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We use Quantum Imaginary Time Evolution (QITE) to solve polynomial unconstrained binary optimization (PUBO) problems. We show that a linear Ansatz yields good results for a wide range of PUBO problems, often outperforming standard classical…

Quantum Physics · Physics 2023-12-29 Nora M. Bauer , Rizwanul Alam , James Ostrowski , George Siopsis

We introduce a novel quadratic unconstrained binary optimization (QUBO) formulation for a classical problem in electrical engineering -- the optimal reconfiguration of distribution grids. For a given graph representing the grid…

Quantum Physics · Physics 2023-01-31 Filipe F. C. Silva , Pedro M. S. Carvalho , Luis A. F. M. Ferreira , Yasser Omar

This study investigates quantum computing approaches for solving the windfarm layout optimization (WFLO) problems formulated as a quadratic unconstrained binary optimization (QUBO) problem. We investigate two encoding methods that require…

Quantum Physics · Physics 2025-12-22 James Hancock , Matthew Craven , Craig McNeile

We present a new method that efficiently solves TO problems and provides a practical pathway to leverage quantum computing to exploit potential quantum advantages. This work targets on large-scale, multi-material TO challenges for…

Computational Physics · Physics 2026-01-16 Zisheng Ye , Wenxiao Pan

Many computational problems involve optimization over discrete variables with quadratic interactions. Known as discrete quadratic models (DQMs), these problems in general are NP-hard. Accordingly, there is increasing interest in encoding…

Quantum Physics · Physics 2024-02-16 Tristan Zaborniak , Ulrike Stege

A quantum annealer heuristically minimizes quadratic unconstrained binary optimization (QUBO) problems, but is limited by the physical hardware in the size and density of the problems it can handle. We have developed a meta-heuristic solver…

Discrete Mathematics · Computer Science 2016-05-20 Gili Rosenberg , Mohammad Vazifeh , Brad Woods , Eldad Haber

Steric clashes pose a challenge when exploring dense protein systems using conventional explicit-chain methods. A minimal example is a single lattice protein confined on a minimal grid, with no free sites. Finding its minimum energy is a…

Quantum Physics · Physics 2025-10-03 Anders Irbäck , Lucas Knuthson , Sandipan Mohanty

In previous research, quantum resources were concretely estimated for solving Elliptic Curve Discrete Logarithm Problem(ECDLP). In [1], the quantum algorithm was optimized for the binary elliptic curves and the main optimization target was…

Quantum Physics · Physics 2023-03-14 Hyeonhak Kim , Seokhie Hong

Integer programming (IP) is an NP-hard combinatorial optimization problem that is widely used to represent a diverse set of real-world problems spanning multiple fields, such as finance, engineering, logistics, and operations research. It…

Quantum Physics · Physics 2025-08-20 Kapil Goswami , Peter Schmelcher , Rick Mukherjee

The quantum approximate optimization algorithm (QAOA) is a leading candidate algorithm for solving optimization problems on quantum computers. However, the potential of QAOA to tackle classically intractable problems remains unclear. Here,…

The Cable Routing Optimization Problem (CROP) is a Multi-Commodity Flow Problem (MCFP) central to industrial layouts and smart manufacturing. Historically, quantum optimization has modeled MCFPs as Quadratic Unconstrained Binary…

Quadratic Unconstrained Binary Optimization models are useful for solving a diverse range of optimization problems. Constraints can be added by incorporating quadratic penalty terms into the objective, often with the introduction of slack…

Optimization and Control · Mathematics 2021-05-18 Amit Verma , Mark Lewis

Quantum optimization algorithms hold the promise of solving classically hard, discrete optimization problems in practice. The requirement of encoding such problems in a Hamiltonian realized with a finite -- and currently small -- number of…

Quantum Physics · Physics 2023-07-10 Yifeng Rocky Zhu , David Joseph , Cong Ling , Florian Mintert

The vehicle routing problem with time windows (VRPTW) is a common optimization problem faced within the logistics industry. In this work, we explore the use of a previously-introduced qubit encoding scheme to reduce the number of binary…

Quantum Physics · Physics 2023-09-20 Ioannis D. Leonidas , Alexander Dukakis , Benjamin Tan , Dimitris G. Angelakis

We present a novel formulation of structural design optimization problems specifically tailored to be solved by quantum annealing (QA). Structural design optimization aims to find the best, i.e., material-efficient yet high-performance,…

Computational Engineering, Finance, and Science · Computer Science 2024-04-17 Fabian Key , Lukas Freinberger

Quantum annealing is a method developed to solve combinatorial optimization problems by utilizing quantum bits. Solving such problems corresponds to minimizing a cost function defined over binary variables. However, in many practical cases,…

Quantum Physics · Physics 2025-06-26 Seiya Endo , Shohei Kawakatsu , Hiromichi Matsuyama , Kohei Suzuki , Yuichiro Matsuzaki

Quantum computing is developing fast. Real world applications are within reach in the coming years. One of the most promising areas is combinatorial optimisation, where the Quadratic Unconstrained Binary Optimisation (QUBO) problem…

Quantum Physics · Physics 2020-07-06 Frank Phillipson , Irina Chiscop

We show how to carry out quantum logical operations (controlled-not and Toffoli gates) on encoded qubits for several encodings which protect against various 1-bit errors. This improves the reliability of these operations by allowing one to…

Quantum Physics · Physics 2009-10-30 Wojciech Hubert Zurek , Raymond Laflamme

This paper proposes QDFO, a dataflow-based optimization approach to Microsoft QIR. QDFO consists of two main functions: one is to preprocess the QIR code so that the LLVM optimizer can capture more optimization opportunities, and the other…

Programming Languages · Computer Science 2024-07-01 Junjie Luo , Haoyu Zhang , Jianjun Zhao

We present QUBO.jl, an end-to-end Julia package for working with QUBO (Quadratic Unconstrained Binary Optimization) instances. This tool aims to convert a broad range of JuMP problems for straightforward application in many physics and…

Optimization and Control · Mathematics 2023-09-04 Pedro Maciel Xavier , Pedro Ripper , Tiago Andrade , Joaquim Dias Garcia , Nelson Maculan , David E. Bernal Neira
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