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Biological transport networks are highly optimized structures that ensure power-efficient distribution of fluids across various domains, including animal vasculature and plant venation. Theoretically, these networks can be described as…

Biological Physics · Physics 2025-08-01 Albert Alonso , Lars Erik J. Skjegstad , Julius B. Kirkegaard

Highly-optimized complex transport networks serve crucial functions in many man-made and natural systems such as power grids and plant or animal vasculature. Often, the relevant optimization functional is non-convex and characterized by…

Biological Physics · Physics 2016-09-23 Henrik Ronellenfitsch , Eleni Katifori

An important feature of many complex systems, both natural and artificial, is the structure and organization of their interaction networks with interesting properties. Here we present a theory of self-organization by evolutionary adaptation…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Venkat Venkatasubramanian , Santhoji Katare , Priyan R. Patkar , Fangping Mu

Leaf venation is a pervasive example of a complex biological network, endowing leaves with a transport system and mechanical resilience. Transport networks optimized for efficiency have been shown to be trees, i.e. loopless. However,…

Biological Physics · Physics 2015-05-13 Eleni Katifori , Gergely J. Szöllősi , Marcelo O. Magnasco

Transport networks are typically optimized, either by evolutionary pressures in biological systems or by human design in engineered structures. In the case of systems such as the animal vasculature, the transport of fluids is hindered by…

Biological Physics · Physics 2023-02-27 Sean Fancher , Eleni Katifori

Transport networks are crucial to the functioning of natural and technological systems. Nature features transport networks that are adaptive over a vast range of parameters, thus providing an impressive level of robustness in supply.…

Adaptation and Self-Organizing Systems · Physics 2017-11-28 Erik Andreas Martens , Konstantin Klemm

The relation between network structure and dynamics is determinant for the behavior of complex systems in numerous domains. An important long-standing problem concerns the properties of the networks that optimize the dynamics with respect…

Adaptation and Self-Organizing Systems · Physics 2017-12-07 Takashi Nishikawa , Jie Sun , Adilson E. Motter

The recent discovery of universal principles underlying many complex networks occurring across a wide range of length scales in the biological world has spurred physicists in trying to understand such features using techniques from…

Biological Physics · Physics 2015-05-13 Sitabhra Sinha

Transport networks are crucial to the functioning of natural systems and technological infrastructures. For flow networks in many scenarios, such as rivers or blood vessels, acyclic networks (i.e., trees) are optimal structures when…

Adaptation and Self-Organizing Systems · Physics 2019-12-05 Erik Andreas Martens , Konstantin Klemm

Transport networks are crucial for the functioning of natural and technological systems. We study a mathematical model of vascular network adaptation, where the network structure dynamically adjusts to changes in blood flow and pressure.…

Adaptation and Self-Organizing Systems · Physics 2023-06-01 Konstantin Klemm , Erik Andreas Martens

The structure of networks that provide optimal transport properties has been investigated in a variety of contexts. While many different formulations of this problem have been considered, it is recurrently found that optimal networks are…

Biological Physics · Physics 2015-05-13 Francis Corson

The dynamics of flow within a material transport network is dependent upon the dynamics of its power source. Responding to a change of these dynamics is critical for the fitness of living flow networks, e.g. the animal vasculature, which…

Fluid Dynamics · Physics 2021-09-29 Sean Fancher , Eleni Katifori

As nutrients travel through microcirculation and are absorbed, their availability continuously decreases. However, a uniform nutrient distribution is critical, as it prevents tissue death in poorly supplied areas. How, then, do vascular…

Tissues and Organs · Quantitative Biology 2024-11-18 Georgios Gounaris , Mija Jovchevska , Miguel Ruiz Garcia , Eleni Katifori

A plethora of computational models have been developed in recent decades to account for the morphogenesis of complex biological fluid networks, such as capillary beds. Contemporary adaptation models are based on optimization schemes where…

Tissues and Organs · Quantitative Biology 2021-11-16 Felix Kramer , Carl D. Modes

Modular structure is ubiquitous among complex networks. We note that most such systems are subject to multiple structural and functional constraints, e.g., minimizing the average path length and the total number of links, while maximizing…

Physics and Society · Physics 2007-11-05 Raj Kumar Pan , Sitabhra Sinha

We present an analysis of the topologies of a class of networks which are optimal in terms of the requirements of having as short a route as possible between any two nodes while yet keeping the congestion in the network as low as possible.…

Statistical Mechanics · Physics 2009-11-10 Vittoria Colizza , Jayanth R. Banavar , Amos Maritan , Andrea Rinaldo

Transportation and distribution networks are a class of spatial networks that have been of interest in recent years. These networks are often characterized by the presence of complex structures such as central loops paired with peripheral…

Physics and Society · Physics 2023-01-23 Sebastiano Bontorin , Giulia Cencetti , Riccardo Gallotti , Bruno Lepri , Manlio De Domenico

Complex distribution networks are pervasive in biology. Examples include nutrient transport in the slime mold \emph{Physarum polycephalum} as well as mammalian and plant venation. Adaptive rules are believed to guide development of these…

Adaptation and Self-Organizing Systems · Physics 2019-12-16 Henrik Ronellenfitsch , Eleni Katifori

We build an evolutionary scenario that explains how some crucial physiological constraints in the arterial network of mammals - i.e. hematocrit, vessels diameters and arterial pressure drops - could have been selected by evolution. We…

Biological Physics · Physics 2014-05-22 Baptiste Moreau , Benjamin Mauroy

Cardiovascular networks span the body by branching across many generations of vessels. The resulting structure delivers blood over long distances to supply all cells with oxygen via the relatively short-range process of diffusion at the…

Medical Physics · Physics 2016-06-15 David Hunt , Van M. Savage
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