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Quantification of lymphoid aggregates including tertiary lymphoid structures with germinal centers in histology images of cancer is a promising approach for developing prognostic and predictive tissue biomarkers. In this article, we provide…

Tissues and Organs · Quantitative Biology 2024-03-08 Karina Silina , Francesco Ciompi

Accurate grasping point prediction is a key challenge for autonomous tissue manipulation in minimally invasive surgery, particularly in complex and variable procedures such as colorectal interventions. Due to their complexity and prolonged…

Computer Vision and Pattern Recognition · Computer Science 2026-02-20 Dennis N. Schneider , Lars Wagner , Daniel Rueckert , Dirk Wilhelm

Purpose: To determine whether deep learning-based algorithms applied to breast MR images can aid in the prediction of occult invasive disease following the di- agnosis of ductal carcinoma in situ (DCIS) by core needle biopsy. Material and…

Computer Vision and Pattern Recognition · Computer Science 2017-11-30 Zhe Zhu , Michael Harowicz , Jun Zhang , Ashirbani Saha , Lars J. Grimm , E. Shelley Hwang , Maciej A. Mazurowski

Mammography images are widely used to detect non-palpable breast lesions or nodules, preventing cancer and providing the opportunity to plan interventions when necessary. The identification of some structures of interest is essential to…

Image and Video Processing · Electrical Eng. & Systems 2023-07-21 Cesar A. Sierra-Franco , Jan Hurtado , Victor de A. Thomaz , Leonardo C. da Cruz , Santiago V. Silva , Alberto B. Raposo

Coronary Artery Disease (CAD) results from plaque deposit in a coronary artery. Early diagnosis is imperative, so a non-invasive detection method is being developed to identify acoustic signals caused by partial occlusions in the artery.…

Signal Processing · Electrical Eng. & Systems 2024-04-25 Bansi Mandalia , Steve Greenwald , Simon Shaw , Gregory Slabaugh

Breast cancer, the second leading cause of cancer-related deaths globally, accounts for a quarter of all cancer cases [1]. To lower this death rate, it is crucial to detect tumors early, as early-stage detection significantly improves…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Samia Saeed , Khuram Naveed

Self-Supervised Learning (SSL) has emerged as a powerful paradigm to mitigate the reliance on large, annotated datasets, a common bottleneck in medical image analysis. However, standard SSL methods, which rely on simple geometric and color…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Joao Batista Florindo

Clustering and visualizing high-dimensional (HD) data are important tasks in a variety of fields. For example, in bioinformatics, they are crucial for analyses of single-cell data such as mass cytometry (CyTOF) data. Some of the most…

Quantitative Methods · Quantitative Biology 2021-07-19 Joshua M. Scurll

Accurate classification of breast ultrasound images into benign, malignant, and normal categories is a critical clinical task complicated by speckle noise, acoustic shadowing, and inter-class visual ambiguity. Existing deep learning methods…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Chinedu Emmanuel Mbonu , Blessing Nwamaka Iduh , Joseph Ikechukwu Odo , Doris Chinedu Asogwa

Purpose: In this work, we present a collaboration to create a validation dataset of pathologist annotations for algorithms that process whole slide images (WSIs). We focus on data collection and evaluation of algorithm performance in the…

Microscopic histology image analysis is a cornerstone in early detection of breast cancer. However these images are very large and manual analysis is error prone and very time consuming. Thus automating this process is in high demand. We…

Computer Vision and Pattern Recognition · Computer Science 2018-10-23 Ismaël Koné , Lahsen Boulmane

Cancer diagnosis, prognosis, and therapeutic response prediction are heavily influenced by the relationship between the histopathological structures and the function of the tissue. Recent approaches acknowledging the structure-function…

Convolutional Neural Networks (CNN) have had a huge success in many areas of computer vision and medical image analysis. However, there is still an immense potential for performance improvement in mammogram breast cancer detection…

Computer Vision and Pattern Recognition · Computer Science 2018-08-28 Yeman Brhane Hagos , Albert Gubern Merida , Jonas Teuwen

Breast cancer is one of the main causes of death worldwide. Histopathological cellularity assessment of residual tumors in post-surgical tissues is used to analyze a tumor's response to a therapy. Correct cellularity assessment increases…

Image and Video Processing · Electrical Eng. & Systems 2019-09-04 Alexander Rakhlin , Aleksei Tiulpin , Alexey A. Shvets , Alexandr A. Kalinin , Vladimir I. Iglovikov , Sergey Nikolenko

This paper explores the problem of breast tissue classification of microscopy images. Based on the predominant cancer type the goal is to classify images into four categories of normal, benign, in situ carcinoma, and invasive carcinoma.…

Computer Vision and Pattern Recognition · Computer Science 2018-06-29 Kamyar Nazeri , Azad Aminpour , Mehran Ebrahimi

With the increase in the use of deep learning for computer-aided diagnosis in medical images, the criticism of the black-box nature of the deep learning models is also on the rise. The medical community needs interpretable models for both…

Image and Video Processing · Electrical Eng. & Systems 2020-12-21 Mookund Sureka , Abhijeet Patil , Deepak Anand , Amit Sethi

Deep Learning methods, specifically convolutional neural networks (CNNs), have seen a lot of success in the domain of image-based data, where the data offers a clearly structured topology in the regular lattice of pixels. This…

Machine Learning · Statistics 2018-05-31 Thomas Teh , Chaiyawan Auepanwiriyakul , John Alexander Harston , A. Aldo Faisal

Breast cancer is one of the leading causes of death among women across the globe. It is difficult to treat if detected at advanced stages, however, early detection can significantly increase chances of survival and improves lives of…

Image and Video Processing · Electrical Eng. & Systems 2023-08-17 Unaiza Sajid , Rizwan Ahmed Khan , Shahid Munir Shah , Sheeraz Arif

Breast density is an important risk factor for breast cancer that also affects the specificity and sensitivity of screening mammography. Current federal legislation mandates reporting of breast density for all women undergoing breast…

Cerebral Microbleeds (CMBs) are chronic deposits of small blood products in the brain tissues, which have explicit relation to various cerebrovascular diseases depending on their anatomical location, including cognitive decline,…

Image and Video Processing · Electrical Eng. & Systems 2023-06-27 Jun-Ho Kim , Young Noh , Haejoon Lee , Seul Lee , Woo-Ram Kim , Koung Mi Kang , Eung Yeop Kim , Mohammed A. Al-masni , Dong-Hyun Kim