular diagnostics, yet existing automated approaches often struggle to generalize across clinical tasks and offer limited support for open-ended reasoning. We present HeartLLM, a…

Artificial Intelligence · Computer Science 2026-01-27 Jinning Yang , Wenjie Sun , Wen Shi

The advent of multimodal large language models (MLLMs) has sparked interest in their application to electrocardiogram (ECG) analysis. However, existing ECG-focused MLLMs primarily focus on report generation tasks, often limited to single…

Computation and Language · Computer Science 2025-11-13 Haitao Li , Ziyu Li , Yiheng Mao , Ziyi Liu , Zhoujian Sun , Zhengxing Huang

Recent advancements in Large Language Models (LLMs) have drawn increasing attention since the learned embeddings pretrained on large-scale datasets have shown powerful ability in various downstream applications. However, whether the learned…

Computation and Language · Computer Science 2023-02-07 Jielin Qiu , William Han , Jiacheng Zhu , Mengdi Xu , Michael Rosenberg , Emerson Liu , Douglas Weber , Ding Zhao

Electronic health records (EHRs) are long, noisy, and often redundant, posing a major challenge for the clinicians who must navigate them. Large language models (LLMs) offer a promising solution for extracting and reasoning over this…

Computation and Language · Computer Science 2025-08-21 Skatje Myers , Dmitriy Dligach , Timothy A. Miller , Samantha Barr , Yanjun Gao , Matthew Churpek , Anoop Mayampurath , Majid Afshar

Electrocardiogram (ECG) is essential for the clinical diagnosis of arrhythmias and other heart diseases, but deep learning methods based on ECG often face limitations due to the need for high-quality annotations. Although previous ECG…

Machine Learning · Computer Science 2025-02-18 Jiarui Jin , Haoyu Wang , Hongyan Li , Jun Li , Jiahui Pan , Shenda Hong

Electrocardiogram (ECG) analysis is crucial for diagnosing heart disease, but most self-supervised learning methods treat ECG as a generic time series, overlooking physiologic semantics and rhythm-level structure. Existing contrastive…

Machine Learning · Computer Science 2026-02-27 Xin Wang , Burcu Ozek , Aruna Mohan , Amirhossein Ravari , Or Zilbershot , Fatemeh Afghah

Recent advances have increasingly applied large language models (LLMs) to electrocardiogram (ECG) interpretation, giving rise to Electrocardiogram-Language Models (ELMs). Conditioned on an ECG and a textual query, an ELM autoregressively…

Artificial Intelligence · Computer Science 2025-05-27 William Han , Chaojing Duan , Zhepeng Cen , Yihang Yao , Xiaoyu Song , Atharva Mhaskar , Dylan Leong , Michael A. Rosenberg , Emerson Liu , Ding Zhao

Electrocardiography (ECG) serves as an indispensable diagnostic tool in clinical practice, yet existing multimodal large language models (MLLMs) remain unreliable for ECG interpretation, often producing plausible but clinically incorrect…

Computation and Language · Computer Science 2026-05-26 Jiarui Jin , Haoyu Wang , Xingliang Wu , Xiaocheng Fang , Xiang Lan , Zihan Wang , Deyun Zhang , Bo Liu , Yingying Zhang , Xian Wu , Hongyan Li , Shenda Hong

Electrocardiogram is a useful diagnostic signal that can detect cardiac abnormalities by measuring the electrical activity generated by the heart. Due to its rapid, non-invasive, and richly informative characteristics, ECG has many emerging…

Machine Learning · Computer Science 2025-12-09 Hanhui Deng , Xinglin Li , Jie Luo , Di Wu

With the widespread application of electroencephalography (EEG) in neuroscience and clinical practice, efficiently retrieving and semantically interpreting large-scale, multi-source, heterogeneous EEG data has become a pressing challenge.…

Computation and Language · Computer Science 2025-10-14 Yi Wang , Haoran Luo , Lu Meng , Ziyu Jia , Xinliang Zhou , Qingsong Wen

Electrocardiogram (ECG) analysis plays a vital role in the early detection, monitoring, and management of various cardiovascular conditions. While existing models have achieved notable success in ECG interpretation, they fail to leverage…

Machine Learning · Computer Science 2026-03-05 Yuhao Xu , Xiaoda Wang , Jiaying Lu , Sirui Ding , Defu Cao , Huaxiu Yao , Yan Liu , Xiao Hu , Carl Yang
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