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In current noisy intermediate-scale quantum (NISQ) devices, hybrid quantum neural networks (HQNNs) offer a promising solution, combining the strengths of classical machine learning with quantum computing capabilities. However, the…

Quantum Physics · Physics 2025-01-27 Tasnim Ahmed , Muhammad Kashif , Alberto Marchisio , Muhammad Shafique

One of the main challenges in drug discovery is to find molecules that bind specifically and strongly to their target protein while having minimal binding to other proteins. By predicting binding affinity, it is possible to identify the…

Quantum Physics · Physics 2023-01-19 L. Domingo , M. Djukic , C. Johnson , F. Borondo

The emergence of Big Data changed how we approach information systems engineering. Nowadays, when we can use remote sensing techniques for Big Data acquisition, the issues such data introduce are as important as ever. One of those concerns…

Quantum Physics · Physics 2025-12-16 Tomasz Rybotycki , Manish K. Gupta , Piotr Gawron

Progressive neurodegenerative diseases, including Alzheimer's disease (AD), multiple sclerosis (MS), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS), exhibit complex, nonlinear trajectories that challenge deterministic…

Other Quantitative Biology · Quantitative Biology 2025-08-12 John D. Mayfield

Quantum Machine Learning (QML) hasn't yet demonstrated extensively and clearly its advantages compared to the classical machine learning approach. So far, there are only specific cases where some quantum-inspired techniques have achieved…

Quantum Physics · Physics 2022-11-30 Javier Mancilla , Christophe Pere

Accurately predicting turbulent flows remains a central challenge in fluid dynamics due to their high dimensionality and intrinsic nonlinearity. Recent developments in quantum algorithms and machine learning offer new opportunities for…

Fluid Dynamics · Physics 2025-11-25 Han Li , Yutong Lou , Dunhui Xiao

We propose a privacy-aware hybrid framework for federated medical image classification that combines tensor-network representation learning, MPC-secured aggregation, and post-aggregation quantum refinement. The framework is motivated by two…

Model quantization can reduce the model size and computational latency, it has become an essential technique for the deployment of deep neural networks on resourceconstrained hardware (e.g., mobile phones and embedded devices). The existing…

Computer Vision and Pattern Recognition · Computer Science 2021-03-10 Qigong Sun , Yan Ren , Licheng Jiao , Xiufang Li , Fanhua Shang , Fang Liu

Accurate amine property prediction is essential for optimizing CO2 capture efficiency in post-combustion processes. Quantum machine learning (QML) can enhance predictive modeling by leveraging superposition, entanglement, and interference…

Quantum Physics · Physics 2025-06-24 Hyein Cho , Jeonghoon Kim , Hocheol Lim

Quantum machine learning (QML) is a promising paradigm for tackling computational problems that challenge classical AI. Yet, the inherent probabilistic behavior of quantum mechanics, device noise in NISQ hardware, and hybrid…

Quantum Physics · Physics 2025-11-05 Ferhat Ozgur Catak , Jungwon Seo , Umit Cali

Quantum computers possess the potential to process data using a remarkably reduced number of qubits compared to conventional bits, as per theoretical foundations. However, recent experiments have indicated that the practical feasibility of…

Quantum Physics · Physics 2023-08-01 Alexander Geng , Ali Moghiseh , Claudia Redenbach , Katja Schladitz

With increasing life expectancy, AD has become a major global health concern. While classical AI-based methods have been developed for early diagnosis and stage classification of AD, growing data volumes and limited computational resources…

Machine Learning · Computer Science 2026-02-03 Emine Akpinar , Murat Oduncuoglu

Integrating quantum mechanics into drug discovery marks a decisive shift from empirical trial-and-error toward quantitative precision. However, the prohibitive cost of ab initio molecular dynamics has historically forced a compromise…

Quantum machine learning is at the crossroads of two of the most exciting current areas of research; quantum computing and classical machine learning. It explores the interaction between quantum computing and machine learning, investigating…

Quantum Physics · Physics 2021-12-14 Anekait Kariya , Bikash K. Behera

Learning with large-scale datasets and information-critical applications, such as in High Energy Physics (HEP), demands highly complex, large-scale models that are both robust and accurate. To tackle this issue and cater to the learning…

Machine Learning · Computer Science 2026-04-20 Abhishek Sawaika , Durga Pritam Suggisetti , Udaya Parampalli , Rajkumar Buyya

Recovery rate prediction plays a pivotal role in bond investment strategies by enhancing risk assessment, optimizing portfolio allocation, improving pricing accuracy, and supporting effective credit risk management. However, accurate…

Computational Finance · Quantitative Finance 2026-01-27 Ying Chen , Paul Griffin , Paolo Recchia , Lei Zhou , Hongrui Zhang

The deployment of Quantized Neural Networks (QNNs) on resource-constrained edge devices, such as microcontrollers (MCUs), introduces fundamental challenges in balancing model performance, computational complexity, and memory constraints.…

Machine Learning · Computer Science 2026-01-08 Hamza A. Abushahla , Dara Varam , Ariel Justine N. Panopio , Mohamed I. AlHajri

This work investigates how shallow, NISQ-compatible quantum layers can improve temporal representation learning in real-world sequential data. We develop a QLSTM Seq2Seq autoencoder in which a depth-1 variational quantum circuit is embedded…

Computational Engineering, Finance, and Science · Computer Science 2026-02-13 Tien-Ching Hsieh , Yun-Cheng Tsai , Samuel Yen-Chi Chen

While classical convolutional neural networks (CNNs) have revolutionized image classification, the emergence of quantum computing presents new opportunities for enhancing neural network architectures. Quantum CNNs (QCNNs) leverage quantum…

Quantum Physics · Physics 2025-05-16 Peter Röseler , Oliver Schaudt , Helmut Berg , Christian Bauckhage , Matthias Koch

In the NISQ-era of quantum computing, we should not expect to see quantum devices that provide an exponential improvement in runtime for practical problems, due to the lack of error correction and small number of qubits available.…

Quantum Physics · Physics 2019-07-02 Samuel S. Mendelson , Robert W. Strand , Guy B. Oldaker , Jacob M. Farinholt
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