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Heat-based cancer treatment, so-called hyperthermia, can be used to destroy tumour cells directly or to make them more susceptible to chemotherapy or radiation therapy. To apply heat locally, iron oxide nanoparticles are injected into the…

Computational Engineering, Finance, and Science · Computer Science 2025-02-04 Barbara Wirthl , Paolo Decuzzi , Bernhard A. Schrefler , Wolfgang A. Wall

One-dimensional (1D) blood flow simulations are extensively used in cardiovascular research due to their computational efficiency and effectiveness in analyzing pulse wave dynamics. Despite their versatility and simplicity, there is a lack…

Quantitative Methods · Quantitative Biology 2025-08-27 Daehyun Kim , Jeffrey Tithof

We present a unified mathematical framework for modeling blood and lymph flow in biological vessels, with a particular focus on lymph transport through lymphangions. Starting from first principles, we rigorously derive a system of partial…

Analysis of PDEs · Mathematics 2026-03-03 Bogna Jaszczak-Dyka , Łukasz Płociniczak

In the present paper we propose a reduced temperature non-equilibrium model for simulating multicomponent flows with inter-phase heat transfer, diffusion processes (including the viscosity and the heat conduction) and external energy…

Numerical Analysis · Mathematics 2021-08-19 Chao Zhang , Lifeng Wang , Zhijun Shen , Zhiyuan Li , Igor Menshov

The discrete element method (DEM) coupled with computational fluid dynamics (CFD), has been developed to simulate complex solid-fluid flow systems. Today, DEM is regarded as an established approach, with extensive applications in industrial…

Fluid Dynamics · Physics 2025-10-16 Toshiki Imatani , Mikio Sakai

Homogenization method is used to analyse the equivalent behavior of transient flow of a passive solute through highly heterogeneous porous media. The flow is governed by a coupled system which includes an elliptic equation and a linear…

Mathematical Physics · Physics 2007-05-23 Brahim Amaziane , Alain Bourgeat , Mladen Jurak

We present a novel hybrid incompressible flow/material point method solver for simulating the combustion of flammable solids. Our approach utilizes a sparse grid representation of solid materials in the material point method portion of the…

Graphics · Computer Science 2024-08-15 Victoria Kala , Jingyu Chen , David Hyde , Alexey Stomakhin , Joseph Teran

Altered hemodynamics play a key role in cerebrovascular diseases such as aneurysms and stenosis. However, in vivo imaging lacks the spatial resolution required to resolve flow dynamics in small vessels. This study presents an experimental…

Fluid Dynamics · Physics 2026-05-25 Job van Essen , Ahmed Sharaf , Denzel Hopman , Selene Pirola , Paola Fanzio

The use of nanoparticles for targeted drug delivery, especially in diseased arteries, is a novel procedure. We are incorporating nanoparticles into blood vessels using a catheter, which could potentially deliver drugs precisely to affected…

Fluid Dynamics · Physics 2023-08-31 Surabhi Rathore , Dasari Srikanth

We propose and analyze a family of models describing blood perfusion through a tissue surrounding a thin blood vessel. Our goal is to rigorously establish convergence results among 3D-3D Darcy--Stokes, 3D-1D Darcy--Poiseuille, and 1D…

Analysis of PDEs · Mathematics 2025-07-18 Laurel Ohm , Sarah Strikwerda

A comprehensive understanding of heat transfer mechanisms in biological tissues is essential for the advancement of thermal therapeutic techniques and the development of accurate bioheat transfer models. Conventional models often fail to…

Accurate prediction of electron temperature ($T_{\rm e}$) in non-equilibrium {plasma} flows is critical, yet hampered by inadequate models for electron heating from vibrationally excited states. Prior models often relied on ad-hoc scaling…

Plasma Physics · Physics 2025-09-23 Felipe Martin Rodriguez Fuentes , Bernard Parent

Subject-specific modeling is a powerful tool in cardiovascular research, providing insights beyond the reach of current clinical diagnostics. Limitations in available clinical data require the incorporation of uncertainty into models to…

Applications · Statistics 2025-07-16 Amirreza Kachabi , Sofia Altieri Correa , Naomi C. Chesler , Mitchel J. Colebank

Hemodynamic quantities are valuable biomedical risk factors for cardiovascular pathology such as atherosclerosis. Non-invasive, in-vivo measurement of these quantities can only be performed using a select number of modalities that are not…

Quantitative Methods · Quantitative Biology 2026-02-23 Julian Suk , Dieuwertje Alblas , Barbara A. Hutten , Albert Wiegman , Christoph Brune , Pim van Ooij , Jelmer M. Wolterink

Batteries are critical for electrified transportation and aviation, yet thermodynamic understanding of electrode materials remains lacking, as indicated by the often-seen violation of the second law of thermodynamics of open-circuit voltage…

Chemical Physics · Physics 2025-07-16 Archie Mingze Yao , Amal Sebastian , Venkatasubramaian Viswanathan

The development of blood-handling medical devices, such as ventricular assist devices, requires the analysis of their biocompatibility. Among other aspects, this includes hemolysis, i.e., red blood cell damage. For this purpose,…

Fluid Dynamics · Physics 2024-04-15 Nico Dirkes , Fabian Key , Marek Behr

We numerically investigate turbulent Rayleigh-B\'enard convection with gas bubbles attached to the hot plate, mimicking a core feature in electrolysis, catalysis, or boiling. The existence of bubbles on the plate reduces the global heat…

Fluid Dynamics · Physics 2022-08-17 Hao-Ran Liu , Kai Leong Chong , Rui Yang , Roberto Verzicco , Detlef Lohse

The last years saw a renewal of interest for hypersonic research in general and regenerative cooling specifically, with a large increase of the number of dedicated facilities and technical studies. In order to quantify the heat transfer in…

The emergence of computational fluid dynamics (CFD) enabled the simulation of intricate transport processes, including flow in physiological structures, such as blood vessels. While these so-called hemodynamic simulations offer…

Image-based computational fluid dynamics (CFD) has emerged as a powerful tool to study cardiovascular flows while 2D echocardiography (echo) is the most widely used non-invasive imaging modality for diagnosis of heart disease. Here, echo is…