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Auto-encoding generative adversarial networks (GANs) combine the standard GAN algorithm, which discriminates between real and model-generated data, with a reconstruction loss given by an auto-encoder. Such models aim to prevent mode…

Machine Learning · Statistics 2017-10-24 Mihaela Rosca , Balaji Lakshminarayanan , David Warde-Farley , Shakir Mohamed

We present a generative modeling approach based on the variational inference framework for likelihood-free simulation-based inference. The method leverages latent variables within variational autoencoders to efficiently estimate complex…

Machine Learning · Computer Science 2025-10-20 Mayank Nautiyal , Andrey Shternshis , Andreas Hellander , Prashant Singh

We consider multi-solution optimization and generative models for the generation of diverse artifacts and the discovery of novel solutions. In cases where the domain's factors of variation are unknown or too complex to encode manually,…

Machine Learning · Computer Science 2021-05-11 Alexander Hagg , Sebastian Berns , Alexander Asteroth , Simon Colton , Thomas Bäck

Variational autoencoders have been widely applied for natural language generation, however, there are two long-standing problems: information under-representation and posterior collapse. The former arises from the fact that only the last…

Machine Learning · Computer Science 2021-06-17 Xianghong Fang , Haoli Bai , Zenglin Xu , Michael Lyu , Irwin King

Recent advances in denoising diffusion probabilistic models have shown great success in image synthesis tasks. While there are already works exploring the potential of this powerful tool in image semantic segmentation, its application in…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Xinrong Hu , Yu-Jen Chen , Tsung-Yi Ho , Yiyu Shi

Therapeutic antibodies require not only high-affinity target engagement, but also favorable manufacturability, stability, and safety profiles for clinical effectiveness. These properties are collectively called `developability'. To enable a…

Machine Learning · Computer Science 2025-07-04 Siqi Zhao , Joshua Moller , Porfi Quintero-Cadena , Lood van Niekerk

Recent improvements in conditional generative modeling have made it possible to generate high-quality images from language descriptions alone. We investigate whether these methods can directly address the problem of sequential…

Machine Learning · Computer Science 2023-07-11 Anurag Ajay , Yilun Du , Abhi Gupta , Joshua Tenenbaum , Tommi Jaakkola , Pulkit Agrawal

The aim of global optimization is to find the global optimum of arbitrary classes of functions, possibly highly multimodal ones. In this paper we focus on the subproblem of global optimization for differentiable functions and we propose an…

Neural and Evolutionary Computing · Computer Science 2018-06-18 Louis Faury , Flavian Vasile , Clément Calauzènes , Olivier Fercoq

Estimating causal effects from observational data (at either an individual -- or a population -- level) is critical for making many types of decisions. One approach to address this task is to learn decomposed representations of the…

Machine Learning · Computer Science 2021-11-15 Negar Hassanpour , Russell Greiner

Reliable training of generative adversarial networks (GANs) typically require massive datasets in order to model complicated distributions. However, in several applications, training samples obey invariances that are \textit{a priori}…

The ability to accurately model random fields plays a critical role in science and engineering for problems involving uncertain, spatially-varying quantities such as heterogeneous material properties and turbulent flows. Deep generative…

Generative models in molecular design tend to be richly parameterized, data-hungry neural models, as they must create complex structured objects as outputs. Estimating such models from data may be challenging due to the lack of sufficient…

Machine Learning · Computer Science 2021-08-17 Kevin Yang , Wengong Jin , Kyle Swanson , Regina Barzilay , Tommi Jaakkola

Diffusion models have emerged as a powerful generative method for synthesizing high-quality and diverse set of images. In this paper, we propose a video generation method based on diffusion models, where the effects of motion are modeled in…

Computer Vision and Pattern Recognition · Computer Science 2022-12-02 Kangfu Mei , Vishal M. Patel

Learning low-dimensional representations of single-cell transcriptomics has become instrumental to its downstream analysis. The state of the art is currently represented by neural network models such as variational autoencoders (VAEs) which…

Machine Learning · Computer Science 2024-02-01 Viktoria Schuster , Anders Krogh

As the amount of textual data has been rapidly increasing over the past decade, efficient similarity search methods have become a crucial component of large-scale information retrieval systems. A popular strategy is to represent original…

Information Retrieval · Computer Science 2017-08-14 Suthee Chaidaroon , Yi Fang

Deep generative models like GAN and VAE have shown impressive results in generating unconstrained objects like images. However, many design settings arising in industrial design, material science, computer graphics and more require that the…

Machine Learning · Computer Science 2024-06-07 Aaron Ferber , Arman Zharmagambetov , Taoan Huang , Bistra Dilkina , Yuandong Tian

Conditional Generative Adversarial Networks (cGAN) were designed to generate images based on the provided conditions, \eg, class-level distributions. However, existing methods have used the same generating architecture for all classes. This…

Computer Vision and Pattern Recognition · Computer Science 2021-04-07 Peng Zhou , Lingxi Xie , Xiaopeng Zhang , Bingbing Ni , Qi Tian

We present Generative Semantic Segmentation (GSS), a generative learning approach for semantic segmentation. Uniquely, we cast semantic segmentation as an image-conditioned mask generation problem. This is achieved by replacing the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-11 Jiaqi Chen , Jiachen Lu , Xiatian Zhu , Li Zhang

Generative design (GD) methods aim to automatically generate a wide variety of designs that satisfy functional or aesthetic design requirements. However, research to date generally lacks considerations of manufacturability of the generated…

Computer Vision and Pattern Recognition · Computer Science 2024-07-25 Zhichao Wang , Xiaoliang Yan , Shreyes Melkote , David Rosen

We introduce a class of auto-encoder neural networks tailored to data from the natural exponential family (e.g., count data). The architectures are inspired by the problem of learning the filters in a convolutional generative model with…

Machine Learning · Computer Science 2020-06-30 Bahareh Tolooshams , Andrew H. Song , Simona Temereanca , Demba Ba
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