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Efficiently acquired and precisely reconstructed imaging are crucial to the success of modern radiation therapy (RT). Computed tomography (CT) and magnetic resonance imaging (MRI) are two common modalities for providing RT treatment…

Image and Video Processing · Electrical Eng. & Systems 2025-04-15 Di Xu

As insufficient data volume and quality remain the key impediments to the adoption of modern subsymbolic AI, techniques of synthetic data generation are in high demand. Simulation offers an apt, systematic approach to generating diverse…

Artificial Intelligence · Computer Science 2026-02-18 Xiaoran Liu , Istvan David

Background Clinical trials are essential to advancing cancer treatments, yet fewer than 10% of adults with cancer enroll in trials, and many studies fail to meet accrual targets. Artificial intelligence (AI) could improve identification of…

For several cancer patients, operative resection with curative intent can end up in early recurrence of the cancer. Current limitations in peri-operative cancer staging and especially intra-operative misidentification of visible metastases…

Image and Video Processing · Electrical Eng. & Systems 2023-06-21 Thomas Schnelldorfer , Janil Castro , Atoussa Goldar-Najafi , Liping Liu

Cancer is one of the most life-threatening diseases worldwide, and head and neck (H&N) cancer is a prevalent type with hundreds of thousands of new cases recorded each year. Clinicians use medical imaging modalities such as computed…

Image and Video Processing · Electrical Eng. & Systems 2023-06-02 Ikboljon Sobirov

A brain tumor, whether benign or malignant, can potentially be life threatening and requires painstaking efforts in order to identify the type, origin and location, let alone cure one. Manual segmentation by medical specialists can be…

Image and Video Processing · Electrical Eng. & Systems 2023-05-02 Ayan Gupta , Mayank Dixit , Vipul Kumar Mishra , Attulya Singh , Atul Dayal

In oral cancer diagnostics, the limited availability of annotated datasets frequently constrains the performance of diagnostic models, particularly due to the variability and insufficiency of training data. To address these challenges, this…

Machine Learning · Computer Science 2025-08-11 Yong Oh Lee , JeeEun Kim , Jung Woo Lee

The advancement of artificial intelligence (AI) for organ segmentation and tumor detection is propelled by the growing availability of computed tomography (CT) datasets with detailed, per-voxel annotations. However, these AI models often…

Image and Video Processing · Electrical Eng. & Systems 2024-05-29 Jie Liu , Yixiao Zhang , Kang Wang , Mehmet Can Yavuz , Xiaoxi Chen , Yixuan Yuan , Haoliang Li , Yang Yang , Alan Yuille , Yucheng Tang , Zongwei Zhou

Human readers or radiologists routinely perform full-body multi-organ multi-disease detection and diagnosis in clinical practice, while most medical AI systems are built to focus on single organs with a narrow list of a few diseases. This…

The application of Deep Learning (DL) for medical diagnosis is often hampered by two problems. First, the amount of training data may be scarce, as it is limited by the number of patients who have acquired the condition to be diagnosed.…

Computer Vision and Pattern Recognition · Computer Science 2020-07-17 Diyuan Lu , Nenad Polomac , Iskra Gacheva , Elke Hattingen , Jochen Triesch

Despite the promises of data-driven artificial intelligence (AI), little is known about how we can bridge the gulf between traditional physician-driven diagnosis and a plausible future of medicine automated by AI. Specifically, how can we…

Human-Computer Interaction · Computer Science 2021-02-12 Hongyan Gu , Jingbin Huang , Lauren Hung , Xiang 'Anthony' Chen

Recently, there has been a resurgence of interest in rigorous algorithms for the inference of cancer progression from genomic data. The motivations are manifold: (i) growing NGS and single cell data from cancer patients, (ii) need for novel…

Machine Learning · Computer Science 2016-02-25 Daniele Ramazzotti

The recent development of imaging and sequencing technologies enables systematic advances in the clinical study of lung cancer. Meanwhile, the human mind is limited in effectively handling and fully utilizing the accumulation of such…

Machine Learning · Computer Science 2022-03-29 Yawei Li , Xin Wu , Ping Yang , Guoqian Jiang , Yuan Luo

Artificial Intelligence (AI) can potentially support histopathologists in the diagnosis of a broad spectrum of cancer types. In colorectal cancer (CRC), AI can alleviate the laborious task of characterization and reporting on resected…

Image and Video Processing · Electrical Eng. & Systems 2023-02-10 John-Melle Bokhorst , Iris D. Nagtegaal , Filippo Fraggetta , Simona Vatrano , Wilma Mesker , Michael Vieth , Jeroen van der Laak , Francesco Ciompi

In Canada, prostate cancer is the most common form of cancer in men and accounted for 20% of new cancer cases for this demographic in 2022. Due to recent successes in leveraging machine learning for clinical decision support, there has been…

Image and Video Processing · Electrical Eng. & Systems 2023-12-01 Aditya Sridhar , Chi-en Amy Tai , Hayden Gunraj , Yuhao Chen , Alexander Wong

Central nervous system (CNS) tumors come with the vastly heterogeneous histologic, molecular and radiographic landscape, rendering their precise characterization challenging. The rapidly growing fields of biophysical modeling and radiomics…

Quantitative Methods · Quantitative Biology 2020-06-30 Andreas Mang , Spyridon Bakas , Shashank Subramanian , Christos Davatzikos , George Biros

Synthetic generation of three-dimensional cell models from histopathological images aims to enhance understanding of cell mutation, and progression of cancer, necessary for clinical assessment and optimal treatment. Classical reconstruction…

Image and Video Processing · Electrical Eng. & Systems 2021-02-09 Yoav Alon , Xiang Yu , Huiyu Zhou

Thyroid cancer, the most prevalent endocrine cancer, has gained significant global attention due to its impact on public health. Extensive research efforts have been dedicated to leveraging artificial intelligence (AI) methods for the early…

Machine Learning · Computer Science 2024-01-09 Xinyu Zhang , Vincent CS Lee , Feng Liu

Digital pathology is not only one of the most promising fields of diagnostic medicine, but at the same time a hot topic for fundamental research. Digital pathology is not just the transfer of histopathological slides into digital…

Artificial Intelligence · Computer Science 2017-12-20 Andreas Holzinger , Bernd Malle , Peter Kieseberg , Peter M. Roth , Heimo Müller , Robert Reihs , Kurt Zatloukal

A myriad of algorithms for the automatic analysis of brain MR images is available to support clinicians in their decision-making. For brain tumor patients, the image acquisition time series typically starts with an already pathological…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Florian Kofler , Felix Meissen , Felix Steinbauer , Robert Graf , Stefan K Ehrlich , Annika Reinke , Eva Oswald , Diana Waldmannstetter , Florian Hoelzl , Izabela Horvath , Oezguen Turgut , Suprosanna Shit , Christina Bukas , Kaiyuan Yang , Johannes C. Paetzold , Ezequiel de da Rosa , Isra Mekki , Shankeeth Vinayahalingam , Hasan Kassem , Juexin Zhang , Ke Chen , Ying Weng , Alicia Durrer , Philippe C. Cattin , Julia Wolleb , M. S. Sadique , M. M. Rahman , W. Farzana , A. Temtam , K. M. Iftekharuddin , Maruf Adewole , Syed Muhammad Anwar , Ujjwal Baid , Anastasia Janas , Anahita Fathi Kazerooni , Dominic LaBella , Hongwei Bran Li , Ahmed W Moawad , Gian-Marco Conte , Keyvan Farahani , James Eddy , Micah Sheller , Sarthak Pati , Alexandros Karagyris , Alejandro Aristizabal , Timothy Bergquist , Verena Chung , Russell Takeshi Shinohara , Farouk Dako , Walter Wiggins , Zachary Reitman , Chunhao Wang , Xinyang Liu , Zhifan Jiang , Elaine Johanson , Zeke Meier , Ariana Familiar , Christos Davatzikos , John Freymann , Justin Kirby , Michel Bilello , Hassan M Fathallah-Shaykh , Roland Wiest , Jan Kirschke , Rivka R Colen , Aikaterini Kotrotsou , Pamela Lamontagne , Daniel Marcus , Mikhail Milchenko , Arash Nazeri , Marc-André Weber , Abhishek Mahajan , Suyash Mohan , John Mongan , Christopher Hess , Soonmee Cha , Javier Villanueva-Meyer , Errol Colak , Priscila Crivellaro , Andras Jakab , Abiodun Fatade , Olubukola Omidiji , Rachel Akinola Lagos , O O Olatunji , Goldey Khanna , John Kirkpatrick , Michelle Alonso-Basanta , Arif Rashid , Miriam Bornhorst , Ali Nabavizadeh , Natasha Lepore , Joshua Palmer , Antonio Porras , Jake Albrecht , Udunna Anazodo , Mariam Aboian , Evan Calabrese , Jeffrey David Rudie , Marius George Linguraru , Juan Eugenio Iglesias , Koen Van Leemput , Spyridon Bakas , Benedikt Wiestler , Ivan Ezhov , Marie Piraud , Bjoern H Menze