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In this lecture I will introduce the concept of galactic chemical evolution, namely the study of how and where the chemical elements formed and how they were distributed in the stars and gas in galaxies. The main ingredients to build models…

Astrophysics of Galaxies · Physics 2016-05-04 Francesca Matteucci

Biological systems reach organizational complexity that far exceeds the complexity of any known inanimate objects. Biological entities undoubtedly obey the laws of quantum physics and statistical mechanics. However, is modern physics…

Other Quantitative Biology · Quantitative Biology 2018-02-26 Mikhail I. Katsnelson , Yuri I. Wolf , Eugene V. Koonin

The dynamics of molecular collisions in a macroscopic body are encoded by the parameter Thermodynamic entropy - a statistical measure of the number of molecular configurations that correspond to a given macrostate. Directionality in the…

Populations and Evolution · Quantitative Biology 2020-05-22 Lloyd Demetrius , Christian Wolf

Evolution by Natural Selection is a process by which progeny inherit some properties from their progenitors with small variation. These properties are subject to Natural Selection and are called adaptive traits and carriers of the latter…

Analysis of PDEs · Mathematics 2024-01-29 Gonzalo Galiano , Yosef Cohen

Natural selection explains how life has evolved over millions of years from more primitive forms. The speed at which this happens, however, has sometimes defied formal explanations when based on random (uniformly distributed) mutations.…

Neural and Evolutionary Computing · Computer Science 2018-06-22 Santiago Hernández-Orozco , Narsis A. Kiani , Hector Zenil

Chemical evolution is essential in understanding the origins of life. We present a theory for the evolution of molecule masses and show that small molecules grow by random diffusion and large molecules by a preferential attachment process…

Populations and Evolution · Quantitative Biology 2019-12-05 Stuart A. Kauffman , David P. Jelenfi , Gabor Vattay

Evolution is the theory that plants and animals today have come from kinds that have existed in the past. Scientists such as Charles Darwin and Alfred Wallace dedicate their life to observe how species interact with their environment, grow,…

Neural and Evolutionary Computing · Computer Science 2022-09-16 Manasa Josyula

Evolution by natural selection, which is one of the most compelling themes of modern science, brought forth evolutionary algorithms and evolutionary computation, applying mechanisms of evolution in nature to various problems solved by…

Neural and Evolutionary Computing · Computer Science 2025-08-27 Eugene Eberbach

With a view to connecting random mutation on the molecular level to punctuated equilibrium behavior on the phenotype level, we propose a new model for biological evolution, which incorporates random mutation and natural selection. In this…

Condensed Matter · Physics 2009-10-28 M. Y. Choi , H. Y. Lee , D. Kim , S. H. Park

We demonstrate that the assembly pathway method underlying assembly theory (AT) is an encoding scheme widely used by popular statistical compression algorithms. We show that in all cases (synthetic or natural) AT performs similarly to other…

Information Theory · Computer Science 2024-08-15 Abicumaran Uthamacumaran , Felipe S. Abrahão , Narsis A. Kiani , Hector Zenil

Information can evolve as a physical consequence of non-equilibrium dynamics, even in the absence of genes, replication, or predefined fitness functions. We present Stability-Driven Assembly (SDA), a framework in which stochastic assembly…

Populations and Evolution · Quantitative Biology 2026-05-11 Dan Adler

Evolution of genetic code is studied as the change in the choice of enzymes that are used to synthesize amino acids from the genetic information of nucleic acids. We propose the following theory: the differentiation of physiological states…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 H. Takagi , K. Kaneko , T. Yomo

Assembly Theory (AT) and its central measure, the assembly index (Ai), represent an invaluable opportunity to address some of the most persistent and widespread conflations and misconceptions about computability and complexity theory in…

Molecular assembly offers a promising path to detect life beyond Earth, while minimizing assumptions based on terrestrial life. As mass spectrometers will be central to upcoming Solar System missions, predicting molecular assembly from…

Machine Learning · Computer Science 2025-07-28 Lindsay A. Rutter , Abhishek Sharma , Ian Seet , David Obeh Alobo , An Goto , Leroy Cronin

A central goal of evolutionary biology is to explain the origins and distribution of diversity across life. Beyond species or genetic diversity, we also observe diversity in the circuits (genetic or otherwise) underlying complex functional…

Populations and Evolution · Quantitative Biology 2018-06-06 Ali Tehrani-Saleh , Thomas LaBar , Christoph Adami

The sequence of a protein is not only constrained by its physical and biochemical properties under current selection, but also by features of its past evolutionary history. Understanding the extent and the form that these evolutionary…

Populations and Evolution · Quantitative Biology 2015-06-22 Mathieu Hemery , Olivier Rivoire

To analyze the evolutionary emergence of structural complexity in physical processes we introduce a general, but tractable, model of objects that interact to produce new objects. Since the objects--\emph{$epsilon$-machines}--have well…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 James P. Crutchfield , Olof Gornerup

This study introduces a novel theoretical framework, the Stacked Autoencoder Evolution Hypothesis, which proposes that biological evolutionary systems operate through multi-layered self-encoding and decoding processes, analogous to stacked…

Neural and Evolutionary Computing · Computer Science 2026-02-03 Hiroyuki Iizuka

We model evolution of plants in a world, made up of different locations, with multiple environments (mutually exclusive and collectively exhaustive subsets of locations). Each environment (landmass) has temperature, rainfall, and other…

Populations and Evolution · Quantitative Biology 2019-05-27 Alexander , Khazatsky , Albert Yu , Zihao Zhao , Gabe Zuckerman

Complex change is often described as "evolutionary" in economics, policy, and technology, yet most system dynamics models remain constrained to fixed state spaces and equilibrium-seeking behavior. This paper argues that evolutionary…

Populations and Evolution · Quantitative Biology 2026-02-19 Dan Adler