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Thanks to novel, powerful brain activity recording techniques, we can create data-driven models from thousands of recording channels and large portions of the cortex, which can improve our understanding of brain-states neuromodulation and…

We consider sedimented at a solid wall particles that are immersed in water containing small additives of photosensitive ionic surfactants. It is shown that illumination with an appropriate wavelength, a beam intensity profile, shape and…

The soft character of organic materials leads to strong coupling between molecular nuclear and electronic dynamics. This coupling opens the way to control charge transport in organic electronic devices by inducing molecular vibrational…

Active forces occurring within cells can drive crucial biological processes that involve spontaneous organization and shape change, such as cell division. Motivated by recent in vitro experiments of nematic droplets of cytoskeletal…

Soft Condensed Matter · Physics 2021-02-16 Fabian Jan Schwarzendahl , Pierre Ronceray , Kimberly L. Weirich , Kinjal Dasbiswas

DNA methylation is a primary layer of epigenetic modification that plays a pivotal role in the regulation of development, aging, and cancer. The concurrent activity of opposing enzymes that mediate DNA methylation and demethylation gives…

Biological Physics · Physics 2026-02-10 Fabrizio Olmeda , Misha Gupta , Onurcan Bektas , Steffen Rulands

Amoeboid motion is a dynamic mode of cell motility essential for processes such as the immune response and wound healing. This review examines recent developments in the mathematical and computational modeling of amoeboid crawling, focusing…

Biological Physics · Physics 2026-03-17 Sergio Alonso , Carsten Beta

While it is commonly observed that the shape dynamics of mammalian cells can undergo large random fluctuations, theoretical models aiming at capturing cell mechanics often focus on the deterministic part of the motion. In this paper, we…

Biological Physics · Physics 2021-04-07 Vikram Deshpande , Antonio DeSimone , Robert McMeeking , Pierre Recho

Notch signaling is an evolutionary conserved cell-cell communication pathway. Besides regulating cell-fate decisions at an individual cell level, Notch signaling coordinates the emergent spatiotemporal patterning in a tissue through…

Molecular Networks · Quantitative Biology 2020-05-13 Federico Bocci , Jose Nelson Onuchic , Mohit Kumar Jolly

We introduce the notion of cell division-induced activity and show that the cell division generates extensile forces and drives dynamical patterns in cell assemblies. Extending the hydrodynamic models of lyotropic active nematics we…

Soft Condensed Matter · Physics 2015-08-07 Amin Doostmohammadi , Sumesh P. Thampi , Thuan B. Saw , Chwee T. Lim , Benoit Ladoux , Julia M. Yeomans

The ability of cells to sense and respond to the mechanical properties of their environments is fundamental to a range of cellular behaviours, with substrate stiffness increasingly being found to be a key signalling factor. Although active…

Cell Behavior · Quantitative Biology 2019-09-04 Carina M. Dunlop

Cell crawling on flat substrates is based on intracellular flows of the actin cytoskeleton that are driven by both actin polymerization at the front and myosin contractility at the back. The new experimental tool of optogenetics makes it…

Subcellular Processes · Quantitative Biology 2023-07-04 Oliver M. Drozdowski , Falko Ziebert , Ulrich S. Schwarz

Many critical biological processes, like wound healing, require confluent cell monolayers/bulk tissues to transition from a jammed solid-like to a fluid-like state. Although numerical studies anticipate changes in the cell shape alone can…

Soft Condensed Matter · Physics 2024-01-25 Pragya Arora , Souvik Sadhukhan , Saroj Kumar Nandi , Dapeng Bi , A K Sood , Rajesh Ganapathy

We study here the curious particle dynamics resulting from electro-osmotic flow around a microchannel junction corner whose dielectric walls are weakly polarizable. The hydrodynamic velocity field is obtained via superposition of a linear…

Fluid Dynamics · Physics 2015-06-19 Matan Zehavi , Gilad Yossifon

Artificial soft matter systems have appeared as important tools to harness mechanical motion for microscale manipulation. Typically, this motion is driven either by the external fields or by mutual interaction between the colloids. In the…

Soft Condensed Matter · Physics 2024-11-20 Rahul Chand , Ashutosh Shukla , Sneha Boby , G V Pavan Kumar

For the first time the phenomenon of cellular structure coarsening are consistently analysed from the positions of kinetic, hydrodynamic and stochastodynamic theories of nonequilibrium statistical systems. Thereby micro-, meso- and…

Condensed Matter · Physics 2015-06-25 S. B. Goryachev

A connection is established between discrete stochastic model describing microscopic motion of fluctuating cells, and macroscopic equations describing dynamics of cellular density. Cells move towards chemical gradient (process called…

Biological Physics · Physics 2010-05-18 Pavel M. Lushnikov , Nan Chen , Mark Alber

Coherent electrons such as those in electron microscopes, exhibit wave phenomena and may be described by the paraxial wave equation. In analogy to light-waves, governed by the same equation, these electrons share many of the fundamental…

Optics · Physics 2014-07-17 Roy Shiloh , Yossi Lereah , Yigal Lilach , Ady Arie

Cytoplasmic streaming, the persistent flow of fluid inside a cell, induces intracellular transport, which plays a key role in fundamental biological processes. In meiosis II mouse oocytes (developing egg cells) awaiting fertilisation, the…

Biological Physics · Physics 2024-10-18 Weida Liao , Eric Lauga

Coordinated movements of epithelia tissue are linked with active matter processes. We here consider the influence of curvature on the spatiotemporal arrangements and the shapes of the cells. The cells are represented by a multiphase field…

Soft Condensed Matter · Physics 2023-04-18 Lea Happel , Dennis Wenzel , Axel Voigt

In processes such as embryo shaping, wound healing, and malignant cell invasion, epithelial cells transition between dispersed phases, where the cells move independently, and condensed phases, where they aggregate and deform to close gaps,…

Soft Condensed Matter · Physics 2024-09-25 Anshuman Pasupalak , Zeng Wu , Massimo Pica Ciamarra