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Universal Machine Learning Interatomic Potentials (uMLIPs), pre-trained on massively diverse datasets encompassing inorganic materials and organic molecules across the entire periodic table, serve as foundational models for quantum-accurate…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-04-20 Yuanchang Zhou , Hongyu Wang , Yiming Du , Yan Wang , Mingzhen Li , Siyu Hu , Xiangyu Zhang , Weijian Liu , Chen Wang , Zhuoqiang Guo , Long Wang , Jingde Bu , Yutong Lu , Guangming Tan , Weile Jia

Machine learning plays an increasingly important role in computational chemistry and materials science, complementing computationally intensive ab initio and first-principles methods. Despite their utility, machine-learning models often…

Chemical Physics · Physics 2025-05-06 Makoto Takamoto , Viktor Zaverkin , Mathias Niepert

Machine Learning Interatomic Potentials (MLIPs) are becoming a central tool in simulation-based chemistry. However, like most deep learning models, MLIPs struggle to make accurate predictions on out-of-distribution data or when trained in a…

Machine Learning · Computer Science 2026-01-19 Dario Coscia , Pim de Haan , Max Welling

Machine learning interatomic potentials (MLIPs) are routinely used atomic simulations, but generating databases of atomic configurations used in fitting these models is a laborious process, requiring significant computational and human…

Materials Science · Physics 2022-07-26 Connor Allen , Albert P. Bartók

Machine learning interatomic potentials (MLIPs) enable large-scale atomistic simulations but remain challenged in describing mixed-valence materials where charge ordering strongly influences thermodynamic stability. Here we investigate the…

In contrast to their empirical counterparts, machine-learning interatomic potentials (MLIAPs) promise to deliver near-quantum accuracy over broad regions of configuration space. However, due to their generic functional forms and extreme…

Materials Science · Physics 2025-02-04 Aparna P. A. Subramanyam , Danny Perez

First-principles atomistic simulations are essential for understanding complex material phenomena but are fundamentally limited by their computational cost. While Machine Learning Interatomic Potentials (MLIPs) have drastically improved…

Universal machine-learned interatomic potentials (U-MLIPs) have demonstrated effectiveness across diverse atomistic systems but often require fine-tuning for task-specific accuracy. We investigate the fine-tuning of two MACE-based…

Computational Physics · Physics 2025-06-10 Xiaoqing Liu , Kehan Zeng , Yangshuai Wang , Teng Zhao

An adaptive physics-inspired model design strategy for machine-learning interatomic potentials (MLIPs) is proposed. This strategy relies on iterative reconfigurations of composite models from single-term models, followed by a unified…

Materials Science · Physics 2026-02-27 Weishi Wang , Mark K. Transtrum , Vincenzo Lordi , Vasily V. Bulatov , Amit Samanta

Machine learning (ML) enables the development of interatomic potentials that promise the accuracy of first principles methods while retaining the low cost and parallel efficiency of empirical potentials. While ML potentials traditionally…

Foundational machine learning interatomic potentials (MLIPs) are being developed at a rapid pace, promising closer and closer approximation to ab initio accuracy. This unlocks the possibility to simulate much larger length and time scales.…

Materials Science · Physics 2026-05-27 Luuk H. E. Kempen , Raffaele Cheula , Mie Andersen

Machine-Learning Interatomic Potentials (MLIPs) have surged in popularity due to their promise of expanding the spatiotemporal scales possible for simulating molecules with high fidelity. The accuracy of any MLIP is dependent on the data…

Soft Condensed Matter · Physics 2026-02-27 Natalie E. Hooven , Arthur Y. Lin , Charles H. Carroll , Rose K. Cersonsky

Machine-learning interatomic potentials (MLIPs) have greatly extended the reach of atomic-scale simulations, offering the accuracy of first-principles calculations at a fraction of the cost. Leveraging large quantum mechanical databases and…

Dopants can tune the performance of MoS2 in various applications, but use of molecular dynamics simulations for doped MoS2 materials discovery is limited by the lack of multi-dopant interatomic potentials. Universal machine learning…

Materials Science · Physics 2026-03-02 Abrar Faiyad , Ashlie Martini

High-entropy alloys (HEAs) and their two-dimensional counterparts (2D-HEAs) have recently attracted attention due to their tunable properties and catalytic potential, yet their chemical complexity makes direct density functional theory…

Materials Science · Physics 2026-03-25 Chun Zhou , Hannu-Pekka Komsa

Machine learning interatomic potentials (MLIPs) balance high accuracy and lower costs compared to density functional theory calculations, but their performance often depends on the size and diversity of training datasets. Large datasets…

Machine Learning · Computer Science 2025-11-14 Benjamin Yu , Vincenzo Lordi , Daniel Schwalbe-Koda

Though offering unprecedented pathways to molecular dynamics (MD) simulations of technologically-relevant materials and conditions, machine-learning interatomic potentials (MLIPs) are typically trained for ``simple'' materials and…

Materials Science · Physics 2025-07-09 Nikola Koutná , Shuyao Lin , Lars Hultman , Davide G. Sangiovanni , Paul H. Mayrhofer

Machine-learning interatomic potentials have revolutionized materials modeling at the atomic scale. Thanks to these, it is now indeed possible to perform simulations of \abinitio quality over very large time and length scales. More…

Materials Science · Physics 2024-07-23 Haochen Yu , Matteo Giantomassi , Giuliana Materzanini , Junjie Wang , Gian-Marco Rignanese

Training machine learning interatomic potentials (MLIPs) on total energies of molecular clusters using differential or transfer learning is becoming a popular route to extend the accuracy of correlated wave-function theory to condensed…

Chemical Physics · Physics 2025-09-23 Mikołaj J. Gawkowski , Mingjia Li , Benjamin X. Shi , Venkat Kapil

Training of general-purpose machine learning interatomic potentials (MLIPs) relies on large datasets with properties usually computed with density functional theory (DFT). A pre-requisite for accurate MLIPs is that the DFT data are well…

Chemical Physics · Physics 2025-10-23 Domantas Kuryla , Fabian Berger , Gábor Csányi , Angelos Michaelides