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Sequence alignment is a cornerstone of bioinformatics, widely used to identify similarities between DNA, RNA, and protein sequences and studying evolutionary relationships and functional properties. The Needleman-Wunsch algorithm remains a…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-12-31 Linus Zwaka

These lecture notes are designed to accompany an imaginary, virtual, undergraduate, one or two semester course on fundamentals of Parallel Computing as well as to serve as background and reference for graduate courses on High-Performance…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-10-02 Jesper Larsson Träff

In genomics, pattern matching against a sequence of nucleotides plays a pivotal role for DNA sequence alignment and comparing genomes. This helps tackling some diseases, such as cancer in humans. The complexity of searching biological…

Quantitative Methods · Quantitative Biology 2017-10-04 Fereshte Mozafari , Hossein Babashah , Somayyeh Koohi , Zahra Kavehvash

We present a parallel algorithm and scalable implementation for genome analysis, specifically the problem of finding overlaps and alignments for data from "third generation" long read sequencers. While long sequences of DNA offer enormous…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-01-29 Marquita Ellis , Giulia Guidi , Aydın Buluç , Leonid Oliker , Katherine Yelick

Efficiently solving NP-complete problems-such as protein structure prediction, cryptographic decryption, and vulnerability detection-remains a central challenge in computer science. Traditional electronic computers, constrained by the…

Data Structures and Algorithms · Computer Science 2025-07-18 Jin Xu , XiaoLong Shi , Xin Chen , Fang Wang , Sirui Li , Pali Ye , Boliang Zhang , Di Deng , Zheng Kou , Xiaoli Qiang

This paper presents a comprehensive comparison of three dominant parallel programming models in High Performance Computing (HPC): Message Passing Interface (MPI), Open Multi-Processing (OpenMP), and Compute Unified Device Architecture…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-06-19 Nizar ALHafez , Ahmad Kurdi

Designing problems using matrices is very important in Computer Science. Fields like graph computer, graphs theory, and machine learning use matrices very often to solve their own problems. The most often matrix operation is the…

Performance · Computer Science 2019-05-10 Andre G. C. Pacheco

Nowadays, subsequence similarity search is required in a wide range of time series mining applications: climate modeling, financial forecasts, medical research, etc. In most of these applications, the Dynamic TimeWarping (DTW) similarity…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-03-09 Yana Kraeva , Mikhail Zymbler

In the area of Pattern Recognition and Matching, finding a Longest Common Subsequence plays an important role. In this paper, we have proposed one algorithm based on parallel computation. We have used OpenMP API package as middleware to…

Data Structures and Algorithms · Computer Science 2013-06-20 Tirtharaj Dash , Tanistha Nayak

DNA pattern matching is essential for many widely used bioinformatics applications. Disease diagnosis is one of these applications, since analyzing changes in DNA sequences can increase our understanding of possible genetic diseases. The…

Hardware Architecture · Computer Science 2022-06-01 Jinane Bazzi , Jana Sweidan , Mohammed E. Fouda , Rouwaida Kanj , Ahmed M. Eltawil

We propose a framework for training neural networks that are coupled with partial differential equations (PDEs) in a parallel computing environment. Unlike most distributed computing frameworks for deep neural networks, our focus is to…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-11-25 Kailai Xu , Weiqiang Zhu , Eric Darve

The difficulty of developing reliable parallel software is generating interest in deterministic environments, where a given program and input can yield only one possible result. Languages or type systems can enforce determinism in new code,…

Operating Systems · Computer Science 2010-02-01 Amittai Aviram , Bryan Ford

Regions of nested loops are a common feature of High Performance Computing (HPC) codes. In shared memory programming models, such as OpenMP, these structure are the most common source of parallelism. Parallelising these structures requires…

Programming Languages · Computer Science 2012-05-14 Adrian Jackson , Orestis Agathokleous

Parallel processing is considered as todays and future trend for improving performance of computers. Computing devices ranging from small embedded systems to big clusters of computers rely on parallelizing applications to reduce execution…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-11-27 Oussama Tahan

Optimal multiple sequence alignment by dynamic programming, like many highly dimensional scientific computing problems, has failed to benefit from the improvements in computing performance brought about by multi-processor systems, due to…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-11-30 Manal Helal , Hossam El-Gindy , Lenore Mullin , Bruno Gaeta

Future experiments in high-energy physics will pose stringent requirements to computing, in particular to real-time data processing. As an example, the CBM experiment at FAIR Germany intends to perform online data selection exclusively in…

Computational Physics · Physics 2020-02-06 V. Singhal , S. Chattopadhyay , V. Friese

We present new versions of the previously published C and CUDA programs for solving the dipolar Gross-Pitaevskii equation in one, two, and three spatial dimensions, which calculate stationary and non-stationary solutions by propagation in…

The simplex algorithm has been successfully used for many years in solving linear programming (LP) problems. Due to the intensive computations required (especially for the solution of large LP problems), parallel approaches have also…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-11-22 Basilis Mamalis , Marios Perlitis

Discovering causal relationships from data is the ultimate goal of many research areas. Constraint based causal exploration algorithms, such as PC, FCI, RFCI, PC-simple, IDA and Joint-IDA have achieved significant progress and have many…

Artificial Intelligence · Computer Science 2015-10-13 Thuc Duy Le , Tao Hoang , Jiuyong Li , Lin Liu , Shu Hu

While modern parallel computing systems provide high performance resources, utilizing them to the highest extent requires advanced programming expertise. Programming for parallel computing systems is much more difficult than programming for…

Programming Languages · Computer Science 2017-04-06 Adrian Calvo Chozas , Suejb Memeti , Sabri Pllana
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