Related papers: RATNUS: Rapid, Automatic Thalamic Nuclei Segmentat…
Accurate segmentation of thalamic nuclei from magnetic resonance images is important due to the distinct roles of these nuclei in overall brain function and to their differential involvement in neurological and psychiatric disorders.…
The human thalamus is a highly connected subcortical grey-matter structure within the brain. It comprises dozens of nuclei with different function and connectivity, which are affected differently by disease. For this reason, there is…
The implication of the thalamus in multiple neurological pathologies makes it a structure of interest for volumetric analysis. In the present work, we have designed and implemented a multimodal volumetric deep neural network for the…
Accurate thalamic nuclei segmentation is crucial for understanding neurological diseases, brain functions, and guiding clinical interventions. However, the optimal inputs for segmentation remain unclear. This study systematically evaluates…
The thalamus and its constituent nuclei are critical for a broad range of cognitive and sensorimotor processes, and implicated in many neurological and neurodegenerative conditions. However, the functional involvement and specificity of…
Accurate segmentation of thalamic nuclei, crucial for understanding their role in healthy cognition and in pathologies, is challenging to achieve on standard T1-weighted (T1w) magnetic resonance imaging (MRI) due to poor image contrast.…
The thalamus is a subcortical gray matter structure that plays a key role in relaying sensory and motor signals within the brain. Its nuclei can atrophy or otherwise be affected by neurological disease and injuries including mild traumatic…
A cascaded multi-planar scheme with a modified residual U-Net architecture was used to segment thalamic nuclei on conventional and white-matter-nulled (WMn) magnetization prepared rapid gradient echo (MPRAGE) data. A single network was…
Thalamic alterations are relevant to many neurological disorders including Alzheimer's disease, Parkinson's disease and multiple sclerosis. Routine interventions to improve symptom severity in movement disorders, for example, often consist…
The thalamus is a subcortical structure of central importance to brain function, which is organized in smaller nuclei with specialized roles. Despite significant functional and clinical relevance, locating and distinguishing the different…
Purpose: Thalamic nuclei are largely invisible in conventional MRI due to poor contrast. Thalamus Optimized Multi-Atlas Segmentation (THOMAS) provides automatic segmentation of 12 thalamic nuclei using white-matter-nulled (WMn) MPRAGE…
Motivation: Lack of tools for comprehensive and complete segmentation of deep grey nuclei using a single software for reproducibility and repeatability Goal(s): A fast accurate and robust method for segmentation of deep grey nuclei…
Thalamic nuclei have been implicated in several neurological diseases. WMn-MPRAGE images have been shown to provide better intra-thalamic nuclear contrast compared to conventional MPRAGE images but the additional acquisition results in…
The thalamus consists of several histologically and functionally distinct nuclei increasingly implicated in brain pathology and important for treatment, motivating the need for development of fast and accurate thalamic segmentation. The…
The diagnosis and segmentation of tumors using any medical diagnostic tool can be challenging due to the varying nature of this pathology. Magnetic Reso- nance Imaging (MRI) is an established diagnostic tool for various diseases and…
The human thalamus is a brain structure that comprises numerous, highly specific nuclei. Since these nuclei are known to have different functions and to be connected to different areas of the cerebral cortex, it is of great interest for the…
This paper proposes LiNUS, a lightweight deep learning framework for the automatic segmentation of the Subthalamic Nucleus (STN) in Deep Brain Stimulation (DBS) surgery. Addressing the challenges of small target volume and class imbalance…
Brain tissue segmentation has demonstrated great utility in quantifying MRI data through Voxel-Based Morphometry and highlighting subtle structural changes associated with various conditions within the brain. However, manual segmentation is…
Segmentation of structural and diffusion MRI (sMRI/dMRI) is usually performed independently in neuroimaging pipelines. However, some brain structures (e.g., globus pallidus, thalamus and its nuclei) can be extracted more accurately by…
Nucleus image segmentation is a crucial step in the analysis, pathological diagnosis, and classification, which heavily relies on the quality of nucleus segmentation. However, the complexity of issues such as variations in nucleus size,…