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Predicting the neural response to natural images in the visual cortex requires extracting relevant features from the images and relating those feature to the observed responses. In this work, we optimize the feature extraction in order to…

Computer Vision and Pattern Recognition · Computer Science 2024-10-10 Alex Mulrooney , Austin J. Brockmeier

Music retrieval and recommendation applications often rely on content features encoded as embeddings, which provide vector representations of items in a music dataset. Numerous complementary embeddings can be derived from processing items…

Information Retrieval · Computer Science 2023-08-15 Andres Ferraro , Jaehun Kim , Sergio Oramas , Andreas Ehmann , Fabien Gouyon

Multi-label image classification presents a challenging task in many domains, including computer vision and medical imaging. Recent advancements have introduced graph-based and transformer-based methods to improve performance and capture…

Computer Vision and Pattern Recognition · Computer Science 2024-04-15 Ahmad Sajedi , Samir Khaki , Yuri A. Lawryshyn , Konstantinos N. Plataniotis

Molecular representation learning plays a crucial role in advancing applications such as drug discovery and material design. Existing work leverages 2D and 3D modalities of molecular information for pre-training, aiming to capture…

Machine Learning · Computer Science 2025-10-09 Tengwei Song , Min Wu , Yuan Fang

Integrating image and text data through multi-modal learning has emerged as a new approach in medical imaging research, following its successful deployment in computer vision. While considerable efforts have been dedicated to establishing…

Computer Vision and Pattern Recognition · Computer Science 2024-09-09 Fereshteh Shakeri , Yunshi Huang , Julio Silva-Rodríguez , Houda Bahig , An Tang , Jose Dolz , Ismail Ben Ayed

Molecular property prediction integrates quantum chemistry, cheminformatics, and deep learning to connect molecular structure with physicochemical and biological behavior. This survey traces four complementary paradigms, including Quantum,…

Molecular representation learning is crucial for the problem of molecular property prediction, where graph neural networks (GNNs) serve as an effective solution due to their structure modeling capabilities. Since labeled data is often…

Machine Learning · Computer Science 2023-09-26 Cameron Diao , Kaixiong Zhou , Zirui Liu , Xiao Huang , Xia Hu

Image-based profiling techniques have become increasingly popular over the past decade for their applications in target identification, mechanism-of-action inference, and assay development. These techniques have generated large datasets of…

Biomolecules · Quantitative Biology 2023-06-28 Cuong Q. Nguyen , Dante Pertusi , Kim M. Branson

Exploring how genetic sequences shape phenotypes is a fundamental challenge in biology and a key step toward scalable, hypothesis-driven experimentation. The task is complicated by the large modality gap between sequences and phenotypes, as…

Machine Learning · Computer Science 2025-11-18 Jingquan Yan , Yuwei Miao , Lei Yu , Yuzhi Guo , Xue Xiao , Lin Xu , Junzhou Huang

Most recent few-shot learning approaches are based on meta-learning with episodic training. However, prior studies encounter two crucial problems: (1) \textit{the presence of inductive bias}, and (2) \textit{the occurrence of catastrophic…

Multimedia · Computer Science 2024-09-18 Bingzhi Chen , Haoming Zhou , Yishu Liu , Biqing Zeng , Jiahui Pan , Guangming Lu

The effectiveness of learning in massive open online courses (MOOCs) can be significantly enhanced by introducing personalized intervention schemes which rely on building predictive models of student learning behaviors such as some…

Machine Learning · Computer Science 2018-12-20 Mucong Ding , Kai Yang , Dit-Yan Yeung , Ting-Chuen Pong

The versatility of multimodal deep learning holds tremendous promise for advancing scientific research and practical applications. As this field continues to evolve, the collective power of cross-modal analysis promises to drive…

Machine Learning · Computer Science 2025-05-15 Yifei Wang , Yunrui Li , Lin Liu , Pengyu Hong , Hao Xu

Although artificial intelligence (AI) has made significant progress in understanding molecules in a wide range of fields, existing models generally acquire the single cognitive ability from the single molecular modality. Since the hierarchy…

Machine Learning · Computer Science 2022-09-14 Bing Su , Dazhao Du , Zhao Yang , Yujie Zhou , Jiangmeng Li , Anyi Rao , Hao Sun , Zhiwu Lu , Ji-Rong Wen

Zero-shot classification of image scenes which can recognize the image scenes that are not seen in the training stage holds great promise of lowering the dependence on large numbers of labeled samples. To address the zero-shot image scene…

Computer Vision and Pattern Recognition · Computer Science 2023-06-12 Chun Liu , Suqiang Ma , Zheng Li , Wei Yang , Zhigang Han

Contrastive learning has emerged as a powerful method in deep learning, excelling at learning effective representations through contrasting samples from different distributions. However, neural collapse, where embeddings converge into a…

Machine Learning · Computer Science 2024-10-08 Huanran Li , Manh Nguyen , Daniel Pimentel-Alarcón

Biological systems encode function not primarily in steady states, but in the structure of transient responses elicited by time-varying stimuli. Overshoots, biphasic dynamics, adaptation kinetics, fold-change detection, entrainment, and…

Quantitative Methods · Quantitative Biology 2026-01-05 Eduardo D. Sontag

Medical decision-making requires integrating diverse medical information, from imaging to clinical narratives. These medical modalities are often acquired in a many-to-many manner. However, current medical vision-language pretraining models…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Yuan Gao , Sangwook Kim , Jianzhong You , Chris McIntosh

Molecule inverse folding has been a long-standing challenge in chemistry and biology, with the potential to revolutionize drug discovery and material science. Despite specified models have been proposed for different small- or…

Artificial Intelligence · Computer Science 2024-05-30 Zhangyang Gao , Jue Wang , Cheng Tan , Lirong Wu , Yufei Huang , Siyuan Li , Zhirui Ye , Stan Z. Li

By removing irrelevant and redundant features, feature selection aims to find a good representation of the original features. With the prevalence of unlabeled data, unsupervised feature selection has been proven effective in alleviating the…

Machine Learning · Computer Science 2024-03-25 Ziyuan Lin , Deanna Needell

Predicting interactions between small molecules and proteins is a crucial ingredient of the drug discovery process. In particular, accurate predictive models are increasingly used to preselect potential lead compounds from large molecule…

Quantitative Methods · Quantitative Biology 2007-09-26 Laurent Jacob , Jean-Philippe Vert
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