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Making evidence based decisions requires data. However for real-world applications, the privacy of data is critical. Using synthetic data which reflects certain statistical properties of the original data preserves the privacy of the…

Machine Learning · Computer Science 2021-05-28 Varun Chandrasekaran , Darren Edge , Somesh Jha , Amit Sharma , Cheng Zhang , Shruti Tople

With the rapid development of computer software and hardware technologies, more and more healthcare data are becoming readily available from clinical institutions, patients, insurance companies and pharmaceutical industries, among others.…

Machine Learning · Computer Science 2020-08-24 Jie Xu , Benjamin S. Glicksberg , Chang Su , Peter Walker , Jiang Bian , Fei Wang

To make medical datasets accessible without sharing sensitive patient information, we introduce a novel end-to-end approach for generative de-identification of dynamic medical imaging data. Until now, generative methods have faced…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Hadrien Reynaud , Qingjie Meng , Mischa Dombrowski , Arijit Ghosh , Thomas Day , Alberto Gomez , Paul Leeson , Bernhard Kainz

Synthetic data offers a promising path to train models while preserving data privacy. Differentially private (DP) finetuning of large language models (LLMs) as data generator is effective, but is impractical when computation resources are…

Computation and Language · Computer Science 2025-07-18 Bowen Tan , Zheng Xu , Eric Xing , Zhiting Hu , Shanshan Wu

With the rapid advancement of artificial intelligence and deep learning, medical image analysis has become a critical tool in modern healthcare, significantly improving diagnostic accuracy and efficiency. However, AI-based methods also…

Computer Vision and Pattern Recognition · Computer Science 2024-12-06 Yanming Zhu , Xuefei Yin , Alan Wee-Chung Liew , Hui Tian

Electronic health records (EHR) often contain sensitive medical information about individual patients, posing significant limitations to sharing or releasing EHR data for downstream learning and inferential tasks. We use normalizing flows…

Machine Learning · Statistics 2023-02-14 Bingyue Su , Yu Wang , Daniele E. Schiavazzi , Fang Liu

With the advent of machine learning in applications of critical infrastructure such as healthcare and energy, privacy is a growing concern in the minds of stakeholders. It is pivotal to ensure that neither the model nor the data can be used…

Machine Learning · Computer Science 2021-12-01 Dominique Mercier , Adriano Lucieri , Mohsin Munir , Andreas Dengel , Sheraz Ahmed

Training generative models with differential privacy (DP) typically involves injecting noise into gradient updates or adapting the discriminator's training procedure. As a result, such approaches often struggle with hyper-parameter tuning…

Machine Learning · Computer Science 2024-10-29 Kristjan Greenewald , Yuancheng Yu , Hao Wang , Kai Xu

Privacy protection is an ethical issue with broad concern in Artificial Intelligence (AI). Federated learning is a new machine learning paradigm to learn a shared model across users or organisations without direct access to the data. It has…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-08-25 Guodong Long , Tao Shen , Yue Tan , Leah Gerrard , Allison Clarke , Jing Jiang

In recent years, the growth of data across various sectors, including healthcare, security, finance, and education, has created significant opportunities for analysis and informed decision-making. However, these datasets often contain…

Machine Learning · Statistics 2026-04-30 Utsab Saha , Tanvir Muntakim Tonoy , Hafiz Imtiaz

Collaborative clinical decision support is often constrained by governance and privacy rules that prevent pooling patient-level records across institutions. We present a hybrid privacy-preserving framework that combines Federated Learning…

Machine Learning · Computer Science 2026-02-18 Farzana Akter , Rakib Hossain , Deb Kanna Roy Toushi , Mahmood Menon Khan , Sultana Amin , Lisan Al Amin

Precision medicine is an emerging approach for disease treatment and prevention that delivers personalized care to individual patients by considering their genetic makeups, medical histories, environments, and lifestyles. Despite the rapid…

Machine Learning · Computer Science 2021-11-11 William Briguglio , Parisa Moghaddam , Waleed A. Yousef , Issa Traore , Mohammad Mamun

Removing patient-specific information from medical images is crucial to enable sharing and open science without compromising patient identities. However, many methods currently used for deidentification have negative effects on downstream…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Adrienne Kline , Abhijit Gaonkar , Daniel Pittman , Chris Kuehn , Nils Forkert

Acquiring large quantities of data and annotations is known to be effective for developing high-performing deep learning models, but is difficult and expensive to do in the healthcare context. Adding synthetic training data using generative…

Image and Video Processing · Electrical Eng. & Systems 2023-10-06 Menghan Yu , Sourabh Kulhare , Courosh Mehanian , Charles B Delahunt , Daniel E Shea , Zohreh Laverriere , Ishan Shah , Matthew P Horning

Privacy concerns have attracted increasing attention in data-driven products due to the tendency of machine learning models to memorize sensitive training data. Generating synthetic versions of such data with a formal privacy guarantee,…

Computation and Language · Computer Science 2023-07-19 Xiang Yue , Huseyin A. Inan , Xuechen Li , Girish Kumar , Julia McAnallen , Hoda Shajari , Huan Sun , David Levitan , Robert Sim

With the rapid surge in the prevalence of Large Language Models (LLMs), individuals are increasingly turning to conversational AI for initial insights across various domains, including health-related inquiries such as disease diagnosis.…

Cryptography and Security · Computer Science 2024-05-07 Aditya Malik , Nalini Ratha , Bharat Yalavarthi , Tilak Sharma , Arjun Kaushik , Charanjit Jutla

Machine learning practitioners frequently seek to leverage the most informative available data, without violating the data owner's privacy, when building predictive models. Differentially private data synthesis protects personal details…

Machine Learning · Computer Science 2020-11-12 Lucas Rosenblatt , Xiaoyan Liu , Samira Pouyanfar , Eduardo de Leon , Anuj Desai , Joshua Allen

The biomedical field is among the sectors most impacted by the increasing regulation of Artificial Intelligence (AI) and data protection legislation, given the sensitivity of patient information. However, the rise of synthetic data…

Machine Learning · Computer Science 2024-04-26 Eric Macias-Fassio , Aythami Morales , Cristina Pruenza , Julian Fierrez

Healthcare federated learning requires strong privacy guarantees while maintaining computational efficiency across resource-constrained medical institutions. This paper presents MedHE, a novel framework combining adaptive gradient…

Cryptography and Security · Computer Science 2025-11-13 Farjana Yesmin

Machine Learning models thrive on vast datasets, continuously adapting to provide accurate predictions and recommendations. However, in an era dominated by privacy concerns, Machine Unlearning emerges as a transformative approach, enabling…

Machine Learning · Computer Science 2025-12-10 Robert Dilworth