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Accurate blood glucose prediction can enable novel interventions for type 1 diabetes treatment, including personalized insulin and dietary adjustments. Although recent advances in transformer-based architectures have demonstrated the power…

Quantitative Methods · Quantitative Biology 2025-05-15 Meryem Altin Karagoz , Marc D. Breton , Anas El Fathi

We consider the question of 30-minute prediction of blood glucose levels measured by continuous glucose monitoring devices, using clinical data. While most studies of this nature deal with one patient at a time, we take a certain percentage…

Machine Learning · Computer Science 2017-07-20 H. N. Mhaskar , S. V. Pereverzyev , M. D. van der Walt

Non-invasive glucose monitoring remains a critical challenge in the management of diabetes. HRV during sleep shows promise for glucose prediction however, age-related autonomic changes significantly confound traditional HRV analyses. We…

Signal Processing · Electrical Eng. & Systems 2025-08-20 Md Basit Azam , Sarangthem Ibotombi Singh

Modeling the dynamics of probability distributions from time-dependent data samples is a fundamental problem in many fields, including digital health. The goal is to analyze how the distribution of a biomarker, such as glucose, changes over…

Machine Learning · Statistics 2025-09-18 Antonio Álvarez-López , Marcos Matabuena

Motivated by the need to study the molecular mechanism underlying Type 1 Diabetes (T1D) with the gene expression data collected from both the patients and healthy controls at multiple time points, we propose an innovative method for jointly…

Methodology · Statistics 2018-12-10 Bochao Jia , Faming Liang , the TEDDY Study Group

Effective and accurate diagnosis of Diabetes Mellitus (DM), as well as its early stage Impaired Glucose Regulation (IGR), has attracted much attention recently. Traditional Chinese Medicine (TCM) [3], [5] etc. has proved that tongue, face…

Computer Vision and Pattern Recognition · Computer Science 2016-04-13 Jinxing Li , David Zhang , Yongcheng Li , Jian Wu

This work proposes a smartphone video-based approach for the estimation of blood glucose in a non-invasive way. Videos using smartphone camera are collected from the tip of the subjects finger and the frames are subsequently converted into…

Signal Processing · Electrical Eng. & Systems 2019-12-02 Tauseef Tasin Chowdhury , Tahmin Mishma , Md. Saeem Osman , Tanzilur Rahman

In the context of time-series forecasting, we propose a LSTM-based recurrent neural network architecture and loss function that enhance the stability of the predictions. In particular, the loss function penalizes the model, not only on the…

Signal Processing · Electrical Eng. & Systems 2020-09-09 Maxime De Bois , Mounîm A. El Yacoubi , Mehdi Ammi

Background and objective: Diabetes is one of the four leading causes of death worldwide, necessitating daily blood glucose monitoring. While sweat offers a promising non-invasive alternative for glucose monitoring, its application remains…

Quantitative Methods · Quantitative Biology 2024-12-05 Xiaoyu Yin , Elisabetta Peri , Eduard Pelssers , Jaap den Toonder , Lisa Klous , Hein Daanen , Massimo Mischi

Regular monitoring of glycemic status is essential for diabetes management, yet conventional blood-based testing can be burdensome for frequent assessment. The sclera contains superficial microvasculature that may exhibit diabetes related…

Image and Video Processing · Electrical Eng. & Systems 2026-03-16 Muhammad Ahmed Khan , Manqiang Peng , Ding Lin , Saif Ur Rehman Khan

Describing dynamic medical systems using machine learning is a challenging topic with a wide range of applications. In this work, the possibility of modeling the blood glucose level of diabetic patients purely on the basis of measured data…

Machine Learning · Computer Science 2023-03-10 David Jödicke , Daniel Parra , Gabriel Kronberger , Stephan Winkler

Cardiovascular disease and chronic kidney disease are major complications of diabetes, leading to high morbidity and mortality. Early detection of these conditions is critical, yet traditional diagnostic markers often lack sensitivity in…

Other Quantitative Biology · Quantitative Biology 2025-10-20 Syed Ibad Hasnain

Recent advances in SSL enabled novel medical AI models, known as foundation models, offer great potential for better characterizing health from diverse biomedical data. CGM provides rich, temporal data on glycemic patterns, but its full…

Blood glucose (BG) management is crucial for type-1 diabetes patients resulting in the necessity of reliable artificial pancreas or insulin infusion systems. In recent years, deep learning techniques have been utilized for a more accurate…

Machine Learning · Computer Science 2021-01-19 Md Fazle Rabby , Yazhou Tu , Md Imran Hossen , Insup Le , Anthony S Maida , Xiali Hei

In the UK, approximately 400,000 people with type 1 diabetes (T1D) rely on insulin delivery due to insufficient pancreatic insulin production. Managing blood glucose (BG) levels is crucial, with continuous glucose monitoring (CGM) playing a…

Machine Learning · Computer Science 2023-12-21 Chengzhe Piao , Ken Li

Understanding how biomarker distributions evolve over time is a central challenge in digital health and chronic disease monitoring. In diabetes, changes in the distribution of glucose measurements can reveal patterns of disease progression…

Machine Learning · Statistics 2026-03-26 Antonio Álvarez-López , Marcos Matabuena

Diabetes mellitus (DM) is a global health issue of significance that must be diagnosed as early as possible and managed well. This study presents a framework for diabetes prediction using Machine Learning (ML) models, complemented with…

Machine Learning · Computer Science 2025-02-13 Pir Bakhsh Khokhar , Viviana Pentangelo , Fabio Palomba , Carmine Gravino

Diabetes is a chronicle disease where the body of a human is irregular to dissolve the blood glucose properly. The diabetes is due to lack of insulin in human body. The continuous monitoring of blood glucose is main important aspect for…

Medical Physics · Physics 2021-06-10 Prateek Jain , Amit M. Joshi , Saraju Mohanty

Diabetes Mellitus is a metabolic disorder which may result in severe and potentially fatal complications if not well-treated and monitored. In this study, a quantitative analysis of the data collected using CGM (Continuous Glucose…

Quantitative Methods · Quantitative Biology 2023-08-15 Giulia Elena Aliffi , Giovanni Nastasi , Vittorio Romano , Dario Pitocco , Alessandro Rizzi , Elvin J. Moore , Andrea De Gaetano

Continuous Glucose Monitoring (CGM) has enabled important opportunities for diabetes management. This study explores the use of CGM data as input for digital decision support tools. We investigate how Recurrent Neural Networks (RNNs) can be…