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This study advances Early Event Prediction (EEP) in healthcare through Dynamic Survival Analysis (DSA), offering a novel approach by integrating risk localization into alarm policies to enhance clinical event metrics. By adapting and…

Machine Learning · Computer Science 2024-03-20 Hugo Yèche , Manuel Burger , Dinara Veshchezerova , Gunnar Rätsch

Estimating risks or survival probabilities conditional on individual characteristics based on censored time-to-event data is a commonly faced task. This may be for the purpose of developing a prediction model or may be part of a wider…

Accurate prediction of disease trajectories is critical for early identification and timely treatment of patients at risk. Conventional methods in survival analysis are often constrained by strong parametric assumptions and limited in their…

Machine Learning · Computer Science 2018-11-28 Daniel Jarrett , Jinsung Yoon , Mihaela van der Schaar

Suppression of disability progression is an important goal in the treatment of multiple sclerosis (MS). Randomized clinical trials in MS frequently use the time to the first confirmed disability progression (CDP) on the ordinal Expanded…

Applications · Statistics 2021-11-04 Alexandra Būhler

In this paper, we develop a novel logic-based approach to detecting high-level temporally extended events from timestamped data and background knowledge. Our framework employs logical rules to capture existence and termination conditions…

Artificial Intelligence · Computer Science 2026-04-24 Yvon K. Awuklu , Meghyn Bienvenu , Katsumi Inoue , Vianney Jouhet , Fleur Mougin

This study explores the application of self-supervised learning techniques for event sequences. It is a key modality in various applications such as banking, e-commerce, and healthcare. However, there is limited research on self-supervised…

Although recent multi-task learning methods have shown to be effective in improving the generalization of deep neural networks, they should be used with caution for safety-critical applications, such as clinical risk prediction. This is…

Machine Learning · Computer Science 2021-02-19 A. Tuan Nguyen , Hyewon Jeong , Eunho Yang , Sung Ju Hwang

In many clinical trials studying neurodegenerative diseases such as Parkinson's disease (PD), multiple longitudinal outcomes are collected to fully explore the multidimensional impairment caused by this disease. If the outcomes deteriorate…

Applications · Statistics 2017-05-18 Jue Wang , Sheng Luo , Liang Li

Causal inference across multiple data sources offers a promising avenue to enhance the generalizability and replicability of scientific findings. However, data integration methods for time-to-event outcomes, common in biomedical research,…

Methodology · Statistics 2025-05-16 Yi Liu , Alexander W. Levis , Ke Zhu , Shu Yang , Peter B. Gilbert , Larry Han

Survival regression is widely used to model time-to-events data, to explore how covariates may influence the occurrence of events. Modern datasets often encompass a vast number of covariates across many subjects, with only a subset of the…

Methodology · Statistics 2024-09-18 Abhishek Mandal , Abhisek Chakraborty

With the rapid advances of deep learning, many computational methods have been developed to analyze nonlinear and complex right censored data via deep learning approaches. However, the majority of the methods focus on predicting survival…

Machine Learning · Computer Science 2022-02-11 Jong-Hyeon Jeong , Yichen Jia

Network meta-analysis (NMA) of rare events has attracted little attention in the literature. Until recently, networks of interventions with rare events were analyzed using the inverse-variance NMA approach. However, when events are rare the…

Methodology · Statistics 2021-09-22 Theodoros Evrenoglou , Ian White , Sivem Afach , Dimitris Mavridis , Anna Chaimani

In epidemiological research, modeling the cumulative effects of time-dependent exposures on survival outcomes presents a challenge due to their intricate temporal dynamics. Conventional spline-based statistical methods, though effective,…

Machine Learning · Computer Science 2026-01-01 Kang-Chung Yang , Shinsheng Yuan

Complex systems display emergent phenomena that vary significantly across spatial and temporal scales. These variations originate from fine-grained system processes, yet arriving at macroscopic dynamics from micro-level data -- particularly…

Urban dispersal events are processes where an unusually large number of people leave the same area in a short period. Early prediction of dispersal events is important in mitigating congestion and safety risks and making better dispatching…

Machine Learning · Computer Science 2019-07-12 Amin Vahedian , Xun Zhou , Ling Tong , W. Nick Street , Yanhua Li

The large volumes of data generated by human activities such as online purchases, health records, spatial mobility etc. are stored as a sequence of events over a continuous time. Learning deep learning methods over such sequences is a…

Machine Learning · Computer Science 2021-11-16 Vinayak Gupta

Understanding natural language involves recognizing how multiple event mentions structurally and temporally interact with each other. In this process, one can induce event complexes that organize multi-granular events with temporal order…

Computation and Language · Computer Science 2021-05-04 Haoyu Wang , Muhao Chen , Hongming Zhang , Dan Roth

Stochastic compartmental models are prevalent tools for describing disease spread, but inference under these models is challenging for many types of surveillance data when the marginal likelihood function becomes intractable due to missing…

Methodology · Statistics 2026-02-05 Suchismita Roy , Alexander A. Fisher , Jason Xu

Joint models for longitudinal and time-to-event data are commonly used in longitudinal studies to forecast disease trajectories over time. While there are many advantages to joint modeling, the standard forms suffer from limitations that…

Machine Learning · Statistics 2019-09-09 Bryan Lim , Mihaela van der Schaar

Survival analysis in the presence of multiple possible adverse events, i.e., competing risks, is a pervasive problem in many industries (healthcare, finance, etc.). Since only one event is typically observed, the incidence of an event of…

Machine Learning · Computer Science 2018-08-20 Anton Nemchenko , Trent Kyono , Mihaela Van Der Schaar