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For the Research Topic Data Assimilation and Control: Theory and Applications in Life Sciences we first review the formulation of statistical data assimilation (SDA) and discuss algorithms for exploring variational approximations to the…

Neurons and Cognition · Quantitative Biology 2018-09-17 Anna Miller , Dawei Li , Jason Platt , Arij Daou , Daniel Margoliash , Henry Abarbanel

This paper considers a class of real-time stochastic optimization problems dependent on an unknown probability distribution. In the considered scenario, data is streaming frequently while trying to reach a decision. Thus, we aim to devise a…

Optimization and Control · Mathematics 2020-09-08 Dan Li , Sonia Martinez

Reduced-order modelling and low-dimensional surrogate models generated using machine learning algorithms have been widely applied in high-dimensional dynamical systems to improve the algorithmic efficiency. In this paper, we develop a…

We propose, analyze, and test a novel continuous data assimilation reduced order model (DA-ROM) for simulating incompressible flows. While ROMs have a long history of success on certain problems with recurring dominant structures, they tend…

Numerical Analysis · Mathematics 2019-10-02 Camille Zerfas , Leo G. Rebholz , Michael Schneier , Traian Iliescu

Autonomous agents for Graphical User Interfaces (GUIs) face significant challenges in specialized domains such as scientific computing, where both long-horizon planning and precise execution are required. Existing approaches suffer from a…

Computer Vision and Pattern Recognition · Computer Science 2025-08-28 Zeyi Sun , Yuhang Cao , Jianze Liang , Qiushi Sun , Ziyu Liu , Zhixiong Zhang , Yuhang Zang , Xiaoyi Dong , Kai Chen , Dahua Lin , Jiaqi Wang

Data assimilation (DA) is a fundamental computational technique that integrates numerical simulation models and observation data on the basis of Bayesian statistics. Originally developed for meteorology, especially weather forecasting, DA…

Accurate knowledge of the state variables in a dynamical system is critical for effective control, diagnosis, and supervision, especially when direct measurements of all states are infeasible. This paper presents a novel approach to…

Dynamical Systems · Mathematics 2025-07-10 Ayoub Farkane , Mohamed Boutayeb , Mustapha Oudani , Mounir Ghogho

Dynamic optimization problems involving discrete decisions have several applications, yet lead to challenging optimization problems that must be addressed efficiently. Combining discrete variables with potentially nonlinear constraints…

Optimization and Control · Mathematics 2024-09-17 Zedong Peng , Albert Lee , David E. Bernal Neira

Automated machine learning (AutoML) usually involves several crucial components, such as Data Augmentation (DA) policy, Hyper-Parameter Optimization (HPO), and Neural Architecture Search (NAS). Although many strategies have been developed…

Machine Learning · Computer Science 2023-03-31 Kaichen Zhou , Lanqing Hong , Shoukang Hu , Fengwei Zhou , Binxin Ru , Jiashi Feng , Zhenguo Li

Sparse Identification of Nonlinear Dynamics (SINDy) has been shown to successfully recover governing equations from data; however, this approach assumes the initial condition to be exactly known in advance and is sensitive to noise. In this…

Dynamical Systems · Mathematics 2022-11-23 Baolei Wei

Neural Ordinary Differential Equations (NODEs) have proven successful in learning dynamical systems in terms of accurately recovering the observed trajectories. While different types of sparsity have been proposed to improve robustness, the…

Machine Learning · Computer Science 2022-10-27 Hananeh Aliee , Till Richter , Mikhail Solonin , Ignacio Ibarra , Fabian Theis , Niki Kilbertus

Continuous data assimilation (CDA) techniques, most notably the nudging approach proposed by Azouani, Olson, and Titi (AOT), have been shown to be very successful in deterministic frameworks for achieving long-time synchronization between…

Probability · Mathematics 2026-04-20 Kush Kinra

Predictive simulations of complex systems are essential for applications ranging from weather forecasting to drug design. The veracity of these predictions hinges on their capacity to capture the effective system dynamics. Massively…

Computational Physics · Physics 2021-10-20 Pantelis R. Vlachas , Georgios Arampatzis , Caroline Uhler , Petros Koumoutsakos

End-to-End paradigms use a unified framework to implement multi-tasks in an autonomous driving system. Despite simplicity and clarity, the performance of end-to-end autonomous driving methods on sub-tasks is still far behind the single-task…

This article develops a novel data assimilation methodology, addressing challenges that are common in real-world settings, such as severe sparsity of observations, lack of reliable models, and non-stationarity of the system dynamics. These…

Optimization and Control · Mathematics 2024-11-05 David J. Abers , George Hripcsak , Lena Mamykina , Melike Sirlanci , Esteban G. Tabak

Sparse identification of nonlinear dynamics (SINDy) has been widely used to discover the governing equations of a dynamical system from data. It uses sparse regression techniques to identify parsimonious models of unknown systems from a…

Methodology · Statistics 2026-04-07 Kairui Ding

Data assimilation techniques are crucial for accurately tracking complex dynamical systems by integrating observational data with numerical forecasts. Recently, score-based data assimilation methods emerged as powerful tools for…

Machine Learning · Statistics 2026-03-03 Pengpeng Xiao , Phillip Si , Peng Chen

Learning predictive models from observations using deep neural networks (DNNs) is a promising new approach to many real-world planning and control problems. However, common DNNs are too unstructured for effective planning, and current…

Robotics · Computer Science 2023-12-21 Ziang Liu , Genggeng Zhou , Jeff He , Tobia Marcucci , Li Fei-Fei , Jiajun Wu , Yunzhu Li

In this work we propose the use of adaptive stochastic search as a building block for general, non-convex optimization operations within deep neural network architectures. Specifically, for an objective function located at some layer in the…

Machine Learning · Computer Science 2021-04-05 Ioannis Exarchos , Marcus A. Pereira , Ziyi Wang , Evangelos A. Theodorou

Scientific machine learning is an emerging field that broadly describes the combination of scientific computing and machine learning to address challenges in science and engineering. Within the context of differential equations, this has…

Machine Learning · Computer Science 2026-04-03 Laurens R. Lueg , Victor Alves , Daniel Schicksnus , John R. Kitchin , Carl D. Laird , Lorenz T. Biegler