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To address prevalent issues in medical imaging, such as data acquisition challenges and label availability, transfer learning from natural to medical image domains serves as a viable strategy to produce reliable segmentation results.…

Image and Video Processing · Electrical Eng. & Systems 2023-11-15 Hao Li , Han Liu , Dewei Hu , Jiacheng Wang , Ipek Oguz

Segment Anything Models (SAMs) like SEEM and SAM have demonstrated great potential in learning to segment anything. The core design of SAMs lies with Promptable Segmentation, which takes a handcrafted prompt as input and returns the…

Computer Vision and Pattern Recognition · Computer Science 2024-01-10 Jiaxing Huang , Kai Jiang , Jingyi Zhang , Han Qiu , Lewei Lu , Shijian Lu , Eric Xing

The Segment Anything Model (SAM) has demonstrated strong and versatile segmentation capabilities, along with intuitive prompt-based interactions. However, customizing SAM for medical image segmentation requires massive amounts of…

Computer Vision and Pattern Recognition · Computer Science 2025-01-14 Zhonghao Yan , Zijin Yin , Tianyu Lin , Xiangzhu Zeng , Kongming Liang , Zhanyu Ma

The Segment Anything Model 2 (SAM2) has demonstrated remarkable promptable visual segmentation capabilities in video data, showing potential for extension to medical image segmentation (MIS) tasks involving 3D volumes and temporally…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Meng Lan , Lefei Zhang , Xiaomeng Li

Promptable segmentation foundation models such as SAM3 have demonstrated strong generalization capabilities through interactive and concept-based prompting. However, their direct applicability to medical image segmentation remains limited…

Computer Vision and Pattern Recognition · Computer Science 2026-01-19 Chongcong Jiang , Tianxingjian Ding , Chuhan Song , Jiachen Tu , Ziyang Yan , Yihua Shao , Zhenyi Wang , Yuzhang Shang , Tianyu Han , Yu Tian

End-to-end medical image segmentation is of great value for computer-aided diagnosis dominated by task-specific models, usually suffering from poor generalization. With recent breakthroughs brought by the segment anything model (SAM) for…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Xian Lin , Yangyang Xiang , Li Yu , Zengqiang Yan

The Segment Anything Model (SAM) can achieve satisfactory segmentation performance under high-quality box prompts. However, SAM's robustness is compromised by the decline in box quality, limiting its practicality in clinical reality. In…

Computer Vision and Pattern Recognition · Computer Science 2024-08-01 Yuhao Huang , Xin Yang , Han Zhou , Yan Cao , Haoran Dou , Fajin Dong , Dong Ni

Intelligent medical image segmentation methods are rapidly evolving and being increasingly applied, yet they face the challenge of domain transfer, where algorithm performance degrades due to different data distributions between source and…

Computer Vision and Pattern Recognition · Computer Science 2024-08-12 Andrew Seohwan Yu , Mohsen Hariri , Xuecen Zhang , Mingrui Yang , Vipin Chaudhary , Xiaojuan Li

Segment Anything Model 2 (SAM2) demonstrated impressive zero-shot capabilities on natural images but faces challenges in biomedical segmentation due to significant domain shifts and prompt dependency. To address these limitations, we…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Hinako Mitsuoka , Kazuhiro Hotta

The Segment Anything Model (SAM) is widely used for segmenting a diverse range of objects in natural images from simple user prompts like points or bounding boxes. However, SAM's performance decreases substantially when applied to…

Computer Vision and Pattern Recognition · Computer Science 2025-04-24 Tristan Piater , Björn Barz , Alexander Freytag

Medical images often exhibit distribution shifts due to variations in imaging protocols and scanners across different medical centers. Domain Generalization (DG) methods aim to train models on source domains that can generalize to unseen…

Computer Vision and Pattern Recognition · Computer Science 2024-11-18 Yihang Fu , Ziyang Chen , Yiwen Ye , Xingliang Lei , Zhisong Wang , Yong Xia

We propose a straightforward yet highly effective few-shot fine-tuning strategy for adapting the Segment Anything (SAM) to anatomical segmentation tasks in medical images. Our novel approach revolves around reformulating the mask decoder…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Weiyi Xie , Nathalie Willems , Shubham Patil , Yang Li , Mayank Kumar

Foundation models, such as the Segment Anything Model (SAM), have heightened interest in promptable zero-shot segmentation. Although these models perform strongly on natural images, their behavior on medical data remains insufficiently…

Image and Video Processing · Electrical Eng. & Systems 2026-04-07 Satrajit Chakrabarty , Ravi Soni

Segment Anything Model (SAM) has gained significant recognition in the field of semantic segmentation due to its versatile capabilities and impressive performance. Despite its success, SAM faces two primary limitations: (1) it relies…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Yuchen Li , Li Zhang , Youwei Liang , Pengtao Xie

The development of machine learning models for CT imaging depends on the availability of large, high-quality, and diverse annotated datasets. Although large volumes of CT images and reports are readily available in clinical picture…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Samuel Church , Joshua D. Warner , Danyal Maqbool , Xin Tie , Junjie Hu , Meghan G. Lubner , Tyler J. Bradshaw

The recent Segment Anything Model (SAM) 2 has demonstrated remarkable foundational competence in semantic segmentation, with its memory mechanism and mask decoder further addressing challenges in video tracking and object occlusion, thereby…

Computer Vision and Pattern Recognition · Computer Science 2024-08-09 Jieming Yu , An Wang , Wenzhen Dong , Mengya Xu , Mobarakol Islam , Jie Wang , Long Bai , Hongliang Ren

The limited availability of labeled data has driven advancements in semi-supervised learning for medical image segmentation. Modern large-scale models tailored for general segmentation, such as the Segment Anything Model (SAM), have…

Computer Vision and Pattern Recognition · Computer Science 2024-12-19 Kaiwen Huang , Tao Zhou , Huazhu Fu , Yizhe Zhang , Yi Zhou , Chen Gong , Dong Liang

The Segment Anything Model (SAM) made an eye-catching debut recently and inspired many researchers to explore its potential and limitation in terms of zero-shot generalization capability. As the first promptable foundation model for…

Computer Vision and Pattern Recognition · Computer Science 2023-05-02 Dongjie Cheng , Ziyuan Qin , Zekun Jiang , Shaoting Zhang , Qicheng Lao , Kang Li

We present SAM4EM, a novel approach for 3D segmentation of complex neural structures in electron microscopy (EM) data by leveraging the Segment Anything Model (SAM) alongside advanced fine-tuning strategies. Our contributions include the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-01 Uzair Shah , Marco Agus , Daniya Boges , Vanessa Chiappini , Mahmood Alzubaidi , Jens Schneider , Markus Hadwiger , Pierre J. Magistretti , Mowafa Househ , Corrado Calı

The Segment Anything Model (SAM) is a recently developed all-range foundation model for image segmentation. It can use sparse manual prompts such as bounding boxes to generate pixel-level segmentation in natural images but struggles in…

Computer Vision and Pattern Recognition · Computer Science 2023-08-22 Xing Yao , Han Liu , Dewei Hu , Daiwei Lu , Ange Lou , Hao Li , Ruining Deng , Gabriel Arenas , Baris Oguz , Nadav Schwartz , Brett C Byram , Ipek Oguz