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Due to the intrinsic complexity and nonlinearity of chemical reactions, direct applications of traditional machine learning algorithms may face with many difficulties. In this study, through two concrete examples with biological background,…

Molecular Networks · Quantitative Biology 2020-06-02 Wuyue Yang , Liangrong Peng , Yi Zhu , Liu Hong

Data sharing issues pervade online social and economic environments. To foster social progress, it is important to develop models of the interaction between data producers and consumers that can promote the rise of cooperation between the…

Computer Science and Game Theory · Computer Science 2021-01-27 Víctor Gallego , Roi Naveiro , David Ríos Insua , Wolfram Rozas

Large Language Models (LLMs) have been adopted and deployed worldwide for a broad variety of applications. However, ensuring their safe use remains a significant challenge. Preference training and safety measures often overfit to harms…

Computation and Language · Computer Science 2024-10-15 Aakanksha , Arash Ahmadian , Seraphina Goldfarb-Tarrant , Beyza Ermis , Marzieh Fadaee , Sara Hooker

For robots to be a part of our daily life, they need to be able to navigate among crowds not only safely but also in a socially compliant fashion. This is a challenging problem because humans tend to navigate by implicitly cooperating with…

Robotics · Computer Science 2017-05-18 Anirudh Vemula , Katharina Muelling , Jean Oh

While much has been learnt about the impacts of specific stressors on individual marine organisms, considerable debate exists over the nature and impact of multiple simultaneous stressors on both individual species and marine ecosystems. We…

Populations and Evolution · Quantitative Biology 2019-07-23 Richard Bailey , Jesse van der Grient

This paper presents an integrated framework that combines traditional network optimization models with large language models (LLMs) to deliver interactive, explainable, and role-aware decision support for supply chain planning. The proposed…

Artificial Intelligence · Computer Science 2025-09-01 Saravanan Venkatachalam

Various data modalities are common in real-world applications (e.g., electronic health records, medical images and clinical notes in healthcare). It is essential to develop multimodal learning methods to aggregate various information from…

Machine Learning · Computer Science 2025-11-06 Feng Wu , Tsai Hor Chan , Fuying Wang , Guosheng Yin , Lequan Yu

We develop a hybrid control approach for robot learning based on combining learned predictive models with experience-based state-action policy mappings to improve the learning capabilities of robotic systems. Predictive models provide an…

Robotics · Computer Science 2020-06-09 Ian Abraham , Alexander Broad , Allison Pinosky , Brenna Argall , Todd D. Murphey

Learning efficiently a causal model of the environment is a key challenge of model-based RL agents operating in POMDPs. We consider here a scenario where the learning agent has the ability to collect online experiences through direct…

Machine Learning · Computer Science 2021-06-29 Maxime Gasse , Damien Grasset , Guillaume Gaudron , Pierre-Yves Oudeyer

This article will summarize the workshop proceedings of a workshop conducted at the University of Missouri that addressed the use of multi-omics fused with geospatial information to assess and improve the precision and environmental…

Large language models (LLMs) have shown remarkable promise but remain challenging to continually improve through traditional finetuning, particularly when integrating capabilities from other specialized LLMs. Popular methods like ensemble…

Computation and Language · Computer Science 2025-06-02 Zhenglun Kong , Zheng Zhan , Shiyue Hou , Yifan Gong , Xin Meng , Pengwei Sui , Peiyan Dong , Xuan Shen , Zifeng Wang , Pu Zhao , Hao Tang , Stratis Ioannidis , Yanzhi Wang

While there is evidence that user-adaptive support can greatly enhance the effectiveness of educational systems, designing such support for exploratory learning environments (e.g., simulations) is still challenging due to the open-ended…

Artificial Intelligence · Computer Science 2021-06-15 Sébastien Lallé , Cristina Conati

Extracting biomedical relations from large corpora of scientific documents is a challenging natural language processing task. Existing approaches usually focus on identifying a relation either in a single sentence (mention-level) or across…

Computation and Language · Computer Science 2020-11-23 Harshil Shah , Julien Fauqueur

In an effort to effectively model observed patterns in the spatial configuration of individuals of multiple species in nature, we introduce the saturated pairwise interaction Gibbs point process. Its main strength lies in its ability to…

Methodology · Statistics 2023-02-27 Ian Flint , Nick Golding , Peter Vesk , Yan Wang , Aihua Xia

Self-interested individuals often fail to cooperate, posing a fundamental challenge for multi-agent learning. How can we achieve cooperation among self-interested, independent learning agents? Promising recent work has shown that in certain…

Motion planning is a crucial component of autonomous robot driving. While various trajectory datasets exist, effectively utilizing them for a target domain remains challenging due to differences in agent interactions and environmental…

Robotics · Computer Science 2025-07-28 Giwon Lee , Wooseong Jeong , Daehee Park , Jaewoo Jeong , Kuk-Jin Yoon

Recent advances in biological research have seen the emergence of high-throughput technologies with numerous applications that allow the study of biological mechanisms at an unprecedented depth and scale. A large amount of genomic data is…

Machine Learning · Statistics 2020-05-11 Nanwei Wang , Laurent Briollais , Helene Massam

Translating the vast data generated by genomic platforms into reliable predictions of clinical outcomes remains a critical challenge in realizing the promise of genomic medicine largely due to small number of independent samples. In this…

Quantitative Methods · Quantitative Biology 2019-04-04 Safoora Yousefi , Amirreza Shaban , Mohamed Amgad , Ramraj Chandradevan , Lee A. D. Cooper

Modeling complex systems is a time-consuming, difficult and fragmented task, often requiring the analyst to work with disparate data, a variety of models, and expert knowledge across a diverse set of domains. Applying a user-centered design…

Human-Computer Interaction · Computer Science 2021-09-09 Fahd Husain , Pascale Proulx , Meng-Wei Chang , Rosa Romero-Gomez , Holland Vasquez

Identifying potential drug targets using metabolic modeling requires integrating multiple modeling methods and heterogenous biological datasets, which can be challenging without sophisticated tools. We developed COMO, a user-friendly…

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